Cas no 1257431-69-8 (2-Amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide)
2-Amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide is a boronic ester derivative of nicotinamide, primarily utilized as a key intermediate in Suzuki-Miyaura cross-coupling reactions. Its structure incorporates a stable dioxaborolane group, enhancing its reactivity and selectivity in palladium-catalyzed transformations. The compound is particularly valuable in pharmaceutical and agrochemical synthesis, where it facilitates the construction of complex heterocyclic frameworks. Its high purity and stability under standard handling conditions make it a reliable reagent for fine chemical applications. The presence of both amino and amide functionalities further expands its utility in derivatization and further functionalization processes. Proper storage under inert conditions is recommended to maintain its integrity.
1257431-69-8 structure
Product Name:2-Amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide
CAS No:1257431-69-8
MF:C13H20BN3O3
MW:277.127202987671
CID:5463414
Update Time:2025-06-07
2-Amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide Chemical and Physical Properties
Names and Identifiers
-
- 2-Amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide
- Z2050052580
- 2-amino-N-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-nicotinamide
- 2-amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide
- 2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide
- 3-Pyridinecarboxamide, 2-amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
-
- Inchi： 1S/C13H20BN3O3/c1-12(2)13(3,4)20-14(19-12)8-6-9(11(18)16-5)10(15)17-7-8/h6-7H,1-5H3,(H2,15,17)(H,16,18)
- InChI Key： NZFANPCJTCWJFS-UHFFFAOYSA-N
- SMILES： O1B(C2C=NC(=C(C(NC)=O)C=2)N)OC(C)(C)C1(C)C
Computed Properties
- Exact Mass: 277.1597717 g/mol
- Monoisotopic Mass: 277.1597717 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 20
- Rotatable Bond Count: 2
- Complexity: 373
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Molecular Weight: 277.13
- Topological Polar Surface Area: 86.5
2-Amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-7492297-0.05g |
2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide |
1257431-69-8 | 95% | 0.05g |
$600.0 | 2024-05-23 | |
| Enamine | EN300-7492297-0.1g |
2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide |
1257431-69-8 | 95% | 0.1g |
$783.0 | 2024-05-23 | |
| Enamine | EN300-7492297-0.25g |
2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide |
1257431-69-8 | 95% | 0.25g |
$1118.0 | 2024-05-23 | |
| Enamine | EN300-7492297-0.5g |
2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide |
1257431-69-8 | 95% | 0.5g |
$1760.0 | 2024-05-23 | |
| Enamine | EN300-7492297-1.0g |
2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide |
1257431-69-8 | 95% | 1.0g |
$2257.0 | 2024-05-23 | |
| Enamine | EN300-7492297-2.5g |
2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide |
1257431-69-8 | 95% | 2.5g |
$4424.0 | 2024-05-23 | |
| Enamine | EN300-7492297-5.0g |
2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide |
1257431-69-8 | 95% | 5.0g |
$6545.0 | 2024-05-23 | |
| Enamine | EN300-7492297-10.0g |
2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide |
1257431-69-8 | 95% | 10.0g |
$9704.0 | 2024-05-23 | |
| 1PlusChem | 1P028QEZ-50mg |
2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide |
1257431-69-8 | 95% | 50mg |
$804.00 | 2024-07-09 | |
| 1PlusChem | 1P028QEZ-100mg |
2-amino-N-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carboxamide |
1257431-69-8 | 95% | 100mg |
$1030.00 | 2024-07-09 |
2-Amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide Related Literature
-
Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
-
Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
-
Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
1257431-69-8 (2-Amino-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide) Related Products
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
- 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
- 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
- 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)
Recommended suppliers
Shanghai Hongxiang Biomedical Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Shenzhen Jianxing Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Reagent
Shanghai Jinhuan Chemical CO., LTD.
Gold Member
Audited Supplier
CN Supplier
Bulk
Nanjing Jubai Biopharm
Gold Member
Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
