Cas no 126-07-8 (Griseofulvin)

Griseofulvin is an antifungal antibiotic derived from Penicillium griseofulvum, primarily used to treat dermatophytic infections of the skin, hair, and nails. It functions by inhibiting fungal cell mitosis through binding to microtubules, disrupting spindle formation and hyphal growth. Griseofulvin is particularly effective against Trichophyton, Microsporum, and Epidermophyton species. Its lipophilic nature allows for accumulation in keratinized tissues, ensuring prolonged antifungal activity. The compound is available in oral formulations, with absorption enhanced by fatty meals. Key advantages include its targeted action against dermatophytes, established clinical efficacy, and a well-characterized safety profile. It remains a first-line treatment for tinea infections where systemic therapy is required.
Griseofulvin structure
Griseofulvin structure
Product Name:Griseofulvin
CAS No:126-07-8
MF:C17H17CLO6
MW:352.77
MDL:MFCD00082343
CID:36154
PubChem ID:135727206
Update Time:2025-09-16

Griseofulvin Chemical and Physical Properties

Names and Identifiers

    • Griseofulvin
    • (+)-GRISEOFULVIN
    • [2S-TRANS]-7-CHLORO-2,4,6-TRIMETHOXY-6'-METHYLSPIRO[BENZOFURAN-2(3H), 1'(2)-CYCLOHEXANE]-3,4'-DIONE
    • (2S)-TRANS-7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO(BENZOFURAN-2[3H],1'-[2]CYCLOHEXENE)-3,4'-DIONE
    • 7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYL-, (1'S-TRANS)-SPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE
    • (+)-griseofulvi
    • (2s-trans)-7-chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3h),1'-[2]cy
    • (2s-trans)-xy-6'-methyl
    • GRISEOFULVIN(RG)
    • Griseofulvine
    • (1’S,6’R)-7-chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3H),1’-[2]cyclohexene]-3,4’-dione
    • (1’S-trans)- 7-chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3H),1’-cyclohex-2’-ene]-3,4’-dione
    • (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
    • 7-chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1’-(2’-methoxy-6’-methylcyclohex-2’-en-4’-one)
    • Amudane
    • Curling factor
    • Fulcin
    • Fulvicin
    • Grifulvin
    • Grifulvin V
    • Grisact
    • Griseofulvin Permeability Diameter
    • Gris-PEG
    • (2S)-trans-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro(benzofuran-2[3H],1′-[2]cyclohexene)-3,4′-dione
    • Gricin
    • Griseo
    • Grysio
    • Poncyl
    • Fulcine
    • Fulvina
    • Greosin
    • Lamoryl
    • Amudane, Fulvicin, Grisactin
    • NCGC00091120-02
    • BDBM31775
    • Fungivin
    • GRISEOFULVIN, ULTRAMICROSIZE
    • GRISEOFULVINUM [WHO-IP LATIN]
    • Tox21_303005
    • (2S-TRANS)-7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO
    • DDUHZTYCFQRHIY-RBHXEPJQSA-N
    • SR-05000001535-4
    • IDI1_000154
    • Griseofulviin (microsize)
    • Grisactin V
    • BPBio1_000299
    • 7-Chloro-2',4,6-trimethoxy-6'beta-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione
    • Epigriseofulvin
    • (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
    • DivK1c_006432
    • D00209
    • GRISEOFULVIN (USP-RS)
    • CS-3426
    • KBio2_001296
    • BRD-K08273968-001-19-0
    • SR-01000837512
    • SR-01000837512-2
    • SPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE, 7 -CHLORO-2',4,6-TRIMETHOXY-6'-BETA-METHYL-
    • DB00400
    • Likuden
    • EINECS 204-767-4
    • MFCD00082343
    • Prestwick_247
    • NS00011725
    • SR-05000001535-1
    • Biogrisin-FP
    • BSPBio_001621
    • NCGC00256353-01
    • NSC 34533
    • Griseofulvin (microsize)
    • Fulvicin Bolus
    • DTXCID20674
    • CS-0695022
    • NCGC00091120-01
    • GRISEOFULVIN (MART.)
