Cas no 13095-48-2 (Pentanedioic acid,2-hydroxy-, (2S)-)

Pentanedioic acid,2-hydroxy-, (2S)- structure
13095-48-2 structure
Product Name:Pentanedioic acid,2-hydroxy-, (2S)-
CAS No:13095-48-2
MF:C5H8O5
MW:148.114022254944
CID:227333
PubChem ID:439939
Update Time:2025-07-15

Pentanedioic acid,2-hydroxy-, (2S)- Chemical and Physical Properties

Names and Identifiers

    • Pentanedioic acid,2-hydroxy-, (2S)-
    • (2S)-2-Hydroxyglutaric Acid
    • (2S)-2-hydroxypentanedioic acid
    • (2S)-hydroxyglutaric acid
    • (S)-2-hydroxy-glutaric acid
    • (S)-2-Hydroxy-glutarsaeure
    • [3H]-L-2-Hydroxyglutarate
    • L-2-Hydroxyglutaric acid
    • L-2-hydroxyglutaric disodium salt
    • L-hydroxyglutaric acid
    • (S)-alpha-Hydroxyglutaric acid
    • L-2-Hydroxyglutarate
    • L-alpha-Hydroxyglutaric acid
    • L--Hydroxyglutaric Acid
    • (S)-2-Hydroxyglutaric acid
    • BDBM50344962
    • L-a-Hydroxyglutarate
    • SCHEMBL864236
    • Q27104223
    • (S)-2-Hydroxypentanedioic Acid
    • L-.ALPHA.-HYDROXYGLUTARIC ACID
    • DTXSID901020882
    • CHEMBL1615211
    • 2-hydroxy-(S)-Pentanedioate
    • UNII-7Z2F3DYB8K
    • (S)-.ALPHA.-HYDROXYGLUTARIC ACID
    • 2-hydroxy-L-Glutarate
    • (S)-a-Hydroxyglutaric acid
    • (S)-alpha-Hydroxyglutarate
    • AKOS006378214
    • L-a-Hydroxyglutaric acid
    • 2-hydroxy-(S)-Pentanedioic acid
    • 2-hydroxy-L-Glutaric acid
    • CHEBI:32797
    • (S)-a-Hydroxyglutarate
    • L-alpha-Hydroxyglutarate
    • 13095-48-2
    • (S)-2-Hydroxyglutarate
    • HY-113039
    • NS00122108
    • J-005908
    • C03196
    • 2-Hydroxyglutaric acid, (S)-
    • CS-0059412
    • S2G
    • 7Z2F3DYB8K
    • Pentanedioic acid, 2-hydroxy-, (2S)-
    • A900995
    • Inchi: 1S/C5H8O5/c6-3(5(9)10)1-2-4(7)8/h3,6H,1-2H2,(H,7,8)(H,9,10)/t3-/m0/s1
    • InChI Key: HWXBTNAVRSUOJR-VKHMYHEASA-N
    • SMILES: O[C@H](C(=O)O)CCC(=O)O

Computed Properties

  • Exact Mass: 148.03700
  • Monoisotopic Mass: 148.03717335g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 4
  • Complexity: 141
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -1
  • Topological Polar Surface Area: 94.8?2

Experimental Properties

  • Density: 1.508±0.06 g/cm3 (20 oC 760 Torr),
  • Solubility: Soluble (840 g/l) (25 o C),
  • PSA: 94.83000
  • LogP: -0.70330

Pentanedioic acid,2-hydroxy-, (2S)- Security Information

  • Storage Condition:Please store the product under the recommended conditions in the Certificate of Analysis.

