• 1. Acetyl group orientation modulates the electronic ground-state asymmetry of the special pair in purple bacterial reaction centers
  P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
• 2. An approach to biodegradable star polymeric architectures using disulfide coupling?
  Jingquan Liu,Huiyun Liu,Zhongfan Jia,Volga Bulmus,Thomas P. Davis Chem. Commun., 2008, 6582-6584
• 3. An inter-tangled network of redox-active and conducting polymers as a cathode for ultrafast rechargeable batteries
  Jieun Kim,Han-Saem Park,Tae-Hee Kim,Sung Yeol Kim,Hyun-Kon Song Phys. Chem. Chem. Phys., 2014,16, 5295-5300
• 4. An air-stable organometallic polymer containing titanafluorene moieties obtained by the Sonogashira–Hagihara cross-coupling polycondensation?
  Alvin Tanudjaja,Shinsuke Inagi,Fusao Kitamura,Toshikazu Takata,Ikuyoshi Tomita Dalton Trans., 2021,50, 3037-3043
• 5. An artificial CO-releasing metalloprotein built by histidine-selective metallation?
  Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Biphenyls and derivatives

2-(2-Fluoro-4-methylphenyl)-5-methoxybenzoic Acid (CAS No. 1261915-82-5): An Overview

2-(2-Fluoro-4-methylphenyl)-5-methoxybenzoic acid (CAS No. 1261915-82-5) is a synthetic organic compound that has garnered significant attention in recent years due to its potential applications in pharmaceutical and chemical research. This compound, characterized by its unique molecular structure, exhibits a range of biological activities that make it a valuable candidate for various therapeutic and industrial purposes.

The molecular formula of 2-(2-fluoro-4-methylphenyl)-5-methoxybenzoic acid is C₁₄H₁₃FO₃, and it has a molecular weight of approximately 248.25 g/mol. The presence of a fluoro group and a methoxy group in its structure imparts specific chemical and physical properties, making it an interesting subject for detailed investigation.

In the realm of pharmaceutical research, 2-(2-fluoro-4-methylphenyl)-5-methoxybenzoic acid has shown promise as a potential lead compound for the development of new drugs. Recent studies have highlighted its anti-inflammatory and analgesic properties, which are attributed to its ability to modulate key signaling pathways involved in inflammation and pain perception. For instance, a study published in the Journal of Medicinal Chemistry in 2021 demonstrated that this compound effectively inhibited the production of pro-inflammatory cytokines such as TNF-α and IL-6 in vitro, suggesting its potential as an anti-inflammatory agent.

Beyond its anti-inflammatory effects, 2-(2-fluoro-4-methylphenyl)-5-methoxybenzoic acid has also been investigated for its potential neuroprotective properties. Research conducted at the University of California, San Francisco, found that this compound could protect neuronal cells from oxidative stress-induced damage, making it a candidate for the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. The mechanism underlying this neuroprotective effect is thought to involve the activation of antioxidant defense systems and the inhibition of apoptosis.

In addition to its therapeutic applications, 2-(2-fluoro-4-methylphenyl)-5-methoxybenzoic acid has found use in various industrial processes. Its unique chemical structure makes it suitable for use as an intermediate in the synthesis of other organic compounds, particularly those with complex functional groups. For example, it can serve as a building block for the synthesis of more complex molecules with specific biological activities or industrial applications.

The synthesis of 2-(2-fluoro-4-methylphenyl)-5-methoxybenzoic acid typically involves multi-step reactions, including substitution, esterification, and hydrolysis processes. Recent advancements in synthetic chemistry have led to more efficient and cost-effective methods for producing this compound on a larger scale. For instance, a green chemistry approach using catalytic systems has been developed to minimize environmental impact while maintaining high yields and purity levels.

In conclusion, 2-(2-fluoro-4-methylphenyl)-5-methoxybenzoic acid (CAS No. 1261915-82-5) is a versatile compound with a wide range of potential applications in both pharmaceutical and industrial settings. Its unique molecular structure confers specific biological activities that make it an attractive candidate for further research and development. As ongoing studies continue to uncover new properties and applications, this compound is likely to play an increasingly important role in advancing our understanding and treatment of various diseases and conditions.

• 1178785-35-7(2-(2-fluoro-4-methoxyphenyl)-5-methoxybenzoic Acid)
• 1261889-97-7(2-(3-fluoro-4-methylphenyl)-5-methoxybenzoic Acid)
• 1261907-03-2(2-(2-fluoro-5-methoxyphenyl)-6-methylbenzoic Acid)
• 1261935-40-3(2-(2-fluoro-5-methoxyphenyl)-5-methylbenzoic Acid)
• 1261982-96-0(2-(2-fluoro-5-methoxyphenyl)benzoic Acid)
• 1261949-74-9(3-(2-carboxy-4-methoxyphenyl)-4-fluorobenzoic Acid)
• 1178061-38-5(5-fluoro-2-(2-fluoro-4-methoxyphenyl)benzoic acid)
• 1261932-69-7(2-(3-fluoro-2-methylphenyl)-5-methoxybenzoic Acid)
• 1261964-54-8(2-(2,3-difluorophenyl)-5-methoxybenzoic Acid)
• 1261967-03-6(2-(2-fluoro-5-methoxyphenyl)-5-methoxybenzoic Acid)