    • FULVICIN P/G 330
    • SCHEMBL21988
    • AS-13736
    • GRISEOFULVIN PERMEABILITY DIAMETER (USP-RS)
    • CHEMBL562
    • Neo-Fulcin
    • Spectrum2_000213
    • 7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1',- [2]cyclohexene]-3,4'-dione
    • LMPK13060001
    • ACon1_001843
    • AB00052005_07
    • Griseofulvin, Pharmaceutical Secondary Standard; Certified Reference Material
    • Grisofulvin
    • Griseofulvin, British Pharmacopoeia (BP) Reference Standard
    • Griseofulvinum
    • HMS2091A03
    • NCGC00091120-08
    • NCGC00091120-09
    • HMS1923E09
    • D01AA08
    • GRISEOFULVIN [INN]
    • D01BA01
    • Griseofulvine [INN-French]
    • 107912-37-8
    • Grisetin
    • 7-CHLORO-4,6-DIMETHOXYCOUMARAN-3-ONE-2-SPIRO-1'-(2'-MET HOXY-6'-METHYLCYCLOHEX-2'-EN-4'-ONE)
    • Griseofulvina
    • Griseofulvinum [INN-Latin]
    • Grisefuline
    • Griseofulvina [INN-Spanish]
    • BRN 0095226
    • MLS002152905
    • NSC-755822
    • (2S,6'R)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzo(b)furan-2(3H),1'-(cyclohex-2'-ene))-3,4'-dione
    • GRISEOFULVIN [EP MONOGRAPH]
    • BT164513
    • GRISEOFULVIN, ULTRAMICROCRYSTALLINE
    • MLS001304062
    • Griseofulvin (JAN/USP/INN)
    • GRISEOFULVIN [WHO-IP]
    • NCGC00091120-07
    • UNII-32HRV3E3D5
    • USAF SC-2
    • 7-CHLORO-4,6-DIMETHOXYCOUMARAN-3-ONE-2-SPIRO-1'-(2'-METHOXY)-6'-METHYLCYCLO-HEX-2'-EN-4'-ONE
    • HSDB 1722
    • AKOS015896380
    • Z756424454
    • Grisovin FP
    • ACon0_000953
    • NCGC00259784-01
    • GRISEOFULVIN PERMEABILITY DIAMETER [USP-RS]
    • Tox21_202235
    • CCRIS 320
    • SDCCGMLS-0066450.P001
    • GRISEOFULVIN, MICROCRYSTALLINE
    • 7-Chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1'-(2'-methoxy-6'-methylcyclohex-2'-en-4'-one)
    • Griseofulvin and Alpha-IFN
    • Griseofulvin, VETRANAL(TM), analytical standard
    • BRD-K08273968-001-09-1
    • Fulvistatin
    • 7-Chloro-4,6,2'-trimethoxy-6'-methylgris-2'-en-3,4'-dione
    • GRISEOFULVIN [USP MONOGRAPH]
    • Gris-peg (TN)
    • SMR000718755
    • Griseofulvin-forte
    • GRISEOFULVIN [WHO-DD]
    • GRISEOFULVIN [IARC]
    • FULVICIN P/G 165
    • Ultramicrosize Griseofulvin Tablets
    • NSC755822
    • NCGC00091120-03
    • Ultramicrosize Griseofulvin
    • GRE
    • Griseofulvin Permeability Diameter, United States Pharmacopeia (USP) Reference Standard
    • KBio2_006432
    • Griseofulvin, from Penicillium griseofulvum, 97.0-102.0%
    • (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methyl-spiro[benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
    • Griseofulvine (INN-French)
    • Fulvicin U/F Powder
    • Fulvicin U/F Tablets
    • GRISEOFULVIN [HSDB]
    • NCGC00091120-06
    • SR-05000001535-3
    • CCG-38416
    • (1'S,6'R)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione
    • NINDS_000154
    • Griscofulvin
    • Griseofulvin Oral Suspension
    • Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S-trans)-
    • KBioGR_001454
    • BIM-0051396.0001
    • (1'S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
    • Griseofulvin (Standard)
    • CHEBI:27779
    • Griseofulvina (INN-Spanish)
    • Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S,6'R)-
    • NCGC00091120-04
    • Fulvicin U/F Bolus Veterinary
    • C06686
    • (2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione
    • IDIFULVIN
    • Gresfeed
    • Griseofulvin,(S)
    • GRISEOFULVIN (EP MONOGRAPH)
    • Grisactin V (TN)
    • BRD-K08273968-001-05-9
    • SpecPlus_000336
    • 7-CHLORO-2',4,6-TRIMETHOXY-6'-BETA-SPIRO(BENZOFURAN-2(3H), 1'-(2)CYCLOHEXENE-3,4'-DIONE
    • Spectrum5_000648
