Cas no 1261970-35-7 (2-nitro-4-[4-(trifluoromethyl)phenyl]phenol)

2-Nitro-4-[4-(trifluoromethyl)phenyl]phenol is a specialized aromatic compound featuring a nitro group and a trifluoromethylphenyl substituent on a phenolic scaffold. Its unique structure imparts distinct electronic and steric properties, making it valuable in synthetic chemistry, particularly as an intermediate in the preparation of pharmaceuticals, agrochemicals, and advanced materials. The presence of the electron-withdrawing nitro and trifluoromethyl groups enhances reactivity in electrophilic and nucleophilic substitution reactions. This compound exhibits good stability under standard conditions, facilitating handling and storage. Its structural motifs are often leveraged in the development of bioactive molecules, where the trifluoromethyl group can improve metabolic stability and lipophilicity. Suitable for controlled functionalization, it serves as a versatile building block in organic synthesis.

2-nitro-4-[4-(trifluoromethyl)phenyl]phenol structure

1261970-35-7 structure

Product Name:2-nitro-4-[4-(trifluoromethyl)phenyl]phenol

CAS No:1261970-35-7

MF:C₁₃H₈F₃NO₃

MW:283.20273399353

MDL:MFCD18315969

CID:1219747

PubChem ID:53221695

Update Time:2025-06-11

2-nitro-4-[4-(trifluoromethyl)phenyl]phenol Chemical and Physical Properties

Names and Identifiers

- 2-nitro-4-[4-(trifluoromethyl)phenyl]phenol
- 3-Nitro-4'-(trifluoromethyl)[1,1'-biphenyl]-4-ol
- 2-Nitro-4-(4-trifluoromethylphenyl)phenol, 95%
- 2-NITRO-4-(4-TRIFLUOROMETHYLPHENYL)PHENOL
- MFCD18315969
- DTXSID20686305
- A1-69647
- 3-Nitro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-ol
- 1261970-35-7
- MDL： MFCD18315969
- Inchi： 1S/C13H8F3NO3/c14-13(15,16)10-4-1-8(2-5-10)9-3-6-12(18)11(7-9)17(19)20/h1-7,18H
- InChI Key： IJQJHTSXWZTNDV-UHFFFAOYSA-N
- SMILES： FC(C1C=CC(=CC=1)C1C=CC(=C(C=1)[N+](=O)[O-])O)(F)F

Computed Properties

Exact Mass: 283.04562760g/mol
Monoisotopic Mass: 283.04562760g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 6
Heavy Atom Count: 20
Rotatable Bond Count: 1
Complexity: 348
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 4.6
Topological Polar Surface Area: 66?2

2-nitro-4-[4-(trifluoromethyl)phenyl]phenol Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time	Inquiry
abcr	AB322176-5 g	2-Nitro-4-(4-trifluoromethylphenyl)phenol, 95%; .	1261970-35-7	95%	5g	€1159.00	2023-04-26
abcr	AB322176-5g	2-Nitro-4-(4-trifluoromethylphenyl)phenol, 95%; .	1261970-35-7	95%	5g	€1159.00	2025-02-12

2-nitro-4-[4-(trifluoromethyl)phenyl]phenol Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:1261970-35-7)2-nitro-4-[4-(trifluoromethyl)phenyl]phenol

Order Number:A1122047

Stock Status:in Stock

Quantity:5g

Purity:99%

Pricing Information Last Updated:Thursday, 29 August 2024 21:29

Price ($):687.0

Email:[email protected]

Product Official Link

2-nitro-4-[4-(trifluoromethyl)phenyl]phenol Related Literature

1. Excited state dynamics of symmetric and asymmetric Cr3(dpa)4Cl2 measured using femtosecond transient absorption spectroscopy?

Chao-Han Cheng,Wen-Zhen Wang,Shie-Ming Peng,I-Chia Chen Phys. Chem. Chem. Phys., 2017,19, 25471-25477
2. Excited-state proton-coupled electron transfer within ion pairs?

Gerald J. Meyer,Leif Hammarstr?m Chem. Sci., 2020,11, 3460-3473
3. Excitonic channels from bio-inspired templated supramolecular assembly of J-aggregate nanowires?

Daniel Messmer,Stefan Salentinig,Jakob Heier Nanoscale, 2019,11, 6929-6938
4. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?

Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
5. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?

Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526

Additional information on 2-nitro-4-[4-(trifluoromethyl)phenyl]phenol

Professional Introduction to Compound with CAS No. 1261970-35-7 and Product Name: 2-nitro-4-[4-(trifluoromethyl)phenyl]phenol

The compound with the CAS number 1261970-35-7 and the product name 2-nitro-4-[4-(trifluoromethyl)phenyl]phenol represents a significant advancement in the field of pharmaceutical chemistry. This compound, characterized by its nitro and trifluoromethyl substituents, has garnered attention for its potential applications in medicinal chemistry and drug discovery. The structural features of this molecule contribute to its unique chemical properties, making it a valuable candidate for further investigation.

One of the most striking aspects of 2-nitro-4-[4-(trifluoromethyl)phenyl]phenol is its molecular architecture, which includes both electron-withdrawing and electron-donating groups. The nitro group at the 2-position introduces a strong electron-withdrawing effect, while the trifluoromethyl group at the 4-position of the phenyl ring enhances lipophilicity and metabolic stability. This combination of functional groups makes the compound highly versatile and suitable for various biochemical interactions.

Recent research in the field of medicinal chemistry has highlighted the importance of nitroaromatic compounds in drug development. The nitro group in 2-nitro-4-[4-(trifluoromethyl)phenyl]phenol can be reduced to an amine, a transformation that is often exploited in medicinal chemistry to introduce new pharmacological activities. This reactivity makes the compound a promising scaffold for designing novel therapeutic agents.

The presence of the trifluoromethyl group in the molecule also contributes to its pharmacological profile. Trifluoromethyl groups are known to increase metabolic stability and binding affinity, making them a favored substituent in many drug candidates. In 2-nitro-4-[4-(trifluoromethyl)phenyl]phenol, this group enhances the compound's ability to interact with biological targets, thereby improving its potential as a therapeutic agent.

Current studies are exploring the biological activity of 2-nitro-4-[4-(trifluoromethyl)phenyl]phenol in various disease models. Preliminary findings suggest that this compound exhibits inhibitory activity against certain enzymes and receptors, which could be relevant for treating conditions such as inflammation and cancer. The nitro group's ability to participate in redox reactions further adds to its potential as a bioactive molecule.

The synthesis of 2-nitro-4-[4-(trifluoromethyl)phenyl]phenol involves multi-step organic reactions, including nitration and cross-coupling techniques. The synthesis route has been optimized to ensure high yield and purity, making it feasible for large-scale production. Advanced spectroscopic techniques such as NMR and mass spectrometry have been employed to confirm the structural integrity of the compound.

In conclusion, 2-nitro-4-[4-(trifluoromethyl)phenyl]phenol (CAS No. 1261970-35-7) is a structurally intriguing compound with significant potential in pharmaceutical applications. Its unique combination of functional groups and favorable chemical properties make it an attractive candidate for further research and development. As our understanding of molecular interactions continues to evolve, compounds like this are poised to play a crucial role in the discovery of new therapies.

1261970-35-7 (2-nitro-4-[4-(trifluoromethyl)phenyl]phenol) Related Products

Recommended suppliers