Cas no 1260772-91-5 (2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride)

2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride is a heterocyclic compound featuring a fused pyrimidine and tetrahydropyridine core with a phenyl substituent. Its hydrochloride salt form enhances solubility and stability, making it suitable for pharmaceutical and chemical research applications. The compound’s rigid bicyclic structure and aromatic phenyl group contribute to its potential as a scaffold in medicinal chemistry, particularly for targeting kinase inhibitors or CNS-active agents. Its well-defined synthetic pathway allows for high purity and reproducibility, ensuring reliability in experimental studies. The hydrochloride salt also facilitates handling and storage, making it a practical choice for further derivatization or biological evaluation.
2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride structure
1260772-91-5 structure
Product Name:2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride
CAS No:1260772-91-5
MF:C13H14ClN3
MW:247.723361492157
CID:1029661
PubChem ID:71627131
Update Time:2025-06-15

2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride
    • 2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidinehydrochloride
    • 1260772-91-5
    • DB-154770
    • 2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine HCl
    • 2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine--hydrogen chloride (1/1)
    • DTXSID80856507
    • 5,6,7,8-Tetrahydro-2-phenylpyrido[3,4-d]pyrimidine hydrochloride
    • 2-phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine;hydrochloride
    • MDL: MFCD06739078
    • Inchi: 1S/C13H13N3.ClH/c1-2-4-10(5-3-1)13-15-8-11-6-7-14-9-12(11)16-13;/h1-5,8,14H,6-7,9H2;1H
    • InChI Key: ZIQHOVHGPXCMNZ-UHFFFAOYSA-N
    • SMILES: Cl.N1CC2C(=CN=C(C3C=CC=CC=3)N=2)CC1

Computed Properties

  • Exact Mass: 247.0876252g/mol
  • Monoisotopic Mass: 247.0876252g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 1
  • Complexity: 225
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 37.8?2

2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A029181451-1g
2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride
1260772-91-5 95%
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$646.84 2023-09-03
Chemenu
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Additional information on 2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride

Comprehensive Overview of 2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride (CAS No. 1260772-91-5)

2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride (CAS No. 1260772-91-5) is a heterocyclic compound that has garnered significant attention in pharmaceutical and biochemical research due to its unique structural properties and potential therapeutic applications. This compound belongs to the pyridopyrimidine family, a class of nitrogen-containing bicyclic structures known for their versatility in drug discovery. The presence of a phenyl group and a tetrahydropyrido ring system enhances its binding affinity to various biological targets, making it a promising candidate for further investigation.

In recent years, the demand for small molecule inhibitors and kinase modulators has surged, driven by advancements in precision medicine and targeted therapies. Researchers are particularly interested in 2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride due to its potential role in modulating enzymatic activity and signaling pathways. Its hydrochloride salt form improves solubility and bioavailability, which are critical factors in drug formulation and delivery. This compound is often explored in the context of cancer research, neurodegenerative diseases, and metabolic disorders, aligning with current trends in biomedical science.

The synthesis of 2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride involves multi-step organic reactions, including cyclization and functional group transformations. Its CAS No. 1260772-91-5 serves as a unique identifier in chemical databases, facilitating efficient literature searches and regulatory compliance. Analytical techniques such as NMR spectroscopy, mass spectrometry, and HPLC are employed to characterize its purity and structural integrity, ensuring reproducibility in research settings.

From an industrial perspective, this compound is valued for its scalability and compatibility with high-throughput screening platforms. Pharmaceutical companies and academic institutions are actively investigating its derivatives to optimize pharmacokinetic profiles and minimize off-target effects. The growing interest in personalized medicine and AI-driven drug design has further amplified the relevance of such compounds, as they offer a robust framework for structure-activity relationship (SAR) studies.

In addition to its therapeutic potential, 2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride is also studied for its material science applications. Its aromatic and heterocyclic components contribute to unique electronic properties, making it a candidate for organic semiconductors and catalysis. This interdisciplinary appeal underscores its importance in both life sciences and engineering domains.

As the scientific community continues to explore novel chemical entities, CAS No. 1260772-91-5 remains a focal point for innovation. Its integration into combinatorial chemistry libraries and virtual screening pipelines highlights its adaptability to modern research methodologies. For researchers seeking reliable suppliers, it is essential to verify certificates of analysis (CoA) and good manufacturing practices (GMP) compliance to ensure quality and consistency.

In summary, 2-Phenyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride represents a versatile and highly studied compound with broad applications in drug development and material science. Its pyridopyrimidine core and hydrochloride salt form contribute to its scientific and industrial relevance, making it a valuable asset in contemporary research. Future studies will likely uncover additional functionalities, further solidifying its role in advancing human health and technology.

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