    • (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
    • Griseofulvin,microsize
    • CPD000718755
    • GRISEOFULVIN [MART.]
    • (1'S-trans)- 7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-cyclohex-2'-ene)-3,4'-dione
    • GRISEOFULVIN [JAN]
    • NCGC00091120-13
    • SPECTRUM200046
    • NC00616
    • Fulvicin-U/F
    • Fulvicin-U/F (Veterinary)
    • HMS500H16
    • Griseomix
    • 126-07-8
    • Murfulvin
    • GRISEOFULVIN [USP-RS]
    • ULTRAGRIS-165
    • Tox21_111087_1
    • Fulvidex (Veterinary)
    • Pharmakon1600-00200046
    • GRISEOFULVIN, MICROSIZE
    • Spirofulvin
    • (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro(1-benzofuran-2,1'-cyclohex(2)ene)-3,4'-dione
    • Griseoflulvin
    • DTXSID8020674
    • Prestwick3_000226
    • Fulvidex
    • Q416096
    • Grizeofulvin
    • fulvicin UF
    • (1'S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-cyclohex-2'-ene)-3,4'-dione
    • Spectrum_000816
    • Griseofulvin, (+)-
    • HMS3712N13
    • GRISEOFULVIN [ORANGE BOOK]
    • KBio1_000154
    • s4071
    • Q-201178
    • NSC-34533
    • KBioSS_001296
    • DivK1c_000154
    • KBio1_001376
    • KBio3_001121
    • (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methylbenzofuran-2-spiro-1'-cyclohex-2'-ene-3,4'-dione
    • GRISEOFULVIN [GREEN BOOK]
    • Grisactin
    • BSPBio_000271
    • Griseofulvin forte
    • Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (2S-trans)-
    • SPBio_000225
    • Fulvicin-U/F Powder and Tablets
    • 32HRV3E3D5
    • KBio2_003864
    • EN300-52615
    • Griseofulvin, United States Pharmacopeia (USP) Reference Standard
    • GRISEOFULVIN [VANDF]
    • Grysio (Microsize)
    • GRISEOFULVIN POWDER
    • NCGC00091120-05
    • Fulvicin-P/G
    • 5-18-05-00150 (Beilstein Handbook Reference)
    • MLS002154239
    • GRISEOFULVIN (IARC)
    • GRISEOFULVIN [MI]
    • Guservin
    • Griseofulvin (USP:INN:BAN:JAN)
    • BIDD:GT0024
    • Griseofulvin, European Pharmacopoeia (EP) Reference Standard
    • Griseofulvin [USP:INN:BAN:JAN]
    • (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
    • 7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE
    • Tox21_111087
    • Griseofulvin 100 microg/mL in Acetonitrile
    • GRISEOFULVIN (USP MONOGRAPH)
    • G0384
    • Griseofulvin, Antibiotic for Culture Media Use Only
    • HMS2095N13
    • Griseofulvin (USP:INN)
    • Fulvinil
    • SPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE, 7-CHLORO-2',4,6-TRIMETHOXY-6'BETA-METHYL-
    • EPA Pesticide Chemical Code 471400
    • Griseofulvinum (INN-Latin)
    • AI3-51015
    • Grifulin
    • Fulvicin Bolus (Veterinary)
    • 7-CHLORO-2',4,6-TRIMETHOXY-6'.BETA.-METHYLSPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE
    • Delmofulvina
    • Grisactin Ultra
    • Grisovin
    • Fulvican grisactin
    • HMS2235F13
    • MEGxm0_000184
    • Caswell No. 471B
    • HMS3259D05
    • Griseofulvin microsize
    • Spectrum4_000927
    • HY-17583
    • Fulvicin P/G
    • Griseofulvin [USP:INN]
    • SR-05000001535
    • Spectrum3_000161
    • HY-17583R
    • ULTRAGRIS-330
    • Xuanjing
    • SMR000058317
    • MLS000028436
    • MLSMR
    • MLS001183742
    • MLS001148597
    • 2884-22-2
    • (+)-Epigriseofulvin; 7-Chloro-2',4,6-trimethoxy-6'alpha-methyl-spiro[benzofuran-2(3H)-1'-[2]cyclohexene]-3,4'-dione; (1'R,6'R)-7-Chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
    • GLXC-04995
    • BRD-K08273968-001-16-6
    • MDL： MFCD00082343
    • Inchi： 1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
    • InChI Key： DDUHZTYCFQRHIY-RBHXEPJQSA-N
    • SMILES： O=C1[C@]2(C(OC)=CC(C[C@H]2C)=O)OC3=C(Cl)C(OC)=CC(OC)=C13
    • BRN： 95226

