Cas no 1261903-70-1 (4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid)

4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid is a fluorinated phenolic benzoic acid derivative with potential applications in pharmaceutical and chemical research. Its structure features both hydroxyl and carboxylic acid functional groups, offering reactivity for further derivatization or coordination chemistry. The fluorine substitution enhances metabolic stability and bioavailability, making it a valuable intermediate in drug discovery. The compound’s dual hydroxyl groups provide sites for selective modifications, while the aromatic framework ensures structural rigidity. Its well-defined synthesis route allows for high purity, critical for precise experimental outcomes. This compound is particularly useful in developing enzyme inhibitors or fluorescent probes due to its electronic properties.
4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid structure
1261903-70-1 structure
Product Name:4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid
CAS No:1261903-70-1
MF:C13H9FO4
MW:248.206567525864
MDL:MFCD18319707
CID:2762428
PubChem ID:53225625
Update Time:2025-05-20

4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid Chemical and Physical Properties

Names and Identifiers

    • 1261903-70-1
    • 4-(3-FLUORO-4-HYDROXYPHENYL)-2-HYDROXYBENZOIC ACID
    • 3'-Fluoro-3,4'-dihydroxy[1,1'-biphenyl]-4-carboxylic acid
    • DTXSID80689357
    • MFCD18319707
    • 4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid, 95%
    • 4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid
    • MDL: MFCD18319707
    • Inchi: 1S/C13H9FO4/c14-10-5-7(2-4-11(10)15)8-1-3-9(13(17)18)12(16)6-8/h1-6,15-16H,(H,17,18)
    • InChI Key: JYUXJAVXQBOJQQ-UHFFFAOYSA-N
    • SMILES: FC1=C(C=CC(=C1)C1C=CC(C(=O)O)=C(C=1)O)O

Computed Properties

  • Exact Mass: 248.04848693Da
  • Monoisotopic Mass: 248.04848693Da
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 2
  • Complexity: 309
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 4
  • Topological Polar Surface Area: 77.8?2

4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
abcr
AB326787-5g
4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid, 95%; .
1261903-70-1 95%
5g
€1159.00 2025-04-21
abcr
AB326787-5 g
4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid, 95%; .
1261903-70-1 95%
5g
€1159.00 2023-04-26

Additional information on 4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid

4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic Acid: A Comprehensive Overview

The compound 4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid, with CAS No. 1261903-70-1, is a fascinating organic molecule that has garnered significant attention in the fields of pharmaceutical chemistry and materials science. This compound is characterized by its unique structure, which includes a benzoic acid moiety substituted with a hydroxyl group at the 2-position and a 3-fluoro-4-hydroxyphenyl group at the 4-position. The presence of both hydroxyl and fluoro groups introduces interesting electronic and steric effects, making this compound a valuable subject for further research.

Recent studies have highlighted the potential of 4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid in the development of novel drugs targeting neurodegenerative diseases. Researchers have explored its ability to modulate key enzymes involved in pathways associated with Alzheimer's disease and Parkinson's disease. The compound's hydroxyl groups play a crucial role in its bioavailability and interaction with biological systems, making it a promising candidate for further preclinical studies.

In addition to its pharmacological applications, this compound has also been investigated for its potential use in material science. Its aromatic structure and functional groups make it suitable for applications in organic electronics, particularly as a component in semiconducting materials. Recent advancements in this area have demonstrated that derivatives of this compound can exhibit desirable electronic properties, such as high electron mobility, which could be leveraged in the development of next-generation electronic devices.

The synthesis of 4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid involves a multi-step process that typically begins with the preparation of the corresponding phenol derivative. This is followed by nucleophilic substitution or coupling reactions to introduce the fluoro group at the desired position. The final step involves oxidation or hydrolysis to introduce the carboxylic acid group. Researchers have optimized these steps to achieve high yields and purity, ensuring that the compound meets the stringent requirements of modern pharmaceutical and materials applications.

From an environmental perspective, the biodegradability and eco-friendliness of this compound have also been studied. Initial findings suggest that it exhibits moderate biodegradability under aerobic conditions, which is an important consideration for its large-scale production and use. However, further research is needed to fully understand its environmental impact and to develop sustainable production methods.

In conclusion, 4-(3-Fluoro-4-hydroxyphenyl)-2-hydroxybenzoic acid is a versatile compound with significant potential across multiple disciplines. Its unique structure, combined with recent advancements in synthesis and application studies, positions it as a key molecule for future research and development. As ongoing studies continue to uncover new insights into its properties and uses, this compound is poised to make meaningful contributions to both medicine and materials science.

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