Cas no 125966-88-3 ((4,6-Dimethoxypyrimidin-2-yl)methanol)
(4,6-Dimethoxypyrimidin-2-yl)methanol Chemical and Physical Properties
Names and Identifiers
-
- (4,6-Dimethoxypyrimidin-2-yl)methanol
- 4,6-Dimethoxy-2-(hydroxymethyl)pyrimidine
- 4,6-dimethoxy-2-Pyrimidinemethanol
- 4,6-DIMETHOXYPYRIMIDINE-2YL-METHANOL
- 2-hydroxymethyl-4,6-dimethoxypyrimidine
- 2-pyrimidinemethanol,4,6-dimethoxy-
- AGN-PC-001O9S
- AK129487
- HP22905
- KB-26116
- PB14036
- RL01262
- SCHEMBL13738921
- MFCD22566214
- AKOS016014276
- DB-062423
- J-510321
- P13318
- A850748
- CS-0045823
- DTXSID60560953
- SY268030
- 125966-88-3
- 4,6-Dimethoxypyrimidine-2-methanol
-
- MDL： MFCD16039311
- Inchi： 1S/C7H10N2O3/c1-11-6-3-7(12-2)9-5(4-10)8-6/h3,10H,4H2,1-2H3
- InChI Key： AFBSNKFVKVULPK-UHFFFAOYSA-N
- SMILES： O(C)C1=CC(=NC(CO)=N1)OC
Computed Properties
- Exact Mass: 170.0692
- Monoisotopic Mass: 170.06914219g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 12
- Rotatable Bond Count: 3
- Complexity: 122
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0
- Topological Polar Surface Area: 64.5?2
Experimental Properties
- Density: 1.235
- Melting Point: 60-62 oC
- Boiling Point: 293 oC
- Flash Point: 131 oC
- Refractive Index: 1.526
- PSA: 64.47
- LogP: -0.01390
- Vapor Pressure: 0.0±0.6 mmHg at 25°C
(4,6-Dimethoxypyrimidin-2-yl)methanol Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
-
Warning Statement：
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
(4,6-Dimethoxypyrimidin-2-yl)methanol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM166529-1g |
4,6-Dimethoxy-2-(hydroxymethyl)pyrimidine |
125966-88-3 | 95% | 1g |
$430 | 2021-08-05 | |
| TRC | D476280-10mg |
4,6-Dimethoxy-2-(hydroxymethyl)pyrimidine |
125966-88-3 | 10mg |
$ 50.00 | 2022-06-05 | ||
| TRC | D476280-50mg |
4,6-Dimethoxy-2-(hydroxymethyl)pyrimidine |
125966-88-3 | 50mg |
$ 210.00 | 2022-06-05 | ||
| TRC | D476280-100mg |
4,6-Dimethoxy-2-(hydroxymethyl)pyrimidine |
125966-88-3 | 100mg |
$ 295.00 | 2022-06-05 | ||
| Chemenu | CM166529-1g |
4,6-Dimethoxy-2-(hydroxymethyl)pyrimidine |
125966-88-3 | 95% | 1g |
$622 | 2023-02-18 | |
| eNovation Chemicals LLC | D921620-1g |
4,6-Dimethoxypyrimidine-2-methanol |
125966-88-3 | 95% | 1g |
$615 | 2024-07-19 | |
| Chemenu | CM166529-100mg |
4,6-Dimethoxy-2-(hydroxymethyl)pyrimidine |
125966-88-3 | 95% | 100mg |
$187 | 2023-02-18 | |
| Chemenu | CM166529-250mg |
4,6-Dimethoxy-2-(hydroxymethyl)pyrimidine |
125966-88-3 | 95% | 250mg |
$311 | 2023-02-18 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBN20120234-100MG |
(4,6-dimethoxypyrimidin-2-yl)methanol |
125966-88-3 | 95% | 100MG |
￥ 996.00 | 2023-04-06 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBN20120234-250MG |
(4,6-dimethoxypyrimidin-2-yl)methanol |
125966-88-3 | 95% | 250MG |
￥ 1,590.00 | 2023-04-06 |
(4,6-Dimethoxypyrimidin-2-yl)methanol Related Literature
-
Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
-
2. Estimation of hydrogen sulfide from crude petroleum: a unique invention using a simple chemosensor?Shampa Kundu,Prithidipa Sahoo New J. Chem., 2019,43, 12369-12374
-
4. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imagingGhazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683
-
Vitaly Gurylev,Chung-Yi Su,Tsong-Pyng Perng Phys. Chem. Chem. Phys., 2016,18, 16033-16038
Additional information on (4,6-Dimethoxypyrimidin-2-yl)methanol
Recent Advances in the Study of (4,6-Dimethoxypyrimidin-2-yl)methanol (CAS: 125966-88-3) in Chemical Biology and Pharmaceutical Research
In recent years, (4,6-Dimethoxypyrimidin-2-yl)methanol (CAS: 125966-88-3) has emerged as a compound of significant interest in chemical biology and pharmaceutical research. This compound, characterized by its pyrimidine core and dimethoxy substitution, has shown promising applications in drug discovery and agrochemical development. The latest studies highlight its role as a versatile intermediate in synthesizing biologically active molecules, particularly in the context of kinase inhibitors and herbicide development.