Computed Properties

  • Exact Mass: 352.07100
  • Monoisotopic Mass: 352.071
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 24
  • Rotatable Bond Count: 3
  • Complexity: 575
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Functional 3D Acceptor Count: 6
  • isomeric RMSD: 0.6
  • CID conformational isomer Count: 8
  • Surface Charge: 0
  • Tautomer Count: 2
  • XLogP3: nothing
  • Functional 3D ring Count: 3
  • Rotatable Bond Count: 3.6
  • Topological Polar Surface Area: 71.1A^2

Experimental Properties

  • Color/Form: Powder
  • Density: 1.2579 (rough estimate)
  • Melting Point: 218.0 to 222.0 deg-C
  • Boiling Point: 527.9°C at 760 mmHg
  • Flash Point: 228°C
  • Refractive Index: 1.4429 (estimate)
  • Water Partition Coefficient: Almost insoluble
  • PSA: 71.06000
  • LogP: 2.81030
  • λmax: 321(CHCl3)(lit.)
  • Merck: 4549
  • Specific Rotation: 354 o (c=1, dimethylform)
  • FEMA: 2160
  • Color/Form: 2?mg/mL in acetonitrile
  • Solubility: Soluble in tetrachloroethane, acetone or chloroform, slightly soluble in methanol or ethanol, very slightly soluble in water

Griseofulvin Security Information

  • Symbol: GHS07 GHS08
  • Prompt：dangerous
  • Signal Word：Danger
  • Hazard Statement： H317,H351,H360
  • Warning Statement： P201,P280,P308+P313
  • Hazardous Material transportation number：UN 1648 3 / PGII
  • WGK Germany：3
  • Hazard Category Code： R60;R61;R40;R43
  • Safety Instruction： S53-S22-S36/37/39-S45
  • Regulatory Condition Code：Class Q (sugars, alkaloids, antibiotics, hormones)
  • RTECS：WG9800000
  • Hazardous Material Identification： T Xn
  • Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
  • Risk Phrases：R60; R61; R40; R43

Griseofulvin Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd.
G0384-25G
(+)-Griseofulvin
 126-07-8 >95.0%(HPLC)(qNMR)
25g
 ￥290.00 2024-04-17
TRC
G787500-25mg
Griseofulvin
 126-07-8
25mg
 $ 57.00 2023-09-07
TRC
G787500-100mg
Griseofulvin
 126-07-8
100mg
 $64.00 2023-05-18
TRC
G787500-5g
Griseofulvin
 126-07-8
5g
 $ 74.00 2023-09-07
TRC
G787500-25g
Griseofulvin
 126-07-8
25g
 $170.00 2023-05-18
TRC
G787500-50g
Griseofulvin
 126-07-8
50g
 $ 316.00 2023-09-07
abcr
AB131510-5 g
(+)-Griseofulvin, 97%; .
 126-07-8 97%
5 g
 €64.00 2023-07-20
abcr
AB131510-10 g
(+)-Griseofulvin, 97%; .
 126-07-8 97%
10g
 €54.50 2021-09-16
abcr
AB131510-25 g
(+)-Griseofulvin, 97%; .
 126-07-8 97%
25 g
 €122.20 2023-07-20
abcr
AB131510-100 g
(+)-Griseofulvin, 97%; .
 126-07-8 97%
100 g
 €349.00 2023-07-20

Griseofulvin Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:126-07-8)(+)-Griseofulvin
Order Number:sfd4131
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:33
Price ($):discuss personally
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:126-07-8)Griseofulvin
Order Number:LE12429;LE1486
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:07
Price ($):discuss personally
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:126-07-8)Griseofulvin
Order Number:A805480
Stock Status:in Stock
Quantity:100g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 04:43
Price ($):215.0
Zhengzhou Baoyu Pharmaceutical Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
(CAS:126-07-8)(+)-Griseofulvin
Order Number:LE036
Stock Status:in Stock
Quantity:5KG/1KG/25KG/100KG
Purity:99% HPLC
Pricing Information Last Updated:Thursday, 14 August 2025 14:44
Price ($):negotiated

