• 1. An apparatus for testing water by measurement of its electrical conductivity
  Analyst, 1912,37, 538-543
• 2. An amorphous lanthanum–iridium solid solution with an open structure for efficient water splitting?
  Wei Sun,Chenglong Ma,Xinlong Tian,Jianjun Liao,Ji Yang,Chengjun Ge,Weiwei Huang J. Mater. Chem. A, 2020,8, 12518-12525
• 3. An integrated digital microfluidic chip for multiplexed proteomic sample preparation and analysis by MALDI-MS?
  Hyejin Moon,Aaron R. Wheeler,Robin L. Garrell,Chang-Jin “CJ” Kim Lab Chip, 2006,6, 1213-1219
• 4. An all-solid-state asymmetric device based on a polyaniline hydrogel for a high energy flexible supercapacitor?
  Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
• 5. An automatic determination of thoria in thoria-urania mixtures
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Biphenyls and derivatives Chlorinated biphenyls

Comprehensive Overview of 5-(3-Ethoxyphenyl)-3-chlorophenol (CAS No. 1261891-95-5): Properties, Applications, and Industry Insights

5-(3-Ethoxyphenyl)-3-chlorophenol (CAS 1261891-95-5) is a specialized organic compound gaining attention in pharmaceutical and agrochemical research due to its unique structural features. This halogenated phenol derivative combines an ethoxyphenyl moiety with a chlorophenol group, offering versatile reactivity. Recent studies highlight its potential as a building block for drug discovery, particularly in developing antimicrobial agents and enzyme inhibitors. The compound's molecular weight of 248.69 g/mol and lipophilic properties make it valuable for optimizing bioavailability in medicinal chemistry applications.

With growing interest in sustainable chemistry, researchers are exploring green synthesis methods for 5-(3-Ethoxyphenyl)-3-chlorophenol. Its structure-activity relationship (SAR) is being investigated for pesticide formulations, where modified phenols show promise as eco-friendly alternatives to traditional agrochemicals. The compound's CAS registry number 1261891-95-5 serves as a crucial identifier in patent literature and regulatory documentation, reflecting its commercial significance. Analytical techniques like HPLC purification and NMR characterization are essential for quality control during production.

The pharmacophore model of 5-(3-Ethoxyphenyl)-3-chlorophenol suggests potential interactions with biological targets, sparking interest in computational chemistry circles. Molecular docking studies indicate possible affinity for protein binding sites, aligning with current drug design trends focusing on targeted therapies. In material science, its aromatic chlorination pattern enables applications in polymer stabilization and specialty coatings, meeting demand for high-performance materials in electronics and aerospace sectors.

Industrial scale-up of CAS 1261891-95-5 requires optimization of reaction yield and purification protocols. Process chemists emphasize atom economy improvements and waste reduction strategies, responding to green chemistry principles. The compound's thermal stability and solubility profile make it suitable for various formulation technologies, including nanoparticle delivery systems gaining traction in precision agriculture applications.

Emerging research explores structure modification of 5-(3-Ethoxyphenyl)-3-chlorophenol to enhance bioactivity while reducing environmental persistence. Its metabolic pathways and degradation products are subjects of environmental fate studies, addressing concerns about chemical sustainability. The compound's logP value and hydrogen bonding capacity are frequently discussed in QSAR modeling forums, demonstrating its relevance to modern predictive toxicology approaches.

Quality standards for 1261891-95-5 require rigorous impurity profiling using LC-MS techniques, particularly for pharmaceutical intermediates. The ethoxy substitution pattern influences the compound's electronic distribution, a feature exploited in catalysis research and materials engineering. Recent patent filings indicate expanding applications in electronic materials and organic semiconductors, capitalizing on its conjugated system properties.

Supply chain considerations for 5-(3-Ethoxyphenyl)-3-chlorophenol emphasize GMP compliance and batch-to-batch consistency, especially for clinical trial materials. The compound's crystallinity and polymorphism characteristics are critical for formulation scientists developing solid dosage forms. Analytical method development focuses on stability-indicating assays to support product shelf-life determinations, reflecting industry's focus on quality by design principles.

Future directions for CAS 1261891-95-5 research include exploring its structure-property relationships for advanced material applications and investigating synergistic effects in combination therapies. The compound serves as a valuable chemical probe for studying molecular recognition phenomena, contributing to fundamental chemical biology research while maintaining compliance with regulatory guidelines for specialized chemicals.

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