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• 3. Evidence of rutile-to-anatase photo-induced electron transfer in mixed-phase TiO2 by solid-state NMR spectroscopy?
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• 4. Establishment and implications of a characterization method for magnetic nanoparticle using cell tracking velocimetry and magnetic susceptibility modified solutions
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

Comprehensive Guide to 2-(4-chlorophenyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one (CAS No. 1258650-40-6): Properties, Applications, and Market Insights

2-(4-chlorophenyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one (CAS 1258650-40-6) is a specialized heterocyclic compound that has garnered significant attention in pharmaceutical and agrochemical research. This benzothiazole derivative features a unique molecular structure combining a chlorophenyl group with a tetrahydrobenzothiazolone core, making it valuable for various synthetic applications. Researchers frequently search for "benzothiazole synthesis methods" or "chlorophenyl heterocycle applications," reflecting the growing interest in this compound class.

The compound's physicochemical properties include a molecular weight of 265.74 g/mol and a purity typically exceeding 97%. Its structural features – particularly the 4-chlorophenyl substitution and saturated benzothiazole ring – contribute to its stability and reactivity profile. Recent studies exploring "heterocyclic compound drug discovery" highlight the importance of such scaffolds in developing new therapeutic agents, with 2-(4-chlorophenyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one serving as a key intermediate.

In pharmaceutical applications, this compound shows promise as a building block for kinase inhibitors and anti-inflammatory agents. The search trend for "small molecule drug intermediates" has increased by 35% year-over-year, reflecting the demand for compounds like CAS 1258650-40-6. Its molecular architecture allows for diverse modifications, making it valuable in medicinal chemistry optimization programs targeting various disease pathways.

The agrochemical sector utilizes 2-(4-chlorophenyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one in developing novel crop protection agents. With growing global concerns about "sustainable agriculture solutions," researchers are investigating its potential as a precursor for environmentally friendly pesticides. The compound's chlorinated aromatic system and heterocyclic core contribute to its bioactivity against various plant pathogens.

Market analysis reveals steady growth in demand for specialty benzothiazole derivatives, with CAS 1258650-40-6 showing particular promise. The compound's synthetic versatility and scalable production make it attractive for commercial applications. Industry reports tracking "fine chemical market trends" indicate increasing investment in such high-value intermediates across multiple sectors.

From a synthetic chemistry perspective, 2-(4-chlorophenyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one offers multiple reactivity sites for further functionalization. The ketone group at position 7 and the thiazole nitrogen provide handles for diverse chemical transformations. Recent publications on "heterocyclic compound modifications" frequently reference this structural motif due to its synthetic accessibility and structural diversity.

Quality control for CAS 1258650-40-6 typically involves HPLC analysis and spectroscopic characterization (1H NMR, 13C NMR, and mass spectrometry). The compound's chromatographic purity and structural integrity are critical parameters for research applications. Analytical chemists searching for "benzothiazole characterization methods" will find this compound's well-established analytical protocols particularly useful.

Environmental and toxicological assessments of 2-(4-chlorophenyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one indicate it requires standard laboratory handling precautions. While not classified as hazardous under current regulations, proper personal protective equipment should be used during manipulation. Safety data sheets provide detailed information about its handling requirements and storage conditions.

The future outlook for CAS 1258650-40-6 appears promising, particularly in drug discovery pipelines and agrochemical development. As research into "privileged structures in medicinal chemistry" continues to expand, the demand for such versatile heterocycles is expected to grow. The compound's structural features and demonstrated utility position it as an important research chemical with multiple potential applications.

For researchers investigating structure-activity relationships or developing new bioactive compounds, 2-(4-chlorophenyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one offers valuable opportunities. Its combination of aromatic chlorination and saturated heterocycle provides a unique pharmacophore template that continues to attract scientific interest across multiple disciplines.

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