Griseofulvin Spectrogram

MS-MS
MS-MS
1H NMR 300 MHz DMSO
1H NMR
13C NMR
13C NMR

Griseofulvin Related Literature

Related Categories

Additional information on Griseofulvin

Griseofulvin: A Comprehensive Guide to the Antifungal Compound (CAS No. 126-07-8)

Griseofulvin (CAS No. 126-07-8) is a naturally occurring antifungal antibiotic derived from the Penicillium griseofulvum mold. This systemic antifungal agent has been widely used in clinical practice for decades, particularly for treating dermatophytoses (fungal infections of the skin, hair, and nails). The compound's unique mechanism of action, targeting fungal microtubules, makes it distinct from other antifungal medications in the market.

In recent years, Griseofulvin has gained renewed attention due to the global rise in antimicrobial resistance and the increasing prevalence of recalcitrant fungal infections. Many patients searching for "natural antifungal treatments" or "long-term solutions for nail fungus" often encounter this medication in their research. While not technically a "natural remedy" (as it's produced through fermentation and purification processes), its fungal origin makes it an interesting bridge between conventional and alternative medicine approaches.

The pharmaceutical properties of CAS No. 126-07-8 are particularly noteworthy. As a lipophilic compound, Griseofulvin demonstrates excellent keratin affinity, allowing it to concentrate in the skin, hair, and nails - the very tissues affected by dermatophytes. This property explains why it remains a first-line treatment for tinea capitis (scalp ringworm) in children, despite the development of newer antifungals. Current research trends focus on "improving Griseofulvin bioavailability" through novel formulations, addressing one of its historical limitations.

From a biochemical perspective, Griseofulvin works by binding to fungal microtubules, disrupting mitotic spindle formation and thereby inhibiting cell division. This fungistatic mechanism differs from the fungicidal action of many modern antifungals that target ergosterol synthesis. Interestingly, this unique action has led to investigations into potential "Griseofulvin repurposing" for other medical applications, including certain proliferative disorders - a hot topic in drug rediscovery research.

Patients frequently search for "Griseofulvin vs Terbinafine" comparisons when considering treatment options. While both are effective against dermatophytes, key differences exist: Griseofulvin requires longer treatment durations (often weeks to months) but has an excellent safety profile in pediatric populations. The medication's spectrum of activity is narrower than newer azoles, making proper diagnosis crucial before prescription. These nuances are important for healthcare providers addressing "persistent fungal infections" in clinical practice.

The pharmacokinetics of CAS No. 126-07-8 reveal interesting characteristics. Absorption is significantly enhanced by fatty foods, leading to standard recommendations to take the medication with high-fat meals. This "food effect on Griseofulvin absorption" remains a key patient education point. Modern formulation scientists are exploring "nanoparticle delivery systems" to overcome this variability, with promising results in recent preclinical studies.

In the context of global health dermatology, Griseofulvin maintains importance due to its affordability and proven efficacy against common superficial mycoses. Organizations combating "neglected tropical diseases" often include it in essential medicine lists for resource-limited settings. However, the emergence of "azole-resistant dermatophytes" has sparked debate about whether older drugs like Griseofulvin might see expanded use in certain resistance scenarios.

Quality control of Griseofulvin products remains crucial, with pharmacopeial standards specifying tests for "related substances in CAS 126-07-8" and crystalline form verification. The compound exists in multiple polymorphs, affecting dissolution rates and therapeutic outcomes. This technical aspect is particularly relevant to pharmaceutical manufacturers optimizing "Griseofulvin tablet formulations" for consistent performance.

Environmental scientists have studied Griseofulvin's ecological impact, given its fungal origin and medical use. While not classified as environmentally hazardous, proper "pharmaceutical waste disposal" remains important to prevent potential effects on soil microbiota. This consideration aligns with growing public interest in "sustainable medication practices" and green pharmacy initiatives.

Looking forward, Griseofulvin (CAS No. 126-07-8) continues to evolve scientifically. Research into "combination antifungal therapies" sometimes includes this classic agent, seeking synergistic effects with newer drugs. Its historical success against dermatophytes ensures ongoing relevance in medical mycology, while novel delivery approaches may expand its clinical utility in our era of precision medicine.

126-07-8 (Griseofulvin) Related Products

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:126-07-8)(+)-Griseofulvin
sfd4131
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:126-07-8)Griseofulvin
LE12429;LE1486
Purity:99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry
Email