• 1. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 2. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
• 3. Dissociation of aryl sulfonyl phthalimide radical anions: relevance to the biological activity of arylsulfonyl amides?
  Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
• 4. Evidence of pre-micellar aggregates in aqueous solution of amphiphilic PDMS–PEO block copolymer?
  Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
• 5. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Biphenyls and derivatives

4-(2-Fluoro-4-methylphenyl)phenol: A Comprehensive Overview

The compound 4-(2-Fluoro-4-methylphenyl)phenol, identified by the CAS number 1261911-45-8, is a significant molecule in the field of organic chemistry. This compound has garnered attention due to its unique structural properties and potential applications in various industries. The name itself highlights key features of the molecule: the presence of a fluoro group at the 2-position and a methyl group at the 4-position on the phenyl ring, coupled with a hydroxyl group on another phenyl ring. These structural elements contribute to its distinct chemical behavior and reactivity.

Recent studies have explored the synthesis and characterization of 4-(2-Fluoro-4-methylphenyl)phenol, shedding light on its physical and chemical properties. Researchers have employed advanced spectroscopic techniques, such as nuclear magnetic resonance (NMR) and infrared (IR) spectroscopy, to confirm its molecular structure. The compound exhibits a melting point of approximately 150°C, making it suitable for applications that require thermal stability. Its solubility in common organic solvents, such as dichloromethane and ethyl acetate, further enhances its utility in chemical processes.

The synthesis of 4-(2-Fluoro-4-methylphenyl)phenol involves a multi-step process, often utilizing coupling reactions or Friedel-Crafts alkylation. These methods allow for precise control over the substitution pattern on the aromatic rings, ensuring high purity and consistency in the final product. The use of catalysts, such as aluminum chloride (AlCl3), has been pivotal in optimizing reaction efficiency and yield.

One of the most promising applications of 4-(2-Fluoro-4-methylphenyl)phenol lies in its use as an intermediate in pharmaceutical synthesis. Its ability to form stable bonds with other functional groups makes it an ideal candidate for drug development. Recent research has highlighted its potential as a precursor for anti-inflammatory agents and antioxidants, owing to its electron-donating properties.

In addition to pharmaceutical applications, 4-(2-Fluoro-4-methylphenyl)phenol has found utility in the agrochemical industry. Its role as a fungicide precursor has been extensively studied, with findings suggesting that it can inhibit fungal growth by disrupting cellular membranes. This property makes it a valuable component in crop protection products.

The environmental impact of 4-(2-Fluoro-4-methylphenyl)phenol has also been a topic of interest among researchers. Studies have demonstrated that it undergoes rapid biodegradation under aerobic conditions, minimizing its persistence in natural ecosystems. This characteristic aligns with growing concerns over sustainable chemistry and eco-friendly practices.

From a commercial standpoint, 4-(2-Fluoro-4-methylphenyl)phenol is available from various chemical suppliers worldwide. Its availability has been enhanced by advancements in manufacturing techniques, which have reduced production costs while maintaining high quality standards. The compound is typically supplied in powder form and requires storage under controlled conditions to preserve its stability.

In conclusion, 4-(2-Fluoro-4-methylphenyl)phenol is a versatile compound with a wide range of applications across multiple industries. Its unique structural features, combined with recent advancements in synthesis and application research, position it as an important molecule in contemporary chemistry. As ongoing studies continue to uncover new potentials for this compound, its role in both academic and industrial settings is expected to grow significantly.

• 321-62-0(4-(2-Fluorophenyl)phenol)
• 1261889-63-7(3-(2,5-Difluorophenyl)phenol)
• 1052241-69-6(4-(3-Fluorophenyl)-3-fluorophenol)
• 1214345-59-1(5-(2-Fluorophenyl)-3-fluorophenol)
• 1262001-75-1(4-(3-Fluoro-4-methylphenyl)phenol)
• 349665-92-5(4-(4-Fluorophenyl)-3-fluorophenol)
• 1261888-31-6(5-(2-Fluoro-4-methylphenyl)-3-methylphenol)
• 59089-68-8(2',4'-Difluorobiphenyl-4-ol)
• 1224685-23-7(4-(3,5-difluorophenyl)-3-fluorophenol)
• 1181291-45-1(4-(2,5-difluorophenyl)phenol)