• 1. Evidence of pre-micellar aggregates in aqueous solution of amphiphilic PDMS–PEO block copolymer?
  Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
• 2. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 3. Distribution pattern and allocation of defects in hydrogenated ZnO thin films?
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• 5. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzyl alcohols

Comprehensive Overview of (5-Iodo-2-methylphenyl)methanol (CAS No. 1260242-01-0): Properties, Applications, and Industry Insights

(5-Iodo-2-methylphenyl)methanol (CAS No. 1260242-01-0) is a specialized organic compound widely recognized for its versatile applications in pharmaceutical intermediates, material science, and fine chemical synthesis. With the increasing demand for halogenated aromatic derivatives in drug discovery and advanced materials, this compound has garnered significant attention from researchers and industry professionals alike. The presence of both iodo and hydroxymethyl functional groups on the aromatic ring makes it a valuable building block for further chemical modifications.

The compound’s molecular structure, featuring a 5-iodo-2-methylphenyl core, enables selective reactivity in cross-coupling reactions, such as Suzuki-Miyaura or Sonogashira couplings, which are pivotal in modern organic synthesis. Recent studies highlight its utility in designing fluorescence probes and bioactive molecules, aligning with trends in precision medicine and molecular imaging. Researchers frequently search for "iodo-substituted benzyl alcohols" or "CAS 1260242-01-0 applications," reflecting its growing relevance in interdisciplinary fields.

From a physicochemical perspective, (5-Iodo-2-methylphenyl)methanol exhibits moderate solubility in polar organic solvents like ethanol and dimethyl sulfoxide (DMSO), while remaining stable under standard laboratory conditions. Its melting point and spectral data (e.g., NMR, IR) are critical for quality control, a topic often queried in academic forums. The compound’s synthetic routes—often involving iodination of 2-methylbenzyl alcohol derivatives—are optimized for high yield and purity, addressing industrial demands for scalable processes.

In the context of green chemistry, innovations in catalytic iodination and solvent-free reactions have positioned 1260242-01-0 as a case study for sustainable halogenation methods. Environmental concerns and regulatory shifts toward eco-friendly synthesis drive searches for "halogenated compound alternatives" or "iodo-arene safety protocols," underscoring the need for balanced efficiency and sustainability.

Market analyses indicate rising procurement of (5-Iodo-2-methylphenyl)methanol by contract research organizations (CROs) and API manufacturers, particularly in regions with robust pharmaceutical R&D infrastructure. Its role in developing PET radiotracers (due to iodine’s isotopic properties) further elevates its profile in diagnostic imaging—a hotspot in medical research. FAQs like "how to store iodinated aromatics" or "1260242-01-0 supplier specifications" reflect practical industry concerns.

Future prospects for CAS No. 1260242-01-0 include explorations in covalent organic frameworks (COFs) and photocatalysis, where its structural motifs could enhance material properties. As AI-driven drug discovery accelerates, computational studies on iodo-arene reactivity are likely to expand, making this compound a recurring subject in cheminformatics databases. Collaborative efforts between academia and industry will continue to unlock its potential, ensuring its prominence in next-generation chemical innovations.

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