Cas no 130608-03-6 (1-Phenylbut-3-en-1-amine)

1-Phenylbut-3-en-1-amine is a chiral amine compound featuring a phenyl group and a terminal alkene functionality. Its structure makes it a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. The presence of both an amine and an alkene group allows for diverse reactivity, including nucleophilic additions, Michael additions, and transition-metal-catalyzed cross-coupling reactions. The compound’s stereogenic center also enables its use in asymmetric synthesis, where enantioselective transformations are critical. Its stability under standard conditions and compatibility with a range of reaction conditions enhance its utility in multi-step synthetic routes.
1-Phenylbut-3-en-1-amine structure
1-Phenylbut-3-en-1-amine structure
Product Name:1-Phenylbut-3-en-1-amine
CAS No:130608-03-6
MF:C10H13N
MW:147.216922521591
CID:4693349
Update Time:2025-05-22

1-Phenylbut-3-en-1-amine Chemical and Physical Properties

Names and Identifiers

    • 1-phenylbut-3-en-1-amine
    • (R)-4-amino-4-phenyl-1-butene
    • 1-phenyl-but-3-enyl-amine
    • Benzenemethanamine, a-2-propenyl-
    • (S)-1-PHENYLBUT-3-EN-1-AMINE
    • 1-Phenylbut-3-en-1-amine
    • Inchi: 1S/C10H13N/c1-2-6-10(11)9-7-4-3-5-8-9/h2-5,7-8,10H,1,6,11H2
    • InChI Key: FAOYSBDLLGZOKF-UHFFFAOYSA-N
    • SMILES: NC(CC=C)C1C=CC=CC=1

Computed Properties

  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 3
  • Complexity: 114
  • Topological Polar Surface Area: 26

1-Phenylbut-3-en-1-amine Pricemore >>

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Additional information on 1-Phenylbut-3-en-1-amine

Comprehensive Overview of 1-Phenylbut-3-en-1-amine (CAS No. 130608-03-6): Properties, Applications, and Industry Insights

1-Phenylbut-3-en-1-amine (CAS No. 130608-03-6) is an organic compound featuring a phenyl group attached to a butenylamine backbone. This structure grants it unique reactivity, making it valuable in synthetic chemistry, pharmaceuticals, and material science. Researchers and manufacturers increasingly focus on this compound due to its versatility in constructing complex molecules, particularly in asymmetric synthesis and catalytic transformations.

The growing interest in amine derivatives like 1-Phenylbut-3-en-1-amine aligns with trends in green chemistry and sustainable synthesis. Users frequently search for "how to synthesize 1-Phenylbut-3-en-1-amine" or "applications of unsaturated amines," reflecting demand for eco-friendly methodologies. Recent studies highlight its role in click chemistry and bioorthogonal reactions, which are pivotal in drug discovery and bioconjugation.

From a structural perspective, the vinyl group in 1-Phenylbut-3-en-1-amine enables functionalization via hydroamination or polymerization, answering queries like "can 1-Phenylbut-3-en-1-amine form polymers?" Its chiral center also makes it a candidate for enantioselective catalysis, addressing searches for "chiral amine catalysts." Analytical techniques such as NMR and HPLC are commonly employed to characterize its purity, a topic often queried in academic forums.

In pharmaceuticals, 1-Phenylbut-3-en-1-amine serves as an intermediate for active pharmaceutical ingredients (APIs). Its derivatization potential links to trending topics like "small-molecule drug development" and "targeted therapy scaffolds." Notably, its compatibility with microwave-assisted synthesis—a popular search term—enhances its appeal for high-throughput screening.

Industrial applications include adhesives and specialty coatings, where its amine functionality improves cross-linking efficiency. Searches for "amine-based adhesives" or "high-performance coatings" underscore this relevance. Regulatory compliance (e.g., REACH) and safety data (SDS for 1-Phenylbut-3-en-1-amine) are additional high-traffic topics, emphasizing the need for transparent documentation.

Future research may explore 1-Phenylbut-3-en-1-amine in photoredox catalysis or AI-driven molecular design, aligning with breakthroughs in computational chemistry. As industries prioritize carbon-neutral synthesis, this compound’s role in atom-economical reactions will likely expand, addressing global searches for "sustainable chemical processes."

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