Pentanedioic acid,2-hydroxy-, (2S)- Customs Data

  • HS CODE:2918199090
  • Customs Data:

    China Customs Code:

    2918199090

    Overview:

    HS: 2918199090. Other alcohol containing but not other oxy carboxylic acids(Including its anhydride\Acyl halide\Peroxides, peroxyacids and derivatives of this tax number). VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:6.5%.General tariff:30.0%

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Pentanedioic acid,2-hydroxy-, (2S)- Suppliers

Amadis Chemical Company Limited
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(CAS:13095-48-2)Pentanedioic acid,2-hydroxy-, (2S)-
Order Number:A900995
Stock Status:in Stock
Quantity:250mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 12:07
Price ($):1084.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
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(CAS:13095-48-2)S-2-羥基戊二酸
Order Number:LE26563331
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:56
Price ($):discuss personally

Additional information on Pentanedioic acid,2-hydroxy-, (2S)-

Pentanedioic acid,2-hydroxy-, (2S)- (CAS No: 13095-48-2): A Comprehensive Overview in Modern Chemical Biology

Pentanedioic acid,2-hydroxy-, (2S)-, identified by its CAS number 13095-48-2, is a compound of significant interest in the field of chemical biology and pharmaceutical research. This enantiomerically pure compound, characterized by its (2S) configuration, has garnered attention due to its unique structural and functional properties. As a derivative of pentanedioic acid, it exhibits distinct chemical reactivity and biological interactions that make it a valuable tool in the development of novel therapeutic agents.

The molecular structure of Pentanedioic acid,2-hydroxy-, (2S)- consists of a five-carbon chain with carboxyl groups at both ends and a hydroxyl group at the second carbon position. This specific arrangement imparts a high degree of stereochemical complexity, which is crucial for its role in biological systems. The (2S) configuration indicates the spatial orientation of the hydroxyl group, influencing its interactions with enzymes and other biomolecules.

In recent years, the study of chiral compounds like Pentanedioic acid,2-hydroxy-, (2S)- has been at the forefront of research in drug discovery. The concept that enantiomers can have vastly different biological activities has been well-documented. For instance, one enantiomer may exhibit potent therapeutic effects while another may be inactive or even harmful. This duality underscores the importance of stereochemical purity in pharmaceutical development.

Current research highlights the potential applications of Pentanedioic acid,2-hydroxy-, (2S)- in modulating metabolic pathways and enzyme activities. Studies have shown that this compound can interact with various enzymes involved in glycolysis and the citric acid cycle, suggesting its utility in treating metabolic disorders. Additionally, its ability to act as a substrate or inhibitor for specific enzymes makes it a promising candidate for developing targeted therapies.

The synthesis of Pentanedioic acid,2-hydroxy-, (2S)- is a challenging yet fascinating aspect of organic chemistry. Advanced synthetic methodologies, including asymmetric synthesis and chiral resolution techniques, are employed to achieve high enantiomeric purity. These methods not only require meticulous planning but also offer insights into the fundamental principles of molecular stereochemistry.

One notable application of Pentanedioic acid,2-hydroxy-, (2S)- is in the field of enzyme inhibition research. By binding to specific active sites on enzymes, this compound can alter metabolic pathways or regulate cellular processes. Such interactions are being explored for their potential in treating conditions like diabetes, obesity, and cardiovascular diseases. The precise stereochemistry of Pentanedioic acid,2-hydroxy-, (2S)- ensures that it can selectively target particular enzymes without affecting others.

Recent advancements in computational chemistry have further enhanced our understanding of how Pentanedioic acid,2-hydroxy-, (2S)- interacts with biological targets. Molecular modeling techniques allow researchers to predict binding affinities and identify potential drug candidates with high accuracy. These simulations have been instrumental in optimizing synthetic routes and designing derivatives with improved pharmacological properties.

The role of Pentanedioic acid,2-hydroxy-, (2S)- in drug development extends beyond enzyme inhibition. It has also been investigated for its potential as an antioxidant and anti-inflammatory agent. The hydroxyl group in its structure contributes to its ability to scavenge free radicals and modulate inflammatory responses. Such properties make it a versatile compound with broad therapeutic implications.

In conclusion, Pentanedioic acid,2-hydroxy-, (2S)- represents a significant advancement in chemical biology and pharmaceutical research. Its unique structural features and biological interactions make it a valuable tool for developing novel therapeutic agents. As research continues to uncover new applications for this compound, its importance in addressing various health challenges is likely to grow.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:13095-48-2)Pentanedioic acid,2-hydroxy-, (2S)-
A900995
Purity:99%
Quantity:250mg
Price ($):1084.0
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:13095-48-2)S-2-羥基戊二酸
LE26563331
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
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