Cas no 126517-23-5 ((2-chlorophenyl)(3-chlorophenyl)methanol)

(2-Chlorophenyl)(3-chlorophenyl)methanol is a bichlorinated benzhydrol derivative with applications in organic synthesis and pharmaceutical intermediates. Its structure, featuring two distinct chlorophenyl groups, enables selective reactivity in cross-coupling reactions and as a precursor for chiral ligands or bioactive molecules. The electron-withdrawing chlorine substituents enhance stability while allowing further functionalization at either aromatic ring. This compound is particularly valuable in asymmetric synthesis due to the potential for stereocontrol at the carbinol center. It is typically supplied as a high-purity solid with consistent lot-to-lot performance, ensuring reproducibility in research and development processes. Proper handling under inert conditions is recommended to preserve its reactivity.
(2-chlorophenyl)(3-chlorophenyl)methanol structure
126517-23-5 structure
Product Name:(2-chlorophenyl)(3-chlorophenyl)methanol
CAS No:126517-23-5
MF:C13H10Cl2O
MW:253.123901844025
MDL:MFCD12780202
CID:1223938
PubChem ID:14417331
Update Time:2025-10-21

(2-chlorophenyl)(3-chlorophenyl)methanol Chemical and Physical Properties

Names and Identifiers

    • Benzenemethanol, 2-chloro-a-(3-chlorophenyl)-
    • BFA51723
    • (2-chlorophenyl)(3-chlorophenyl)methanol
    • CS-0265265
    • (2-chlorophenyl)-(3-chlorophenyl)methanol
    • EN300-97366
    • Z733415304
    • 126517-23-5
    • AKOS010258808
    • G60614
    • MDL: MFCD12780202
    • Inchi: 1S/C13H10Cl2O/c14-10-5-3-4-9(8-10)13(16)11-6-1-2-7-12(11)15/h1-8,13,16H
    • InChI Key: JYOCLXGPKHQPFD-UHFFFAOYSA-N
    • SMILES: ClC1C=CC=CC=1C(C1C=CC=C(C=1)Cl)O

Computed Properties

  • Exact Mass: 252.011
  • Monoisotopic Mass: 252.0108703g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 2
  • Complexity: 222
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 4
  • Topological Polar Surface Area: 20.2?2

Experimental Properties

  • PSA: 20.23

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Additional information on (2-chlorophenyl)(3-chlorophenyl)methanol

Comprehensive Overview of (2-Chlorophenyl)(3-Chlorophenyl)Methanol (CAS No. 126517-23-5)

(2-Chlorophenyl)(3-chlorophenyl)methanol is a specialized organic compound with the CAS registry number 126517-23-5. This compound belongs to the class of diarylmethanols, which are widely studied for their applications in pharmaceuticals, agrochemicals, and material science. The presence of two chlorophenyl groups in its structure enhances its reactivity and makes it a valuable intermediate in synthetic chemistry. Researchers and industries are increasingly interested in this compound due to its potential in developing novel biologically active molecules and advanced materials.

The molecular formula of (2-chlorophenyl)(3-chlorophenyl)methanol is C13H10Cl2O, and its molecular weight is 253.12 g/mol. The compound features a central methanol group flanked by two chlorinated phenyl rings, which contribute to its unique physicochemical properties. These properties include moderate solubility in organic solvents like ethanol, acetone, and dichloromethane, making it suitable for various chemical reactions. Its stability under standard conditions and compatibility with common reagents further enhance its utility in organic synthesis.

In recent years, the demand for chlorinated aromatic compounds like (2-chlorophenyl)(3-chlorophenyl)methanol has surged due to their role in developing pharmaceutical intermediates and specialty chemicals. For instance, this compound is often explored in the synthesis of antimicrobial agents and polymer additives. Its structural motif is also found in several drug candidates undergoing clinical trials, highlighting its significance in modern medicinal chemistry. Users searching for "CAS 126517-23-5 uses" or "diarylmethanol derivatives applications" will find this compound highly relevant to their queries.

From an environmental and safety perspective, (2-chlorophenyl)(3-chlorophenyl)methanol is handled with standard laboratory precautions. While it is not classified as hazardous under typical conditions, proper storage in a cool, dry place away from strong oxidizers is recommended. The compound's eco-friendly synthesis methods are a growing area of research, aligning with the global push toward green chemistry. This aspect is particularly appealing to users searching for "sustainable chemical intermediates" or "green synthesis of chlorinated compounds."

The analytical characterization of CAS 126517-23-5 typically involves techniques such as nuclear magnetic resonance (NMR), mass spectrometry (MS), and high-performance liquid chromatography (HPLC). These methods ensure high purity and confirm the structural integrity of the compound, which is critical for its applications in high-value chemical production. Researchers often look for "NMR data for (2-chlorophenyl)(3-chlorophenyl)methanol" or "HPLC purity standards" to validate their findings.

In summary, (2-chlorophenyl)(3-chlorophenyl)methanol (CAS No. 126517-23-5) is a versatile and valuable compound in synthetic and applied chemistry. Its unique structure, combined with its broad applicability, makes it a subject of ongoing research and industrial interest. Whether for pharmaceutical development, material science, or green chemistry initiatives, this compound continues to attract attention from scientists and manufacturers worldwide.

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