• 1. High desolvation temperature facilitates the ESI-source H/D exchange at non-labile sites of hydroxybenzoic acids and aromatic amino acids
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• 2. Polyketo-enols and chelates. Part II. The chemistry of the xanthophanic enols
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• 3. Spectrophotometric determination of trace amounts of iron(III) in salicylates by extraction of the mixed-ligand iron-salicylate-purpurin complex
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• 4. Spectrophotometric determination of trace amounts of iron(III) in salicylates by extraction of the mixed-ligand iron-salicylate-purpurin complex
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• 5. Simultaneous determination of acetylsalicylic and salicylic acids in human serum and aspirin formulations by second-derivative synchronous fluorescence spectrometry
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

Comprehensive Overview of 5-Acetylsalicylic Acid (CAS No. 13110-96-8): Properties, Applications, and Modern Research Insights

5-Acetylsalicylic acid (CAS No. 13110-96-8), a derivative of salicylic acid, has garnered significant attention in pharmaceutical and biochemical research due to its unique structural properties and potential therapeutic applications. Often compared to its well-known relative, acetylsalicylic acid (aspirin), this compound exhibits distinct characteristics that make it a subject of ongoing scientific exploration. In this article, we delve into its molecular structure, synthesis methods, and emerging roles in health science, addressing common queries such as "5-acetylsalicylic acid vs aspirin" and "benefits of 5-acetylsalicylic acid in skincare."

The chemical formula of 5-acetylsalicylic acid (C₉H₈O₄) features an acetyl group bonded to the hydroxyl position of salicylic acid, altering its reactivity and bioavailability. Researchers highlight its stability under physiological conditions, a trait frequently searched in terms like "5-acetylsalicylic acid solubility" and "pH stability of CAS 13110-96-8." These properties are critical for formulating controlled-release medications and topical preparations, where gradual hydrolysis is desirable.

Recent studies have explored 5-acetylsalicylic acid's anti-inflammatory mechanisms, particularly its cyclooxygenase (COX) inhibition profile. Unlike traditional NSAIDs, its metabolite pathways may reduce gastrointestinal irritation—a hot topic in forums discussing "gentler alternatives to aspirin." Additionally, its potential antioxidant effects have sparked interest in anti-aging research, with keywords like "5-acetylsalicylic acid for collagen synthesis" gaining traction in dermatology circles.

In industrial applications, CAS 13110-96-8 serves as an intermediate in synthesizing specialized polymers and coatings. Its bifunctional structure allows cross-linking in biodegradable materials, aligning with sustainability trends reflected in searches for "eco-friendly pharmaceutical excipients." Analytical techniques such as HPLC and NMR (frequently asked about in "how to identify 5-acetylsalicylic acid purity") confirm its suitability for high-precision formulations.

Safety profiles of 5-acetylsalicylic acid remain a priority, with regulatory databases emphasizing proper handling protocols. While not classified as hazardous, queries like "is 5-acetylsalicylic acid safe for long-term use" underscore the need for continued pharmacological studies. Current data suggest lower platelet aggregation effects compared to aspirin, making it a candidate for cardiovascular research—addressing searches on "novel antithrombotic agents."

Future directions include nanotechnology integrations, where 5-acetylsalicylic acid's molecular size enables drug-loading in liposomal carriers (a trending topic in "targeted drug delivery systems 2024"). As synthetic biology advances, engineered biosynthesis routes may optimize production efficiency, responding to industry demands highlighted by "green chemistry in API manufacturing."

This overview underscores the multifaceted nature of 5-acetylsalicylic acid (CAS No. 13110-96-8), bridging foundational chemistry with cutting-edge applications. By addressing both academic and public interest areas—from "mechanism of action" to "cosmeceutical potentials"—we aim to provide a resource that satisfies diverse informational needs while adhering to SEO best practices through semantically rich keyword integration.

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