Cas no 1261677-85-3 (Benzamide, 3-bromo-2-(bromomethyl)-)
Benzamide, 3-bromo-2-(bromomethyl)- Chemical and Physical Properties
Names and Identifiers
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- 3-bromo-2-(bromomethyl)Benzamide
- CID 129959417
- Benzamide, 3-bromo-2-(bromomethyl)-
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- Inchi: 1S/C8H7Br2NO/c9-4-6-5(8(11)12)2-1-3-7(6)10/h1-3H,4H2,(H2,11,12)
- InChI Key: FEHSWKIXYTXEJI-UHFFFAOYSA-N
- SMILES: BrC1=CC=CC(C(N)=O)=C1CBr
Computed Properties
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 12
- Rotatable Bond Count: 2
- Complexity: 174
- Topological Polar Surface Area: 43.1
Experimental Properties
- Density: 1.904±0.06 g/cm3(Predicted)
- Boiling Point: 340.8±37.0 °C(Predicted)
- pka: 15.10±0.50(Predicted)
Benzamide, 3-bromo-2-(bromomethyl)- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A015001664-250mg |
3-Bromo-2-(bromomethyl)benzamide |
1261677-85-3 | 97% | 250mg |
$480.00 | 2023-09-03 | |
| Alichem | A015001664-500mg |
3-Bromo-2-(bromomethyl)benzamide |
1261677-85-3 | 97% | 500mg |
$863.90 | 2023-09-03 | |
| Alichem | A015001664-1g |
3-Bromo-2-(bromomethyl)benzamide |
1261677-85-3 | 97% | 1g |
$1460.20 | 2023-09-03 |
Benzamide, 3-bromo-2-(bromomethyl)- Related Literature
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Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
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Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
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Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
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Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
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Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
Additional information on Benzamide, 3-bromo-2-(bromomethyl)-
Comprehensive Overview of Benzamide, 3-bromo-2-(bromomethyl)- (CAS No. 1261677-85-3): Properties, Applications, and Industry Insights
Benzamide, 3-bromo-2-(bromomethyl)- (CAS No. 1261677-85-3) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research due to its unique structural features. This brominated derivative of benzamide exhibits distinct reactivity patterns, making it a valuable intermediate in synthetic chemistry. With the rising demand for halogenated compounds in drug discovery, 3-bromo-2-(bromomethyl)benzamide has emerged as a key building block for designing bioactive molecules targeting various therapeutic areas.
The molecular structure of Benzamide, 3-bromo-2-(bromomethyl)- incorporates two strategically positioned bromine atoms, which enhance its utility in cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig animations. Recent studies highlight its role in developing kinase inhibitors and antimicrobial agents, aligning with current industry trends toward precision medicine. Researchers are particularly interested in its potential to modify drug solubility and metabolic stability—two critical parameters in modern pharmaceutical formulation.
From an environmental perspective, the synthesis and handling of CAS 1261677-85-3 adhere to stringent green chemistry principles, addressing growing concerns about sustainable manufacturing. Innovations in catalytic bromination methods have reduced waste generation during its production, responding to the chemical industry's sustainability goals. These advancements resonate with the increasing search queries for "eco-friendly synthetic routes" and "halogenation process optimization" across scientific databases.
Analytical characterization of 3-bromo-2-(bromomethyl)benzamide typically involves advanced techniques like HPLC-MS and NMR spectroscopy, topics frequently searched by quality control professionals. The compound's crystalline properties and stability under various pH conditions make it suitable for formulation development, particularly in solid-dosage forms. This aligns with pharmaceutical developers' searches for "excipient compatibility studies" and "API degradation analysis."
In material science, derivatives of Benzamide, 3-bromo-2-(bromomethyl)- have shown promise in creating photoactive materials for organic electronics—a hot topic in renewable energy research. Its ability to participate in polymer functionalization reactions answers frequent queries about "conductive polymer modifiers" and "OLED precursor synthesis." These applications position CAS No. 1261677-85-3 at the intersection of multiple cutting-edge technologies.
Regulatory compliance remains a critical consideration for users of this compound. While not classified as hazardous under standard protocols, proper laboratory safety measures must be observed—a subject of recurring searches like "handling brominated compounds safely." Documentation for CAS 1261677-85-3 typically includes detailed spectral data and certificates of analysis, which are essential for regulatory submissions and frequently requested by procurement specialists.
The commercial availability of Benzamide, 3-bromo-2-(bromomethyl)- through specialty chemical suppliers has expanded significantly, reflecting its growing industrial adoption. Current market analyses indicate rising interest in "custom bromination services" and "small-scale API intermediates," with this compound serving as a representative example. Its shelf-life stability and compatibility with common organic solvents further enhance its practicality for diverse research applications.
Future research directions for CAS No. 1261677-85-3 may explore its utility in bioconjugation chemistry or as a precursor for PET radiotracers—areas generating substantial academic interest. As synthetic methodologies evolve, this compound's role in facilitating C-H functionalization reactions could answer emerging search trends about "direct arylation techniques" in medicinal chemistry. These potential applications underscore the compound's enduring relevance in scientific innovation.
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