Cas no 1261923-01-6 (4-(3-Methoxyphenyl)-2-nitrophenol)

4-(3-Methoxyphenyl)-2-nitrophenol is a nitrophenol derivative featuring a methoxy-substituted phenyl group at the para position relative to the hydroxyl group. This compound is of interest in organic synthesis and pharmaceutical research due to its unique structural properties, which facilitate its use as an intermediate in the preparation of more complex molecules. The presence of both nitro and hydroxyl groups enhances its reactivity, making it suitable for further functionalization. Its methoxy substituent contributes to electronic modulation, influencing solubility and stability. This compound is typically handled under controlled conditions due to its potential sensitivity. High-purity grades are available for research applications requiring precise chemical characteristics.
4-(3-Methoxyphenyl)-2-nitrophenol structure
1261923-01-6 structure
Product Name:4-(3-Methoxyphenyl)-2-nitrophenol
CAS No:1261923-01-6
MF:C13H11NO4
MW:245.230743646622
MDL:MFCD18315889
CID:2763718
PubChem ID:53221620
Update Time:2025-06-13

4-(3-Methoxyphenyl)-2-nitrophenol Chemical and Physical Properties

Names and Identifiers

    • 3'-Methoxy-3-nitro[1,1'-biphenyl]-4-ol
    • A1-69635
    • 3'-Methoxy-3-nitro-[1,1'-biphenyl]-4-ol
    • 4-(3-METHOXYPHENYL)-2-NITROPHENOL
    • 4-(3-Methoxyphenyl)-2-nitrophenol, 95%
    • 1261923-01-6
    • DTXSID50686237
    • MFCD18315889
    • 4-(3-Methoxyphenyl)-2-nitrophenol
    • MDL: MFCD18315889
    • Inchi: 1S/C13H11NO4/c1-18-11-4-2-3-9(7-11)10-5-6-13(15)12(8-10)14(16)17/h2-8,15H,1H3
    • InChI Key: QMHHQOSZBPFBCK-UHFFFAOYSA-N
    • SMILES: O(C)C1=CC=CC(=C1)C1C=CC(=C(C=1)[N+](=O)[O-])O

Computed Properties

  • Exact Mass: 245.06880783Da
  • Monoisotopic Mass: 245.06880783Da
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 2
  • Complexity: 291
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.7
  • Topological Polar Surface Area: 75.3?2

4-(3-Methoxyphenyl)-2-nitrophenol Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
abcr
AB322095-5 g
4-(3-Methoxyphenyl)-2-nitrophenol, 95%; .
1261923-01-6 95%
5g
€1159.00 2023-05-19
abcr
AB322095-5g
4-(3-Methoxyphenyl)-2-nitrophenol, 95%; .
1261923-01-6 95%
5g
€1159.00 2025-02-21

Additional information on 4-(3-Methoxyphenyl)-2-nitrophenol

Comprehensive Analysis of 4-(3-Methoxyphenyl)-2-nitrophenol (CAS No. 1261923-01-6): Properties, Applications, and Industry Trends

4-(3-Methoxyphenyl)-2-nitrophenol (CAS No. 1261923-01-6) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research due to its unique structural features. As a nitrophenol derivative, it combines a methoxy group and a nitro group on a phenolic backbone, making it a versatile intermediate for synthesizing complex molecules. Recent studies highlight its potential in drug discovery, particularly in targeting enzymes involved in inflammatory pathways, aligning with the growing demand for precision medicine solutions.

The compound’s molecular structure (C13H11NO4) contributes to its moderate polarity, which influences its solubility in organic solvents like ethanol and dimethyl sulfoxide (DMSO). Researchers emphasize its role in high-throughput screening assays, where its chromophoric properties enable UV-Vis detection. With the rise of AI-driven molecular design, 1261923-01-6 has been explored in cheminformatics databases as a scaffold for bioactive molecules, addressing trending queries about “nitrophenol applications in drug development” and “methoxy-substituted phenol derivatives.”

In industrial contexts, 4-(3-Methoxyphenyl)-2-nitrophenol is valued for its utility in fine chemical synthesis. Its electron-withdrawing nitro group facilitates reactions such as nucleophilic aromatic substitution, a process critical for producing agrochemicals and dye intermediates. Sustainability-focused innovations have also spotlighted its potential in green chemistry, with patents describing catalytic methods to reduce waste during its production—a response to the surge in searches for “eco-friendly chemical synthesis.”

From a regulatory perspective, CAS 1261923-01-6 is not classified as hazardous under major chemical inventories, making it accessible for research. However, proper handling protocols are recommended due to its nitroaromatic nature. Analytical techniques like HPLC and LC-MS are commonly employed for purity verification, reflecting industry standards for quality control—a topic frequently searched alongside “nitrophenol characterization methods.”

Emerging trends link 4-(3-Methoxyphenyl)-2-nitrophenol to cancer research, where its derivatives are investigated for kinase inhibition. Public datasets, such as those from the NIH, cite its relevance in structure-activity relationship (SAR) studies, coinciding with rising interest in “small-molecule therapeutics.” Additionally, its photostability makes it a candidate for optical materials, tapping into the booming optoelectronics market.

In summary, 1261923-01-6 exemplifies the intersection of traditional chemistry and cutting-edge applications. Its adaptability across pharmaceuticals, materials science, and sustainable chemistry ensures its continued relevance, while SEO-optimized terms like “nitrophenol synthesis guide” and “methoxyphenol uses” reflect its digital footprint. As research evolves, this compound is poised to address both scientific and industrial challenges.

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