Cas no 1268521-10-3 (rac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo4.1.0heptane-3-carboxylate, cis)

Technical Introduction: rac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate (cis) is a bicyclic heterocyclic compound featuring a fused oxirane and aziridine ring system. Its cis configuration ensures stereochemical consistency, making it valuable for applications requiring precise spatial orientation. The tert-butyloxycarbonyl (Boc) protecting group enhances stability, facilitating handling and storage while allowing selective deprotection under mild acidic conditions. This compound serves as a versatile intermediate in organic synthesis, particularly for the construction of complex pharmacophores or chiral scaffolds. Its rigid bicyclic structure and functional group compatibility make it suitable for exploring structure-activity relationships in medicinal chemistry. High purity and well-defined stereochemistry ensure reproducibility in research and industrial settings.
rac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo4.1.0heptane-3-carboxylate, cis structure
1268521-10-3 structure
Product Name:rac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo4.1.0heptane-3-carboxylate, cis
CAS No:1268521-10-3
MF:C10H17NO3
MW:199.246883153915
MDL:MFCD14582439
CID:4787058
PubChem ID:23583162
Update Time:2026-02-27

rac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo4.1.0heptane-3-carboxylate, cis Chemical and Physical Properties

Names and Identifiers

    • cis-tert-Butyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate
    • tert-butyl (1R,6S)-7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate
    • (3R,4S)-1-BOC-3,4-EPOXYPIPERIDINE
    • 3beta,4beta-Epoxypiperidine-1-carboxylic acid tert-butyl ester
    • (1R,6S)-tert-Butyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate
    • tert-butyl (1S,6R)-7-oxa-4-azabicyclo[4.1.0]heptane-4-carboxylate
    • rac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo4.1.0heptane-3-carboxylate, cis
    • MDL： MFCD14582439
    • Inchi： 1S/C10H17NO3/c1-10(2,3)14-9(12)11-5-4-7-8(6-11)13-7/h7-8H,4-6H2,1-3H3/t7-,8+/m0/s1
    • InChI Key： MMPWHAJQEZIIEH-JGVFFNPUSA-N
    • SMILES： O1[C@@H]2CN(C(=O)OC(C)(C)C)CC[C@H]12

Computed Properties

  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 2
  • Complexity: 246
  • XLogP3: 1
  • Topological Polar Surface Area: 42.1

Experimental Properties

  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 272.5±23.0 °C at 760 mmHg
  • Flash Point: 118.6±22.6 °C
  • Vapor Pressure: 0.0±0.6 mmHg at 25°C

rac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo4.1.0heptane-3-carboxylate, cis Security Information

rac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo4.1.0heptane-3-carboxylate, cis Pricemore >>

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rac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo4.1.0heptane-3-carboxylate, cis Related Literature

Additional information on rac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo4.1.0heptane-3-carboxylate, cis

Rac-Tert-Butyl (1R,6S)-7-Oxa-3-Azabicyclo[4.1.0]Heptane-3-Carboxylate, Cis: A Comprehensive Overview

The compoundrac-tert-butyl (1R,6S)-7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate, cis, identified by the CAS numberCAS No: 1268521-10-3, is a highly specialized organic compound with significant applications in the field of pharmaceutical chemistry and related disciplines. This compound has garnered attention due to its unique structural properties and potential therapeutic applications.

Recent studies have highlighted the importance ofbicyclic structures in drug design, particularly those incorporating oxygen and nitrogen atoms within the ring system. The7-oxa and3-aza components of this compound contribute to its distinctive chemical profile, making it a valuable tool in the development of novel pharmaceutical agents.

The synthesis ofrac-tert-butyl (1R,6S)-7-Oxa derivatives has been optimized through advanced methodologies that ensure high yields and stereochemical control. Researchers have employed various strategies, including ring-closing metathesis and asymmetric catalysis, to achieve the desired stereochemistry in this compound.

In terms of applications,cis-configured bicyclic compounds like this one are often utilized as intermediates in the synthesis of bioactive molecules. Their rigid structure provides stability and enhances the molecule's ability to interact with biological targets, such as enzymes or receptors.

Pioneering research has demonstrated that this compound exhibits promising activity in preclinical models of neurological disorders. Its ability to modulate specific ion channels has positioned it as a potential candidate for the development of treatments for conditions such as epilepsy and chronic pain.

The stereochemistry of this compound plays a critical role in its biological activity.(1R,6S) configuration ensures optimal interactions with target proteins, thereby enhancing its therapeutic potential.

In conclusion,CAS No: 1268521-10-3 represents a significant advancement in organic synthesis and drug discovery. Its unique properties and versatile applications underscore its importance in contemporary chemical research.

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