Cas no 1274903-40-0 ((3-trifluoromethanesulfonylphenyl)methanamine)
(3-Trifluoromethanesulfonylphenyl)methanamine is a versatile aromatic amine compound featuring a trifluoromethanesulfonyl (triflyl) group at the meta position relative to the aminomethyl substituent. The electron-withdrawing triflyl group enhances the compound's reactivity in nucleophilic substitution and metal-catalyzed coupling reactions, making it valuable for pharmaceutical and agrochemical synthesis. The presence of both amine and sulfonyl functionalities allows for diverse derivatization, enabling applications as a building block in medicinal chemistry, particularly for designing bioactive molecules with improved metabolic stability. Its structural features contribute to enhanced lipophilicity and membrane permeability, beneficial for drug discovery. The compound's stability under various reaction conditions and compatibility with common protecting groups further increases its utility in multi-step synthetic routes.
1274903-40-0 structure
Product Name:(3-trifluoromethanesulfonylphenyl)methanamine
CAS No:1274903-40-0
MF:C8H8F3NO2S
MW:239.214831352234
MDL:MFCD25460327
CID:4692672
PubChem ID:69971943
Update Time:2025-07-02
(3-trifluoromethanesulfonylphenyl)methanamine Chemical and Physical Properties
Names and Identifiers
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- 3-(Trifluoromethylsulfonyl)benzylamine
- (3-trifluoromethanesulfonylphenyl)methanamine
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- MDL: MFCD25460327
- Inchi: 1S/C8H8F3NO2S/c9-8(10,11)15(13,14)7-3-1-2-6(4-7)5-12/h1-4H,5,12H2
- InChI Key: YQPOVRLFYHVUFY-UHFFFAOYSA-N
- SMILES: S(C(F)(F)F)(C1C=CC=C(CN)C=1)(=O)=O
Computed Properties
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 15
- Rotatable Bond Count: 2
- Complexity: 307
- XLogP3: 0.7
- Topological Polar Surface Area: 68.5
(3-trifluoromethanesulfonylphenyl)methanamine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| abcr | AB254846-1 g |
3-(Trifluoromethylsulfonyl)benzylamine, 98%; . |
1274903-40-0 | 98% | 1 g |
€699.00 | 2023-07-20 | |
| eNovation Chemicals LLC | D779766-1g |
3-[(Trifluoromethyl)sulfonyl]benzylamine |
1274903-40-0 | 95% | 1g |
$935 | 2025-02-26 | |
| eNovation Chemicals LLC | D779766-1g |
3-[(Trifluoromethyl)sulfonyl]benzylamine |
1274903-40-0 | 95% | 1g |
$935 | 2025-02-24 | |
| eNovation Chemicals LLC | D779766-1g |
3-[(Trifluoromethyl)sulfonyl]benzylamine |
1274903-40-0 | 95% | 1g |
$935 | 2024-07-20 | |
| abcr | AB254846-1g |
3-(Trifluoromethylsulfonyl)benzylamine, 98%; . |
1274903-40-0 | 98% | 1g |
€699.00 | 2025-04-21 | |
| Enamine | EN300-248043-1g |
(3-trifluoromethanesulfonylphenyl)methanamine |
1274903-40-0 | 1g |
$937.0 | 2023-09-15 | ||
| Enamine | EN300-248043-5g |
(3-trifluoromethanesulfonylphenyl)methanamine |
1274903-40-0 | 5g |
$3855.0 | 2023-09-15 | ||
| Enamine | EN300-248043-10g |
(3-trifluoromethanesulfonylphenyl)methanamine |
1274903-40-0 | 10g |
$7513.0 | 2023-09-15 | ||
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1356773-1g |
(3-((Trifluoromethyl)sulfonyl)phenyl)methanamine |
1274903-40-0 | 98% | 1g |
¥8568.00 | 2024-08-09 | |
| Enamine | EN300-248043-0.05g |
(3-trifluoromethanesulfonylphenyl)methanamine |
1274903-40-0 | 95% | 0.05g |
$786.0 | 2024-06-19 |
(3-trifluoromethanesulfonylphenyl)methanamine Related Literature
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1. An all-solid-state imprinted polymer-based potentiometric sensor for determination of bisphenol S?Rongning Liang,Tanji Yin,Ruiqing Yao,Wei Qin RSC Adv., 2016,6, 73308-73312
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Ravi Kumar Yadav,R. Govindaraj Phys. Chem. Chem. Phys., 2020,22, 26876-26886
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Alvin Tanudjaja,Shinsuke Inagi,Fusao Kitamura,Toshikazu Takata,Ikuyoshi Tomita Dalton Trans., 2021,50, 3037-3043
-
Karl Crowley,Eimer O'Malley,Aoife Morrin,Malcolm R. Smyth,Anthony J. Killard Analyst, 2008,133, 391-399
-
Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
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