Cas no 1260374-05-7 ((4-(Methoxymethoxy)-2-methylphenyl)boronic acid)
(4-(Methoxymethoxy)-2-methylphenyl)boronic acid is a versatile boronic acid derivative widely used in Suzuki-Miyaura cross-coupling reactions, a key method for forming carbon-carbon bonds in organic synthesis. The compound features a methoxymethoxy-protected hydroxyl group at the para position and a methyl substituent at the ortho position relative to the boronic acid functionality, enhancing its stability and reactivity. This structural modification improves solubility in common organic solvents and reduces protodeboronation, a common side reaction in boronic acid chemistry. Its electron-rich aromatic system facilitates efficient transmetalation in palladium-catalyzed coupling reactions, making it valuable for constructing complex biaryl structures in pharmaceuticals, agrochemicals, and materials science. The protecting group can be selectively removed under mild acidic conditions, offering additional synthetic flexibility.
1260374-05-7 structure
Product Name:(4-(Methoxymethoxy)-2-methylphenyl)boronic acid
CAS No:1260374-05-7
MF:C9H13BO4
MW:196.008123159409
MDL:MFCD11111901
CID:1026321
Update Time:2025-07-02
(4-(Methoxymethoxy)-2-methylphenyl)boronic acid Chemical and Physical Properties
Names and Identifiers
-
- (4-(Methoxymethoxy)-2-methylphenyl)boronic acid
- [4-(Methoxymethoxy)-2-methylphenyl]boronic acid
-
- MDL: MFCD11111901
- Inchi: 1S/C9H13BO4/c1-7-5-8(14-6-13-2)3-4-9(7)10(11)12/h3-5,11-12H,6H2,1-2H3
- InChI Key: CLCGIQQHHJUZFU-UHFFFAOYSA-N
- SMILES: O(COC)C1C=CC(B(O)O)=C(C)C=1
Computed Properties
- Exact Mass: 196.09100
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 14
- Rotatable Bond Count: 4
Experimental Properties
- PSA: 58.92000
- LogP: -0.34250
(4-(Methoxymethoxy)-2-methylphenyl)boronic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Matrix Scientific | 203619-5g |
[4-(Methoxymethoxy)-2-methylphenyl]boronic acid |
1260374-05-7 | 5g |
$543.00 | 2023-09-05 | ||
| Matrix Scientific | 203619-10g |
[4-(Methoxymethoxy)-2-methylphenyl]boronic acid |
1260374-05-7 | 10g |
$905.00 | 2023-09-05 | ||
| TRC | M331703-50mg |
(4-(Methoxymethoxy)-2-methylphenyl)boronic Acid |
1260374-05-7 | 50mg |
$ 50.00 | 2022-06-02 | ||
| TRC | M331703-100mg |
(4-(Methoxymethoxy)-2-methylphenyl)boronic Acid |
1260374-05-7 | 100mg |
$ 65.00 | 2022-06-02 | ||
| TRC | M331703-500mg |
(4-(Methoxymethoxy)-2-methylphenyl)boronic Acid |
1260374-05-7 | 500mg |
$ 95.00 | 2022-06-02 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | M50370-1g |
(4-(Methoxymethoxy)-2-methylphenyl)boronic acid |
1260374-05-7 | 1g |
¥678.0 | 2021-09-08 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | M50370-250mg |
(4-(Methoxymethoxy)-2-methylphenyl)boronic acid |
1260374-05-7 | 250mg |
¥228.0 | 2021-09-08 | ||
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | M190361-250mg |
(4-(Methoxymethoxy)-2-methylphenyl)boronic acid |
1260374-05-7 | 96% | 250mg |
¥174.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | M190361-1g |
(4-(Methoxymethoxy)-2-methylphenyl)boronic acid |
1260374-05-7 | 96% | 1g |
¥514.90 | 2023-09-01 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | M842402-250mg |
(4-(Methoxymethoxy)-2-methylphenyl)boronic acid |
1260374-05-7 | 96% | 250mg |
¥226.00 | 2022-09-01 |
(4-(Methoxymethoxy)-2-methylphenyl)boronic acid Related Literature
-
Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
-
Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
-
Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
-
Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
-
Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
1260374-05-7 ((4-(Methoxymethoxy)-2-methylphenyl)boronic acid) Related Products
- 361543-99-9((4-methoxy-2,6-dimethylphenyl)boronic acid)
- 617689-07-3((5-Methoxy-2-methylphenyl)boronic acid)
- 355836-08-7(2,4-Dimethyl-6-methoxyphenylboronic acid)
- 313545-31-2((4-Ethoxy-2-methylphenyl)boronic acid)
- 208399-66-0((4-methoxy-2-methylphenyl)boronic acid)
- 341006-18-6(5-(Methoxymethoxy)-2-methylphenylboronic Acid)
- 1315342-15-4((4-Ethoxy-2,6-dimethylphenyl)boronic acid)
- 1256345-61-5((5-Cyano-2-(methoxymethoxy)phenyl)boronic acid)
- 94838-88-7((2-formyl-4,5-methylenedioxy)benzeneboronicacid)
- 478685-71-1(2-(Methoxymethoxy)-5-methylphenylboronic Acid)
Recommended suppliers
鉅瀾化工科技(青島)有限公司
Gold Member
CN Supplier
Bulk
Xiamen PinR Bio-tech Co., Ltd.
Gold Member
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
CN Supplier
Bulk
Hebei Liye chemical Co.,Ltd
Gold Member
CN Supplier
Bulk
Wuhan ChemNorm Biotech Co.,Ltd.
Gold Member
CN Supplier
Reagent