Cas no 1256789-86-2 (5-fluoro-2-methoxypyridine-3-carbonitrile)

5-Fluoro-2-methoxypyridine-3-carbonitrile is a fluorinated pyridine derivative with a methoxy substituent at the 2-position and a nitrile group at the 3-position. This heterocyclic compound serves as a versatile intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of active ingredients. The presence of both electron-withdrawing (fluoro and nitrile) and electron-donating (methoxy) groups enhances its reactivity in cross-coupling reactions, nucleophilic substitutions, and cyclization processes. Its structural features make it valuable for constructing complex molecules with tailored biological activity. The compound exhibits high purity and stability under standard storage conditions, ensuring consistent performance in synthetic applications. Its well-defined reactivity profile facilitates precise functionalization in medicinal chemistry and material science research.

5-fluoro-2-methoxypyridine-3-carbonitrile structure

1256789-86-2 structure

Product Name:5-fluoro-2-methoxypyridine-3-carbonitrile

CAS No:1256789-86-2

MF:C₇H₅FN₂O

MW:152.125804662704

MDL:MFCD17214211

CID:1221808

PubChem ID:53395626

Update Time:2025-10-18

5-fluoro-2-methoxypyridine-3-carbonitrile Chemical and Physical Properties

Names and Identifiers

- 5-fluoro-2-methoxypyridine-3-carbonitrile
- 3-cyano-5-fluoro-2-methoxypyridine
- 1256789-86-2
- SY034095
- CS-0377282
- DB-315312
- 5-Fluoro-2-methoxynicotinonitrile
- AMY12499
- MFCD17214211
- AT41785
- DTXSID50694190
- SCHEMBL21412856
- MDL： MFCD17214211
- Inchi： 1S/C7H5FN2O/c1-11-7-5(3-9)2-6(8)4-10-7/h2,4H,1H3
- InChI Key： AFGMPWTXHJNZNP-UHFFFAOYSA-N
- SMILES： FC1=CN=C(C(C#N)=C1)OC

Computed Properties

Exact Mass: 152.03859095g/mol
Monoisotopic Mass: 152.03859095g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Heavy Atom Count: 11
Rotatable Bond Count: 1
Complexity: 177
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 1
Topological Polar Surface Area: 45.9?2

5-fluoro-2-methoxypyridine-3-carbonitrile Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Alichem	A029008841-250mg	5-Fluoro-2-methoxynicotinonitrile	1256789-86-2	95%	250mg	$940.80	2023-09-03
Alichem	A029008841-1g	5-Fluoro-2-methoxynicotinonitrile	1256789-86-2	95%	1g	$2808.15	2023-09-03
eNovation Chemicals LLC	Y1190032-1g	5-Fluoro-2-methoxynicotinonitrile	1256789-86-2	95%	1g	$1090	2025-02-20
Ambeed	A392950-1g	5-Fluoro-2-methoxynicotinonitrile	1256789-86-2	97%	1g	$989.0	2024-04-25
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.	1447952-1g	5-Fluoro-2-methoxynicotinonitrile	1256789-86-2	98%	1g	￥10029.00	2024-08-09
eNovation Chemicals LLC	Y1190032-1g	5-Fluoro-2-methoxynicotinonitrile	1256789-86-2	95%	1g	$1090	2024-07-20
eNovation Chemicals LLC	Y1190032-1g	5-Fluoro-2-methoxynicotinonitrile	1256789-86-2	95%	1g	$1090	2025-03-01

5-fluoro-2-methoxypyridine-3-carbonitrile Suppliers

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(CAS:1256789-86-2)5-Fluoro-2-methoxynicotinonitrile

Order Number:NC8208

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Quantity:10g

Purity:97%

Pricing Information Last Updated:Friday, 18 July 2025 16:16

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Additional information on 5-fluoro-2-methoxypyridine-3-carbonitrile

5-Fluoro-2-Methoxypyridine-3-Carbonitrile: A Comprehensive Overview

5-fluoro-2-methoxypyridine-3-carbonitrile (CAS No. 1256789-86-2) is a highly specialized organic compound that has garnered significant attention in the fields of chemistry, pharmacology, and materials science. This compound is characterized by its unique molecular structure, which includes a pyridine ring substituted with a fluorine atom at position 5, a methoxy group at position 2, and a cyano group at position 3. These substituents contribute to its distinctive chemical properties, making it a valuable molecule for various applications.

The synthesis of 5-fluoro-2-methoxypyridine-3-carbonitrile involves a series of intricate chemical reactions, often utilizing advanced methodologies such as Suzuki coupling or nucleophilic substitution. Recent advancements in catalytic processes have enabled the efficient and scalable production of this compound, which is crucial for its widespread use in research and industrial settings.

One of the most notable applications of 5-fluoro-2-methoxypyridine-3-carbonitrile is in the development of agrochemicals. Its ability to inhibit specific enzymes involved in plant growth regulation has made it a promising candidate for herbicides and fungicides. According to recent studies published in *Journal of Agricultural and Food Chemistry*, this compound exhibits high efficacy against various agricultural pests while maintaining low toxicity to non-target organisms.

In the pharmaceutical industry, 5-fluoro-2-methoxypyridine-3-carbonitrile has been explored as a potential lead compound for drug development. Its structural features allow for the modulation of pharmacokinetic properties, such as bioavailability and metabolic stability. Researchers at the University of California have reported that this compound shows potential in targeting oncogenic pathways, making it a subject of interest in anticancer drug discovery.

The electronic properties of 5-fluoro-2-methoxypyridine-3-carbonitrile also make it an attractive candidate for use in organic electronics. Its ability to act as an electron-deficient aromatic system has been leveraged in the development of advanced materials for solar cells and light-emitting diodes (LEDs). A study published in *Nature Communications* highlighted its role in enhancing the efficiency of organic photovoltaic devices through optimized charge transport mechanisms.

From an environmental perspective, the ecological impact of 5-fluoro-2-methoxypyridine-3-carbonitrile has been carefully evaluated to ensure sustainable practices. Regulatory agencies have established guidelines for its safe handling and disposal, ensuring minimal environmental footprint while maximizing its benefits across various industries.

In conclusion, 5-fluoro-2-methoxypyridine-3-carbonitrile (CAS No. 1256789-86-2) stands as a testament to the ingenuity and precision of modern chemical synthesis. Its versatility across multiple disciplines underscores its importance as a key molecule in contemporary scientific research and industrial applications.

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