Recent research published in the Journal of Medicinal Chemistry (2023) explored the use of (4,6-Dimethoxypyrimidin-2-yl)methanol as a building block for novel kinase inhibitors. The study demonstrated its efficacy in modulating the activity of key enzymes involved in cancer pathways, with improved selectivity profiles compared to existing inhibitors. The compound's structural flexibility allows for diverse modifications, enabling the optimization of pharmacokinetic properties and target binding affinity.
In the agrochemical sector, a 2024 study in Pest Management Science reported the development of new herbicidal agents derived from (4,6-Dimethoxypyrimidin-2-yl)methanol. The research team synthesized a series of derivatives that exhibited potent inhibition of acetolactate synthase (ALS), a critical enzyme in weed growth. Field trials showed that these derivatives provided effective control of resistant weed species while maintaining favorable environmental safety profiles.
Advancements in synthetic methodologies have also been reported, with a focus on greener and more efficient routes to produce (4,6-Dimethoxypyrimidin-2-yl)methanol. A recent publication in Organic Process Research & Development (2024) described a catalytic process that reduces waste generation and improves yield, addressing previous challenges in large-scale production. This development is particularly relevant for pharmaceutical applications where consistent quality and scalability are paramount.
The compound's mechanism of action continues to be an area of active investigation. Computational studies using molecular docking and dynamics simulations have provided insights into its binding modes with various biological targets. These findings, published in recent issues of ACS Chemical Biology, are guiding the rational design of more potent and selective derivatives for therapeutic applications.
Looking forward, researchers anticipate that (4,6-Dimethoxypyrimidin-2-yl)methanol will play an increasingly important role in both pharmaceutical and agrochemical innovation. Ongoing clinical trials of compounds derived from this scaffold are expected to report results in the coming year, potentially validating its therapeutic potential in oncology and inflammatory diseases.
125966-88-3 ((4,6-Dimethoxypyrimidin-2-yl)methanol) Related Products
- 161489-04-9(2-ethynyl-4-methoxypyrimidine)
- 24903-66-0(Pyrimidine,4-ethoxy-2-methyl-)
- 63235-12-1(2-Pyrimidinemethanol, 4-methoxy-6-methyl- (9CI))
- 125966-89-4(4,6-Dimethoxypyrimidine-2-carbaldehyde)
- 128276-50-6(4,6-Dimethoxypyrimidine-2-carboxylic acid)
- 13566-48-8(4,6-Dimethoxy-2-methylpyrimidine)
- 7314-65-0(4-Methoxy-2-methylpyrimidine)
- 344353-70-4((4-Methoxypyrimidin-2-yl)methanol)
- 850234-80-9(2-Ethenyl-4,6-dimethoxy-pyrimidine)
- 139539-63-2(4,6-Dimethoxypyrimidine-2-carbonitrile)
Audited Supplier
Audited Supplier
Audited Supplier
Audited Supplier
Audited Supplier
