Cas no 1286273-41-3 (3-(Piperidin-1-yl)pyridin-2-amine)
3-(Piperidin-1-yl)pyridin-2-amine is a heterocyclic compound featuring a pyridine core substituted with a piperidine moiety at the 3-position and an amino group at the 2-position. This structure imparts unique physicochemical properties, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. Its piperidine ring enhances lipophilicity and bioavailability, while the pyridine-amine scaffold offers versatile reactivity for further functionalization. The compound exhibits potential as a building block for bioactive molecules, particularly in the development of kinase inhibitors and CNS-targeting agents. Its balanced polarity and stability under various conditions facilitate its use in medicinal chemistry optimization. The presence of both basic nitrogen atoms allows for salt formation, improving solubility for formulation purposes.
1286273-41-3 structure
Product Name:3-(Piperidin-1-yl)pyridin-2-amine
CAS No:1286273-41-3
MF:C10H15N3
MW:177.246201753616
CID:4586233
PubChem ID:69299607
Update Time:2025-07-02
3-(Piperidin-1-yl)pyridin-2-amine Chemical and Physical Properties
Names and Identifiers
-
- 3-(Piperidin-1-yl)pyridin-2-amine
- 3-piperidin-1-ylpyridin-2-amine
- SB42312
-
- Inchi: 1S/C10H15N3/c11-10-9(5-4-6-12-10)13-7-2-1-3-8-13/h4-6H,1-3,7-8H2,(H2,11,12)
- InChI Key: XOGBXNJMGNHPDP-UHFFFAOYSA-N
- SMILES: N1(C2=CC=CN=C2N)CCCCC1
Computed Properties
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 13
- Rotatable Bond Count: 1
- Complexity: 154
- XLogP3: 1.5
- Topological Polar Surface Area: 42.2
Experimental Properties
- Density: 1.1±0.1 g/cm3
- Boiling Point: 329.0±27.0 °C at 760 mmHg
- Flash Point: 152.8±23.7 °C
- Vapor Pressure: 0.0±0.7 mmHg at 25°C
3-(Piperidin-1-yl)pyridin-2-amine Security Information
- Signal Word:warning
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement: P264+P280+P305+P351+P338+P337+P313
- Safety Instruction: H303+H313+H333
- Storage Condition:storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
3-(Piperidin-1-yl)pyridin-2-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | B449578-10mg |
3-(piperidin-1-yl)pyridin-2-amine |
1286273-41-3 | 10mg |
$ 50.00 | 2022-06-07 | ||
| TRC | B449578-50mg |
3-(piperidin-1-yl)pyridin-2-amine |
1286273-41-3 | 50mg |
$ 210.00 | 2022-06-07 | ||
| TRC | B449578-100mg |
3-(piperidin-1-yl)pyridin-2-amine |
1286273-41-3 | 100mg |
$ 320.00 | 2022-06-07 | ||
| Apollo Scientific | OR52769-100mg |
3-(1-Piperidyl)pyridin-2-amine |
1286273-41-3 | 95% | 100mg |
£320.00 | 2025-02-20 | |
| Apollo Scientific | OR52769-250mg |
3-(1-Piperidyl)pyridin-2-amine |
1286273-41-3 | 95% | 250mg |
£420.00 | 2025-02-20 | |
| Enamine | EN300-134978-0.05g |
3-(piperidin-1-yl)pyridin-2-amine |
1286273-41-3 | 95% | 0.05g |
$200.0 | 2023-06-06 | |
| Enamine | EN300-134978-0.1g |
3-(piperidin-1-yl)pyridin-2-amine |
1286273-41-3 | 95% | 0.1g |
$298.0 | 2023-06-06 | |
| Enamine | EN300-134978-0.25g |
3-(piperidin-1-yl)pyridin-2-amine |
1286273-41-3 | 95% | 0.25g |
$425.0 | 2023-06-06 | |
| Enamine | EN300-134978-0.5g |
3-(piperidin-1-yl)pyridin-2-amine |
1286273-41-3 | 95% | 0.5g |
$668.0 | 2023-06-06 | |
| Enamine | EN300-134978-1.0g |
3-(piperidin-1-yl)pyridin-2-amine |
1286273-41-3 | 95% | 1g |
$857.0 | 2023-06-06 |
3-(Piperidin-1-yl)pyridin-2-amine Related Literature
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Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
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Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
-
Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
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