Cas no 1289217-19-1 (2-Chloro-4-propoxypyridine)

2-Chloro-4-propoxypyridine is a halogenated pyridine derivative characterized by the presence of a chloro substituent at the 2-position and a propoxy group at the 4-position of the pyridine ring. This compound serves as a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and specialty chemicals. Its reactive chloro group enables further functionalization through nucleophilic substitution, while the propoxy moiety enhances solubility and influences electronic properties. The compound's stable pyridine core ensures compatibility with a range of reaction conditions. It is commonly utilized in cross-coupling reactions and as a building block for heterocyclic systems, offering synthetic flexibility for targeted molecular design.
2-Chloro-4-propoxypyridine structure
2-Chloro-4-propoxypyridine structure
Product Name:2-Chloro-4-propoxypyridine
CAS No:1289217-19-1
MF:C8H10ClNO
MW:171.624101161957
MDL:MFCD18885848
CID:2112778
Update Time:2025-05-22

2-Chloro-4-propoxypyridine Chemical and Physical Properties

Names and Identifiers

    • 2-chloro-4-propoxyPyridine
    • Pyridine, 2-chloro-4-propoxy-
    • 2-Chloro-4-propoxypyridine
    • MDL: MFCD18885848
    • Inchi: 1S/C8H10ClNO/c1-2-5-11-7-3-4-10-8(9)6-7/h3-4,6H,2,5H2,1H3
    • InChI Key: OIGJQVUVYVQNBR-UHFFFAOYSA-N
    • SMILES: ClC1C=C(C=CN=1)OCCC

Computed Properties

  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 3
  • Complexity: 110
  • Topological Polar Surface Area: 22.1

2-Chloro-4-propoxypyridine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Matrix Scientific
190590-2.500g
2-Chloro-4-propoxypyridine, 95%
1289217-19-1 95%
2.500g
$1320.00 2023-09-07
A2B Chem LLC
AJ38827-2.5g
2-chloro-4-propoxypyridine
1289217-19-1 95%
2.5g
$888.00 2024-04-20

Additional information on 2-Chloro-4-propoxypyridine

Comprehensive Overview of 2-Chloro-4-propoxypyridine (CAS No. 1289217-19-1): Properties, Applications, and Industry Insights

2-Chloro-4-propoxypyridine (CAS No. 1289217-19-1) is a specialized organic compound gaining traction in pharmaceutical and agrochemical research due to its unique structural properties. As a halogenated pyridine derivative, it serves as a versatile intermediate in synthesizing bioactive molecules. The compound's propoxy and chloro functional groups enhance its reactivity, making it valuable for cross-coupling reactions and heterocyclic modifications—a topic frequently searched in AI-driven drug discovery forums.

Recent trends highlight growing interest in sustainable synthesis methods for pyridine derivatives, aligning with the demand for green chemistry solutions. Researchers often query "eco-friendly synthesis of 2-Chloro-4-propoxypyridine" or "alternatives to traditional halogenation," reflecting industry shifts toward reduced environmental impact. This compound's stability under mild conditions also makes it a candidate for flow chemistry applications—a hot topic in process optimization discussions.

In pharmaceutical contexts, 1289217-19-1 is explored for its potential as a kinase inhibitor scaffold, with patent databases showing increased activity around related structures. SEO analytics reveal high search volumes for "pyridine-based drug intermediates" and "CAS 1289217-19-1 suppliers," underscoring commercial relevance. Analytical challenges, such as HPLC purity testing for this compound, are another frequent search theme among quality control professionals.

The agrochemical sector leverages 2-Chloro-4-propoxypyridine in developing novel crop protection agents, particularly for fungicide formulations. With rising global focus on food security, searches for "new mode-of-action pesticides" often intersect with this chemistry. Regulatory databases indicate growing submissions for analogs, suggesting expanding applications.

From a technical perspective, the compound's logP value and hydrogen bonding capacity are critical parameters for researchers optimizing ADME properties—a recurring topic in medicinal chemistry webinars. Spectral data (NMR, MS) for CAS 1289217-19-1 ranks among top-downloaded datasets in compound libraries, reflecting its utility in structure verification workflows.

Supply chain dynamics for this niche chemical show regional variations, with "2-Chloro-4-propoxypyridine manufacturer certification" being a key procurement consideration. Analytical method development papers citing this compound frequently appear in journals covering advanced separation techniques, correlating with instrumentation vendor search trends.

Emerging applications in material science, particularly as a ligand for catalysts in OLED manufacturing, have sparked academic interest. Patent landscaping reveals innovative uses in electronic materials, aligning with searches for "pyridine derivatives in optoelectronics." This multidisciplinary relevance positions 1289217-19-1 as a compound bridging pharmaceutical and technological innovation.

Storage and handling protocols for 2-Chloro-4-propoxypyridine often generate technical queries, especially regarding long-term stability under nitrogen. Industry forums show active discussions on scaling up pyridine derivatives, with case studies referencing this specific compound's crystallization behavior—a pain point in process chemistry.

As regulatory landscapes evolve, particularly in REACH compliance for specialty chemicals, CAS 1289217-19-1 appears in several pre-registration dossiers. This regulatory attention coincides with search spikes for "pyridine derivative safety profiles" among EHS professionals. The compound's structure-activity relationship studies also feature prominently in computational chemistry publications.

Market intelligence indicates steady growth in demand for halogenated pyridines, with 2-Chloro-4-propoxypyridine representing a strategic intermediate. Procurement teams frequently search for "custom synthesis of CAS 1289217-19-1," highlighting needs for tailored quantities and specifications. This aligns with broader industry movements toward just-in-time chemical sourcing models.

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