Cas no 1261915-69-8 (2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid)

2-Chloro-4-[3-(hydroxymethyl)phenyl]benzoic acid is a versatile intermediate in organic synthesis, particularly valuable for pharmaceutical and agrochemical applications. Its structure combines a chlorinated benzoic acid core with a hydroxymethyl-substituted phenyl group, offering dual reactivity for further functionalization. The carboxylic acid moiety enables esterification or amidation, while the hydroxymethyl group provides a handle for etherification or oxidation. This compound exhibits high purity and stability under standard conditions, making it suitable for precision reactions. Its balanced polarity ensures good solubility in common organic solvents, facilitating downstream processing. Researchers appreciate its reliability in constructing complex molecular architectures, particularly in medicinal chemistry where such scaffolds are prevalent in bioactive molecules.
2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid structure
1261915-69-8 structure
Product Name:2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid
CAS No:1261915-69-8
MF:C14H11ClO3
MW:262.688343286514
MDL:MFCD18319435
CID:1219211
PubChem ID:53225355
Update Time:2025-05-23

2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid Chemical and Physical Properties

Names and Identifiers

    • 2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid
    • 3-Chloro-3'-(hydroxymethyl)[1,1'-biphenyl]-4-carboxylic acid
    • 2-Chloro-4-(3-hydroxymethylphenyl)benzoic acid, 95%
    • DTXSID10689087
    • 2-CHLORO-4-(3-HYDROXYMETHYLPHENYL)BENZOIC ACID
    • 1261915-69-8
    • MFCD18319435
    • MDL： MFCD18319435
    • Inchi： 1S/C14H11ClO3/c15-13-7-11(4-5-12(13)14(17)18)10-3-1-2-9(6-10)8-16/h1-7,16H,8H2,(H,17,18)
    • InChI Key： OBLPHJSNJXSACD-UHFFFAOYSA-N
    • SMILES： ClC1=C(C(=O)O)C=CC(=C1)C1C=CC=C(CO)C=1

Computed Properties

  • Exact Mass: 262.04
  • Monoisotopic Mass: 262.04
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 3
  • Complexity: 295
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 57.5A^2
  • XLogP3: 2.8

2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
abcr
AB326461-5 g
2-Chloro-4-(3-hydroxymethylphenyl)benzoic acid, 95%; .
 1261915-69-8 95%
5g
 €1159.00 2023-04-26
abcr
AB326461-5g
2-Chloro-4-(3-hydroxymethylphenyl)benzoic acid, 95%; .
 1261915-69-8 95%
5g
 €1159.00 2024-06-08

2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid Related Literature

Additional information on 2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid

Research Briefing on 2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid (CAS: 1261915-69-8)

2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid (CAS: 1261915-69-8) is a chemical compound of significant interest in the field of chemical biology and pharmaceutical research. This compound, characterized by its benzoic acid core substituted with a hydroxymethylphenyl and chloro group, has been the subject of recent investigations due to its potential applications in drug discovery and development. The unique structural features of this molecule make it a promising candidate for further exploration in medicinal chemistry.

Recent studies have focused on the synthesis and characterization of 2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid, with particular attention to its physicochemical properties and biological activity. Researchers have employed advanced spectroscopic techniques, including NMR and mass spectrometry, to confirm the structure and purity of the compound. These studies have laid the groundwork for understanding its potential interactions with biological targets.

In the context of drug discovery, 2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid has shown promise as a building block for the development of novel therapeutic agents. Its structural motif is particularly relevant in the design of small molecule inhibitors targeting various enzymes and receptors. Recent publications have highlighted its utility in the synthesis of compounds with potential anti-inflammatory and anticancer properties.

One of the key areas of investigation has been the compound's role in modulating specific biological pathways. Preliminary in vitro studies suggest that derivatives of 2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid may interact with certain protein targets involved in cellular signaling. These findings have sparked interest in further exploring its mechanism of action and therapeutic potential.

The compound's chemical stability and solubility profile have also been subjects of recent research. Understanding these properties is crucial for its potential formulation into drug products. Studies have examined its behavior under various pH conditions and its compatibility with common pharmaceutical excipients.

From a synthetic chemistry perspective, recent work has focused on optimizing the production of 2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid, with emphasis on yield improvement and purity enhancement. New catalytic methods and green chemistry approaches have been explored to make the synthesis more efficient and environmentally friendly.

As research progresses, the compound's potential applications continue to expand. Current investigations are exploring its use in combination therapies and as a scaffold for developing targeted drug delivery systems. The unique combination of its chemical properties makes it particularly interesting for these applications.

In conclusion, 2-chloro-4-[3-(hydroxymethyl)phenyl]benzoic Acid (CAS: 1261915-69-8) represents an important compound in contemporary chemical biology research. Its diverse potential applications and interesting chemical properties warrant continued investigation. Future research directions may include more extensive biological testing, structure-activity relationship studies, and exploration of novel derivatives with enhanced pharmacological properties.

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