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  Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
• 2. An approach to biodegradable star polymeric architectures using disulfide coupling?
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• 3. Alumina grafted SBA-15 sustainable bifunctional catalysts for direct cross-coupling of benzylic alcohols to diarylmethanes?
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• 4. An anti-ultrasonic-stripping effect in confined micro/nanoscale cavities and its applications for efficient multiscale metallic patterning?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Halobenzoic acids and derivatives

Professional Introduction to Compound with CAS No. 1255099-63-8 and Product Name: 2-BROMO-4-CHLORO-N-METHOXY-N-METHYLBENZAMIDE

The compound with the CAS number 1255099-63-8 and the product name 2-BROMO-4-CHLORO-N-METHOXY-N-METHYLBENZAMIDE represents a significant advancement in the field of chemical and pharmaceutical research. This compound, characterized by its unique structural and functional properties, has garnered considerable attention due to its potential applications in medicinal chemistry and drug development. The presence of both bromo and chloro substituents, combined with the methoxy and methylamido groups, endows this benzamide derivative with a versatile chemical profile that makes it a valuable candidate for further exploration.

In recent years, the pharmaceutical industry has witnessed a surge in the development of novel heterocyclic compounds, particularly those derived from benzamide scaffolds. These compounds are known for their broad spectrum of biological activities, including anti-inflammatory, antiviral, and anticancer properties. The specific arrangement of functional groups in 2-BROMO-4-CHLORO-N-METHOXY-N-METHYLBENZAMIDE contributes to its unique reactivity and interaction with biological targets. This has prompted researchers to investigate its potential as a lead compound for the synthesis of new therapeutic agents.

One of the most compelling aspects of this compound is its role as a building block in the synthesis of more complex molecules. The bromo and chloro substituents serve as excellent handles for further functionalization via cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings. These reactions are pivotal in constructing biaryl structures, which are prevalent in many bioactive compounds. Additionally, the methoxy and methylamido groups can be modified through various chemical transformations, allowing for the fine-tuning of biological activity.

Recent studies have highlighted the importance of benzamide derivatives in drug discovery. For instance, modifications at the amide nitrogen can significantly alter the pharmacokinetic properties of these compounds. The presence of both methoxy and methylamido groups in 2-BROMO-4-CHLORO-N-METHOXY-N-METHYLBENZAMIDE suggests that it may exhibit enhanced solubility and bioavailability compared to simpler benzamides. This is particularly relevant in the context of developing orally active drugs.

The compound's potential as an intermediate in medicinal chemistry has also been explored in several cutting-edge research projects. For example, researchers have utilized 2-BROMO-4-CHLORO-N-METHOXY-N-METHYLBENZAMIDE to synthesize novel inhibitors targeting specific enzymes involved in cancer metabolism. These inhibitors have shown promise in preclinical studies, demonstrating efficacy against various tumor types. The ability to modify the compound's structure allows for the optimization of potency and selectivity, which are critical factors in drug development.

Another area where this compound has shown promise is in the field of immunomodulation. Benzamide derivatives have been reported to modulate immune responses by interacting with receptors and signaling pathways involved in inflammation and immune regulation. The unique combination of functional groups in 2-BROMO-4-CHLORO-N-METHOXY-N-METHYLBENZAMIDE may enable it to interact with multiple targets simultaneously, leading to more comprehensive therapeutic effects.

The synthesis of 2-BROMO-4-CHLORO-N-METHOXY-N-METHYLBENZAMIDE itself is a testament to the advancements in synthetic organic chemistry. Modern techniques such as palladium-catalyzed cross-coupling reactions have made it possible to construct complex molecular frameworks with high precision and yield. These methods have not only facilitated the preparation of this compound but also opened up new avenues for its derivatives.

In conclusion, 2-BROMO-4-CHLORO-N-METHOXY-N-METHYLBENZAMIDE represents a significant contribution to the chemical and pharmaceutical landscape. Its unique structural features make it a versatile tool for drug discovery and molecular construction. As research continues to uncover new applications for this compound, it is likely that its importance will only grow, paving the way for innovative therapeutic strategies.

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