Cas no 1257078-80-0 (4-Benzyloxy-3-methylphenylboronic acid pinacol ester)

4-Benzyloxy-3-methylphenylboronic acid pinacol ester is a boronic ester derivative commonly used in Suzuki-Miyaura cross-coupling reactions, a key method for forming carbon-carbon bonds in organic synthesis. The benzyloxy and methyl substituents on the phenyl ring enhance steric and electronic properties, making it a versatile intermediate for constructing complex aromatic frameworks. The pinacol ester group improves stability and handling compared to free boronic acids, reducing hydrolysis and facilitating storage. This compound is particularly valuable in pharmaceutical and materials science research, where controlled functionalization of aromatic systems is required. Its consistent reactivity and purity make it a reliable choice for synthetic applications.
4-Benzyloxy-3-methylphenylboronic acid pinacol ester structure
1257078-80-0 structure
Product Name:4-Benzyloxy-3-methylphenylboronic acid pinacol ester
CAS No:1257078-80-0
MF:C20H25BO3
MW:324.221706151962
CID:4565229
PubChem ID:68778515
Update Time:2025-06-08

4-Benzyloxy-3-methylphenylboronic acid pinacol ester Chemical and Physical Properties

Names and Identifiers

    • 2-(4-(benzyloxy)-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
    • 4-Benzyloxy-3-methylphenylboronic acid pinacol ester
    • 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-[3-methyl-4-(phenylmethoxy)phenyl]-
    • 4-Bnzyloxy-3-mthylphnylboronic acid pinacol str
    • DA-46628
    • 4,4,5,5-tetramethyl-2-(3-methyl-4-phenylmethoxyphenyl)-1,3,2-dioxaborolane
    • SCHEMBL3767677
    • MFCD18383421
    • CS-0178600
    • 2-(4-benzyloxy-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
    • 1257078-80-0
    • BS-30420
    • E97874
    • OVDZZKAGMVSQSX-UHFFFAOYSA-N
    • 2-[4-(BENZYLOXY)-3-METHYLPHENYL]-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
    • AKOS017552307
    • Inchi： 1S/C20H25BO3/c1-15-13-17(21-23-19(2,3)20(4,5)24-21)11-12-18(15)22-14-16-9-7-6-8-10-16/h6-13H,14H2,1-5H3
    • InChI Key： OVDZZKAGMVSQSX-UHFFFAOYSA-N
    • SMILES： O1C(C)(C)C(C)(C)OB1C1=CC=C(OCC2=CC=CC=C2)C(C)=C1

Computed Properties

  • Exact Mass: 324.1896748g/mol
  • Monoisotopic Mass: 324.1896748g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 24
  • Rotatable Bond Count: 4
  • Complexity: 401
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 27.7?2

Experimental Properties

  • Density: 1.1±0.1 g/cm3
  • Melting Point: Not available
  • Boiling Point: 443.6±40.0 °C at 760 mmHg
  • Flash Point: 222.1±27.3 °C
  • Vapor Pressure: 0.0±1.0 mmHg at 25°C

4-Benzyloxy-3-methylphenylboronic acid pinacol ester Security Information

4-Benzyloxy-3-methylphenylboronic acid pinacol ester Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM206812-1g
2-(4-(Benzyloxy)-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
 1257078-80-0 96%
1g
 $119 2021-08-04
Chemenu
CM206812-5g
2-(4-(Benzyloxy)-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
 1257078-80-0 96%
5g
 $436 2021-08-04
TRC
B410913-100mg
4-Benzyloxy-3-methylphenylboronic acid pinacol ester
 1257078-80-0
100mg
 $ 75.00 2023-04-18
TRC
B410913-250mg
4-Benzyloxy-3-methylphenylboronic acid pinacol ester
 1257078-80-0
250mg
 $ 144.00 2023-04-18
TRC
B410913-500mg
4-Benzyloxy-3-methylphenylboronic acid pinacol ester
 1257078-80-0
500mg
 $ 219.00 2023-04-18
TRC
B410913-1g
4-Benzyloxy-3-methylphenylboronic acid pinacol ester
 1257078-80-0
1g
 $ 250.00 2022-06-07
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
B886680-5g
2-(4-(benzyloxy)-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
 1257078-80-0 98%
5g
 2,160.00 2021-05-17
Chemenu
CM206812-1g
2-(4-(Benzyloxy)-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
 1257078-80-0 96%
1g
 $119 2022-06-13
Chemenu
CM206812-5g
2-(4-(Benzyloxy)-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
 1257078-80-0 96%
5g
 $*** 2023-03-29
TRC
B410913-1000mg
4-Benzyloxy-3-methylphenylboronic acid pinacol ester
 1257078-80-0
1g
 $ 305.00 2023-04-18

4-Benzyloxy-3-methylphenylboronic acid pinacol ester Related Literature

1257078-80-0 (4-Benzyloxy-3-methylphenylboronic acid pinacol ester) Related Products

Recommended suppliers
Henan Dongyan Pharmaceutical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Henan Dongyan Pharmaceutical Co., Ltd
Handan Zechi Trading Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shenzhen Yaoyuan R&D Center Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shenzhen Yaoyuan R&D Center Co.,Ltd
Hebei Liye chemical Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hebei Liye chemical Co.,Ltd
Nanjing Jubai Biopharm
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Nanjing Jubai Biopharm