• 1. Emerging investigator series: first-principles and thermodynamics comparison of compositionally-tuned delafossites: cation release from the (001) surface of complex metal oxides?
  Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651
• 2. Evidence of rutile-to-anatase photo-induced electron transfer in mixed-phase TiO2 by solid-state NMR spectroscopy?
  Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
• 3. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 4. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 5. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789

Introduction to 2,3,5,2',3'-Pentafluorobiphenyl (CAS No: 1261465-68-2)

2,3,5,2',3'-Pentafluorobiphenyl, identified by the Chemical Abstracts Service Number (CAS No) 1261465-68-2, is a fluorinated biphenyl derivative that has garnered significant attention in the field of chemical and pharmaceutical research. This compound belongs to a class of molecules known for their unique electronic and steric properties, making them valuable in various applications ranging from materials science to drug development.

The structure of 2,3,5,2',3'-Pentafluorobiphenyl features a biphenyl core with five fluorine atoms strategically positioned at specific positions (2, 3, 5, 2', and 3'). This arrangement imparts distinct chemical characteristics that distinguish it from other biphenyl derivatives. The presence of fluorine atoms not only influences the compound's solubility and reactivity but also enhances its stability and metabolic resistance, which are critical factors in pharmaceutical applications.

In recent years, 2,3,5,2',3'-Pentafluorobiphenyl has been extensively studied for its potential in the development of novel materials and pharmaceuticals. Its electron-withdrawing nature due to fluorine substitution makes it an attractive candidate for organic electronic devices, such as organic light-emitting diodes (OLEDs) and field-effect transistors (OFETs). The compound's ability to form stable radicals and its high thermal stability further contribute to its utility in advanced material synthesis.

From a pharmaceutical perspective, 2,3,5,2',3'-Pentafluorobiphenyl has been explored as a building block for designing bioactive molecules. The fluorine atoms can modulate the pharmacokinetic properties of drug candidates by affecting lipophilicity, metabolic stability, and binding affinity to biological targets. Several research groups have reported the synthesis of fluorinated biphenyl derivatives as potential inhibitors of enzymes involved in cancer metabolism and inflammation pathways.

One notable area of research involves the use of 2,3,5,2',3'-Pentafluorobiphenyl in the development of antiviral agents. The unique electronic properties of this compound allow it to interact with viral proteases and polymerases in a manner that disrupts viral replication. Preliminary studies have shown promising results in inhibiting the replication of certain RNA viruses by incorporating 2,3,5,2',3'-Pentafluorobiphenyl into small molecule inhibitors.

The synthesis of 2,3,5,2',3'-Pentafluorobiphenyl typically involves multi-step organic reactions that require precise control over reaction conditions. Advanced synthetic techniques such as palladium-catalyzed cross-coupling reactions and fluorination methods are commonly employed to achieve high yields and purity. The growing demand for this compound has led to the development of more efficient synthetic routes that minimize waste and improve scalability.

In conclusion, 2 , 3 , 5 , 2' , 3' - Pentafluorobiphenyl ( CAS No: 1261465-68-2 ) is a versatile and highly functionalized compound with broad applications in both materials science and pharmaceuticals . Its unique structural features and chemical properties make it an invaluable asset for researchers seeking innovative solutions in drug discovery and advanced material engineering.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)