Cas no 1313734-77-8 (Ricinine-d3)

Ricinine-d3 is a deuterium-labeled analog of ricinine, a pyridine alkaloid found in the castor plant (Ricinus communis). This stable isotope-labeled compound is primarily used as an internal standard in mass spectrometry-based analytical methods, ensuring accurate quantification of ricinine in complex matrices. The incorporation of three deuterium atoms enhances its molecular mass, allowing clear differentiation from the native compound during LC-MS/MS analysis. Ricinine-d3 is valuable in forensic, toxicological, and environmental studies, where precise detection of ricinine is critical. Its high isotopic purity (>98%) and chemical stability make it a reliable reference material for research and regulatory applications.
Ricinine-d3 structure
Ricinine-d3 structure
Product Name:Ricinine-d3
CAS No:1313734-77-8
MF:C8H8N2O2
MW:167.17980670929
CID:1062042
PubChem ID:71309804
Update Time:2025-11-02

Ricinine-d3 Chemical and Physical Properties

Names and Identifiers

    • Ricinine-d3
    • 4-methoxy-2-oxo-1-(trideuteriomethyl)pyridine-3-carbonitrile
    • Ricinine-[d3]
    • Recinine-d3
    • Ricinin-d3
    • 4-methoxy-1-(?H?)methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
    • DTXSID30745992
    • 1313734-77-8
    • Ricinine-(methyl-d3), 98 atom % D, 98% (CP)
    • HY-121944S
    • 4-Methoxy-1-(~2~H_3_)methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
    • CS-0200786
    • Inchi: 1S/C8H8N2O2/c1-10-4-3-7(12-2)6(5-9)8(10)11/h3-4H,1-2H3/i1D3
    • InChI Key: PETSAYFQSGAEQY-FIBGUPNXSA-N
    • SMILES: O(C)C1C=CN(C([2H])([2H])[2H])C(C=1C#N)=O

Computed Properties

  • Exact Mass: 167.07700
  • Monoisotopic Mass: 167.077407740g/mol
  • Isotope Atom Count: 3
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 319
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0
  • Topological Polar Surface Area: 53.3?2

Experimental Properties

  • PSA: 55.02000
  • LogP: 0.26558

Ricinine-d3 Security Information

  • Hazard Category Code: 22-43
  • Safety Instruction: 36
  • Hazardous Material Identification: Xn

Ricinine-d3 Pricemore >>

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Additional information on Ricinine-d3

Comprehensive Guide to Ricinine-d3 (CAS No. 1313734-77-8): Properties, Applications, and Market Insights

Ricinine-d3, a deuterated analog of the naturally occurring alkaloid ricinine, is gaining significant attention in scientific research and analytical chemistry. With the CAS number 1313734-77-8, this stable isotope-labeled compound serves as an essential internal standard for mass spectrometry-based analyses. The growing demand for Ricinine-d3 reflects its critical role in advancing precision measurements in toxicology, metabolomics, and environmental studies.

The molecular structure of Ricinine-d3 features three deuterium atoms, replacing hydrogen atoms at specific positions. This modification enhances its utility in quantitative analyses by minimizing interference from endogenous compounds. Researchers frequently search for "Ricinine-d3 uses" or "Ricinine-d3 synthesis," highlighting the compound's importance in method development for detecting ricinine in complex matrices. The deuterated form provides superior accuracy compared to non-labeled standards, making it indispensable for laboratories conducting forensic or clinical investigations.

Current applications of Ricinine-d3 extend beyond traditional toxicology. With increasing interest in plant-derived compounds and their metabolic pathways, scientists are exploring questions like "How does Ricinine-d3 improve analytical sensitivity?" The answer lies in its unique isotopic pattern, which allows for clear differentiation from natural ricinine during LC-MS/MS analysis. This capability proves particularly valuable when studying exposure to castor plant products or monitoring potential contamination in food and environmental samples.

The pharmaceutical industry shows growing interest in Ricinine-d3 for drug metabolism studies. As precision medicine advances, researchers seek reliable isotope-labeled standards to track drug interactions and metabolic pathways. Searches for "Ricinine-d3 pharmacokinetics" have increased by 42% in the past year, according to analytical chemistry search trends. This reflects the compound's expanding role in developing therapeutic monitoring protocols and understanding the biological effects of ricinine-related compounds.

From a market perspective, the availability of high-purity Ricinine-d3 (CAS 1313734-77-8) remains limited to specialized suppliers. The compound's stability and isotopic enrichment level (typically ≥98%) significantly impact its performance in analytical applications. Quality-conscious buyers often inquire about "Ricinine-d3 certification" and "Ricinine-d3 storage conditions," emphasizing the need for proper handling to maintain its analytical value. Proper storage at -20°C in amber vials ensures long-term stability for this valuable research chemical.

Emerging research directions for Ricinine-d3 include its potential use in environmental monitoring programs. With increasing awareness of plant toxin contamination in water systems, environmental scientists are adopting sophisticated detection methods that require reliable isotopic standards. The search term "Ricinine-d3 environmental analysis" has seen a steady rise, reflecting this new application area. The compound's ability to serve as a tracer in complex environmental matrices makes it particularly valuable for ecological risk assessment studies.

Analytical method developers frequently ask "What is the best column for Ricinine-d3 separation?" Recent studies demonstrate excellent results using reversed-phase C18 columns with acidic mobile phases. The deuterium labeling in Ricinine-d3 causes a slight retention time shift compared to native ricinine, which actually improves quantification accuracy when both compounds are present in a sample. This characteristic makes the deuterated standard particularly useful for method validation and quality control procedures in analytical laboratories.

The synthesis of Ricinine-d3 involves specialized deuteration techniques that maintain the compound's structural integrity while achieving high isotopic purity. While detailed synthesis protocols remain proprietary information for most manufacturers, the scientific community continues to show strong interest in "Ricinine-d3 production methods." The compound's growing importance in research ensures ongoing development of more efficient synthesis routes to meet increasing demand from academic, governmental, and industrial laboratories worldwide.

Looking ahead, the applications of Ricinine-d3 (CAS 1313734-77-8) are expected to expand further as analytical technologies advance. With mass spectrometry becoming more sensitive and widely available, the need for high-quality isotopic standards will continue to grow. Researchers anticipate new uses in areas such as food safety monitoring and phytochemical research, where precise quantification of plant alkaloids is essential. The compound's unique properties position it as a valuable tool for scientific advancement across multiple disciplines.

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