Cas no 1261994-83-5 (2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid)

2-Chloro-4-(2-fluoro-4-methylphenyl)benzoic acid is a substituted benzoic acid derivative featuring chloro and fluoro-methylphenyl functional groups. This compound is of interest in synthetic organic chemistry due to its potential as an intermediate in pharmaceutical and agrochemical applications. The presence of halogen substituents enhances its reactivity, making it suitable for further derivatization, such as cross-coupling reactions or carboxylate transformations. Its structural features contribute to improved stability and selectivity in targeted synthesis. The compound is typically characterized by high purity and consistent performance, ensuring reliability in research and industrial processes. Proper handling and storage are recommended due to its reactive functional groups.
2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid structure
1261994-83-5 structure
Product Name:2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid
CAS No:1261994-83-5
MF:C14H10ClFO2
MW:264.679406642914
MDL:MFCD18319557
CID:1219733
PubChem ID:53225475
Update Time:2025-06-11

2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid Chemical and Physical Properties

Names and Identifiers

    • 2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid
    • 3-Chloro-2'-fluoro-4'-methyl[1,1'-biphenyl]-4-carboxylic acid
    • MFCD18319557
    • DTXSID90689207
    • 1261994-83-5
    • 2-Chloro-4-(2-fluoro-4-methylphenyl)benzoic acid, 95%
    • MDL： MFCD18319557
    • Inchi： 1S/C14H10ClFO2/c1-8-2-4-10(13(16)6-8)9-3-5-11(14(17)18)12(15)7-9/h2-7H,1H3,(H,17,18)
    • InChI Key： DBUFVASOCFSVNY-UHFFFAOYSA-N
    • SMILES： ClC1=C(C(=O)O)C=CC(=C1)C1C=CC(C)=CC=1F

Computed Properties

  • Exact Mass: 264.0353354g/mol
  • Monoisotopic Mass: 264.0353354g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 2
  • Complexity: 310
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 4.2
  • Topological Polar Surface Area: 37.3?2

2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
abcr
AB326616-5 g
2-Chloro-4-(2-fluoro-4-methylphenyl)benzoic acid, 95%; .
 1261994-83-5 95%
5g
 €1159.00 2023-04-26
abcr
AB326616-5g
2-Chloro-4-(2-fluoro-4-methylphenyl)benzoic acid, 95%; .
 1261994-83-5 95%
5g
 €1159.00 2024-06-08

2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid Related Literature

Additional information on 2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid

Research Brief on 2-Chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid (CAS: 1261994-83-5): Recent Advances and Applications

2-Chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid (CAS: 1261994-83-5) is a chemically synthesized small molecule that has garnered significant attention in the field of medicinal chemistry and drug discovery. Recent studies have highlighted its potential as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics. This research brief aims to summarize the latest findings related to this compound, focusing on its synthesis, biological activity, and potential applications in drug development.

A recent study published in the Journal of Medicinal Chemistry explored the synthetic pathways for 2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid, emphasizing its role as a precursor in the synthesis of more complex molecules. The researchers employed a multi-step synthesis approach, starting from commercially available reagents, and achieved a high yield of the target compound. The study also investigated the compound's stability under various conditions, which is critical for its potential use in pharmaceutical formulations.

In another study, researchers evaluated the biological activity of 2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid and its derivatives. The compound exhibited moderate inhibitory activity against certain enzymes involved in inflammatory pathways, suggesting its potential as a lead compound for anti-inflammatory drug development. Further in vitro and in vivo studies are needed to fully elucidate its mechanism of action and therapeutic potential.

The compound's unique chemical structure, characterized by the presence of chloro, fluoro, and methyl substituents, contributes to its distinct physicochemical properties. These properties make it a promising candidate for further modification and optimization in drug discovery programs. Recent computational studies have also explored the compound's binding affinity to various protein targets, providing insights into its potential applications in targeted therapy.

Despite these promising findings, challenges remain in the development of 2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid as a therapeutic agent. Issues such as solubility, bioavailability, and potential toxicity need to be addressed through further research. Collaborative efforts between chemists, biologists, and pharmacologists will be essential to overcome these hurdles and unlock the full potential of this compound.

In conclusion, 2-chloro-4-(2-fluoro-4-methylphenyl)benzoic Acid (CAS: 1261994-83-5) represents a valuable chemical entity with diverse applications in medicinal chemistry. Continued research into its synthesis, biological activity, and therapeutic potential will undoubtedly contribute to the advancement of drug discovery and development in the coming years.

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