Cas no 1312903-94-8 (Ethyl 5-ethoxypicolinate)

Ethyl 5-ethoxypicolinate is a versatile intermediate in organic synthesis, primarily used in pharmaceutical and agrochemical applications. Its picolinate core and ethoxy substitution enhance reactivity, making it valuable for constructing complex heterocyclic compounds. The ethyl ester group improves solubility in organic solvents, facilitating downstream reactions such as coupling or functionalization. This compound exhibits stability under standard storage conditions, ensuring consistent performance in synthetic workflows. Its structural features enable precise modifications, supporting the development of targeted bioactive molecules. Ethyl 5-ethoxypicolinate is particularly useful in medicinal chemistry for scaffold diversification and lead optimization. High purity grades are available to meet rigorous research and industrial requirements.
Ethyl 5-ethoxypicolinate structure
Ethyl 5-ethoxypicolinate structure
Product Name:Ethyl 5-ethoxypicolinate
CAS No:1312903-94-8
MF:C10H13NO3
MW:195.215122938156
MDL:MFCD23135680
CID:1038717
PubChem ID:67958698
Update Time:2025-05-25

Ethyl 5-ethoxypicolinate Chemical and Physical Properties

Names and Identifiers

    • Ethyl 5-ethoxypicolinate
    • Ethyl 5-ethoxypicolite
    • ethyl 5-ethoxypyridine-2-carboxylate
    • 2-Pyridinecarboxylic acid, 5-ethoxy-, ethyl ester
    • GURVKDSNNLEJBB-UHFFFAOYSA-N
    • 1312903-94-8
    • SCHEMBL9901416
    • Ethyl5-ethoxypicolinate
    • DTXSID40737848
    • MDL: MFCD23135680
    • Inchi: 1S/C10H13NO3/c1-3-13-8-5-6-9(11-7-8)10(12)14-4-2/h5-7H,3-4H2,1-2H3
    • InChI Key: GURVKDSNNLEJBB-UHFFFAOYSA-N
    • SMILES: O(CC)C1=CN=C(C(=O)OCC)C=C1

Computed Properties

  • Exact Mass: 195.09000
  • Monoisotopic Mass: 195.08954328g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 5
  • Complexity: 184
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.7
  • Topological Polar Surface Area: 48.4?2

Experimental Properties

  • PSA: 48.42000
  • LogP: 1.65700

Ethyl 5-ethoxypicolinate Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Ethyl 5-ethoxypicolinate Pricemore >>

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Ethyl 5-ethoxypicolinate Production Method

Additional information on Ethyl 5-ethoxypicolinate

Ethyl 5-Ethoxypicolinate: A Comprehensive Overview

Ethyl 5-ethoxypicolinate, with the CAS number 1312903-94-8, is a compound that has garnered significant attention in recent years due to its unique properties and potential applications. This compound belongs to the class of organic chemicals known as esters, specifically derived from picolinic acid. Its structure consists of a picolinate moiety with an ethoxy group at the 5-position, making it a derivative of picolinic acid. The compound's name, Ethyl 5-ethoxypicolinate, reflects its ethyl ester functional group and the substitution pattern on the picoline ring.

Recent studies have highlighted the importance of Ethyl 5-ethoxypicolinate in various fields, particularly in agriculture and plant science. The compound has been investigated for its role as a plant growth regulator and its potential to enhance crop yields. Researchers have found that Ethyl 5-ethoxypicolinate can influence plant metabolism by modulating key enzymes involved in photosynthesis and stress response pathways. This makes it a promising candidate for developing eco-friendly agricultural solutions.

The synthesis of Ethyl 5-ethoxypicolinate involves a multi-step process that typically begins with the preparation of picolinic acid derivatives. One common method involves the esterification of picolinic acid with ethanol in the presence of an appropriate catalyst. The substitution at the 5-position with an ethoxy group is achieved through nucleophilic aromatic substitution or other advanced organic synthesis techniques. The CAS number 1312903-94-8 is associated with this specific compound, ensuring its identity and purity in scientific literature and commercial applications.

One of the most exciting developments involving Ethyl 5-ethoxypicolinate is its application in enhancing abiotic stress tolerance in plants. Studies have shown that when applied as a foliar spray, this compound can significantly improve plant resilience to environmental stresses such as drought, high salinity, and extreme temperatures. This effect is attributed to its ability to modulate reactive oxygen species (ROS) levels and activate antioxidant defense mechanisms in plants.

In addition to its agricultural applications, Ethyl 5-ethoxypicolinate has also been explored for its potential in biotechnology and pharmaceutical research. Its structural similarity to certain bioactive compounds suggests that it could serve as a lead molecule for drug discovery. Researchers are currently investigating its role in modulating cellular signaling pathways and its potential as an anti-inflammatory or antioxidant agent.

The environmental impact of Ethyl 5-ethoxypicolinate has also been a topic of interest. Studies indicate that it degrades relatively quickly under aerobic conditions, reducing its persistence in soil and water systems. This makes it a more sustainable option compared to some traditional agrochemicals. However, further research is needed to fully understand its long-term ecological effects and ensure safe application practices.

In conclusion, Ethyl 5-ethoxypicolinate (CAS number 1312903-94-8) is a versatile compound with a wide range of potential applications. From enhancing crop resilience to serving as a lead molecule in drug discovery, this compound continues to be a focal point for researchers across various disciplines. As new studies emerge, we can expect even more innovative uses for this intriguing chemical entity.

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