Cas no 1260666-18-9 ({1H-pyrazolo4,3-bpyridin-5-yl}methanamine)
{1H-Pyrazolo[4,3-b]pyridin-5-yl}methanamine is a heterocyclic amine derivative featuring a fused pyrazolopyridine core, which serves as a versatile scaffold in medicinal chemistry and drug discovery. Its rigid bicyclic structure enhances binding affinity and selectivity, making it valuable for targeting biologically relevant receptors or enzymes. The primary amine functionality at the 5-position allows for further derivatization, enabling the synthesis of diverse pharmacophores. This compound exhibits potential applications in the development of kinase inhibitors, antiviral agents, or CNS-targeted therapeutics due to its favorable physicochemical properties and metabolic stability. Its synthetic accessibility and modularity further contribute to its utility as an intermediate in organic and pharmaceutical research.
1260666-18-9 structure
Product Name:{1H-pyrazolo4,3-bpyridin-5-yl}methanamine
CAS No:1260666-18-9
MF:C7H8N4
MW:148.16522026062
CID:4828406
PubChem ID:72213570
Update Time:2025-05-28
{1H-pyrazolo4,3-bpyridin-5-yl}methanamine Chemical and Physical Properties
Names and Identifiers
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- (1H-Pyrazolo[4,3-b]pyridin-5-yl)methanamine
- 1h-pyrazolo[4,3-b]pyridine-5-methanamine
- AB73720
- 1H-PYRAZOLO[4,3-B]PYRIDIN-5-YLMETHYLAMINE
- {1H-pyrazolo4,3-bpyridin-5-yl}methanamine
-
- Inchi: 1S/C7H8N4/c8-3-5-1-2-6-7(10-5)4-9-11-6/h1-2,4H,3,8H2,(H,9,11)
- InChI Key: KYOGGCCICUHQBH-UHFFFAOYSA-N
- SMILES: N1C(CN)=CC=C2C=1C=NN2
Computed Properties
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 138
- XLogP3: -0.5
- Topological Polar Surface Area: 67.6
{1H-pyrazolo4,3-bpyridin-5-yl}methanamine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029181935-1g |
(1H-Pyrazolo[4,3-b]pyridin-5-yl)methanamine |
1260666-18-9 | 95% | 1g |
$1681.00 | 2023-09-03 | |
| Alichem | A029181935-5g |
(1H-Pyrazolo[4,3-b]pyridin-5-yl)methanamine |
1260666-18-9 | 95% | 5g |
3,484.00 USD | 2021-06-01 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1846638-1g |
(1h-Pyrazolo[4,3-b]pyridin-5-yl)methanamine |
1260666-18-9 | 98% | 1g |
¥10920.00 | 2024-08-09 | |
| Enamine | EN300-1652942-0.05g |
{1H-pyrazolo[4,3-b]pyridin-5-yl}methanamine |
1260666-18-9 | 0.05g |
$1140.0 | 2023-06-04 | ||
| Enamine | EN300-1652942-0.1g |
{1H-pyrazolo[4,3-b]pyridin-5-yl}methanamine |
1260666-18-9 | 0.1g |
$1195.0 | 2023-06-04 | ||
| Enamine | EN300-1652942-0.25g |
{1H-pyrazolo[4,3-b]pyridin-5-yl}methanamine |
1260666-18-9 | 0.25g |
$1249.0 | 2023-06-04 | ||
| Enamine | EN300-1652942-0.5g |
{1H-pyrazolo[4,3-b]pyridin-5-yl}methanamine |
1260666-18-9 | 0.5g |
$1302.0 | 2023-06-04 | ||
| Enamine | EN300-1652942-1.0g |
{1H-pyrazolo[4,3-b]pyridin-5-yl}methanamine |
1260666-18-9 | 1g |
$1357.0 | 2023-06-04 | ||
| Enamine | EN300-1652942-2.5g |
{1H-pyrazolo[4,3-b]pyridin-5-yl}methanamine |
1260666-18-9 | 2.5g |
$2660.0 | 2023-06-04 | ||
| Enamine | EN300-1652942-5.0g |
{1H-pyrazolo[4,3-b]pyridin-5-yl}methanamine |
1260666-18-9 | 5g |
$3935.0 | 2023-06-04 |
{1H-pyrazolo4,3-bpyridin-5-yl}methanamine Related Literature
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Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
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Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
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Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
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Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
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