• 1. Fe3O4@PANI: a magnetic polyaniline nanomaterial for highly efficient and handy enrichment of intact N-glycopeptides??
  Zhizhen Lai,Mo Zhang,Jinyu Zhou,Tianjing Chen,Dan Li,Xuejing Shen,Jia Liu,Jiang Zhou,Zhili Li Analyst, 2021,146, 4261-4267
• 2. Fe3O4 nanoparticle chains with N-doped carbon coating: magnetotactic bacteria assisted synthesis and high-rate lithium storage?
  Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
• 3. Exciplex emission from the mixed dimer of naphthalene and 2-cyanonaphthalene in a supersonic jet
  Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
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  Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Biphenyls and derivatives

Comprehensive Overview of 4-(4-Fluoro-3-methoxyphenyl)-3-methoxybenzoic acid (CAS No. 1261907-29-2)

4-(4-Fluoro-3-methoxyphenyl)-3-methoxybenzoic acid (CAS No. 1261907-29-2) is a fluorinated aromatic compound with significant potential in pharmaceutical and material science applications. This methoxybenzoic acid derivative features a unique structural framework, combining a fluorophenyl moiety with a methoxy-substituted benzoic acid group. Its molecular formula, C₁₅H₁₃FO₄, and precise weight of 276.26 g/mol make it a subject of interest for researchers exploring small-molecule drug candidates and organic synthesis intermediates.

The compound's dual methoxy groups and fluorine atom contribute to its electronic properties, enhancing its utility in medicinal chemistry. Recent studies highlight its relevance in targeting enzyme inhibition, particularly in inflammation-related pathways, aligning with the growing demand for anti-inflammatory agents. Users frequently search for "fluorinated benzoic acid applications" or "methoxy-phenyl derivatives in drug discovery," reflecting its interdisciplinary importance.

From a synthetic perspective, CAS 1261907-29-2 is often synthesized via cross-coupling reactions, such as Suzuki-Miyaura couplings, to introduce the 4-fluoro-3-methoxyphenyl group. This method is favored for its high yield and compatibility with green chemistry principles, a trending topic in sustainable synthesis. Analytical techniques like HPLC and NMR are critical for purity verification, addressing common queries like "how to characterize fluorinated aromatic compounds."

In material science, this compound's aromatic stacking capability makes it a candidate for organic semiconductors or liquid crystal displays (LCDs). Its thermal stability and solubility profile are frequently discussed in forums on "advanced organic materials." Researchers also explore its photophysical properties for potential use in OLEDs, responding to the surge in demand for energy-efficient displays.

Regulatory and safety data for 4-(4-Fluoro-3-methoxyphenyl)-3-methoxybenzoic acid emphasize its non-hazardous classification under standard handling conditions. However, proper personal protective equipment (PPE) is recommended during lab use, a point often raised in "safe handling of fluorinated compounds" searches. Storage should be in a cool, dry environment to preserve stability.

The compound's patent landscape reveals applications in kinase inhibitor formulations, tying into the booming cancer therapeutics market. Queries like "fluorine in drug design" or "benzoic acid derivatives for targeted therapy" underscore its relevance. Future research may focus on its bioavailability optimization and structure-activity relationships (SAR), key themes in precision medicine discussions.

In summary, CAS 1261907-29-2 exemplifies the intersection of fluorine chemistry and functional material design. Its versatility addresses both current industrial needs and emerging scientific challenges, making it a compound of enduring interest across multiple high-growth sectors.

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