Cas no 125265-68-1 (Asiaticoside B)

Asiaticoside B is a triterpenoid saponin derived from Centella asiatica, known for its potential bioactive properties. It exhibits structural similarities to asiaticoside but with distinct molecular modifications that may influence its pharmacological activity. Research suggests Asiaticoside B may contribute to wound healing, anti-inflammatory, and antioxidant effects, though studies are ongoing to fully elucidate its mechanisms. Its high purity and standardized composition make it suitable for experimental applications in dermatology, cosmetics, and biomedical research. The compound is characterized by its stability and solubility in select solvents, facilitating its use in formulation studies. Further investigations are required to explore its therapeutic potential and comparative efficacy.
Asiaticoside B structure
Asiaticoside B structure
Product Name:Asiaticoside B
CAS No:125265-68-1
MF:C48H78O20
MW:975.12092
MDL:MFCD32197362
CID:2450254
PubChem ID:74962739
Update Time:2025-11-02

Asiaticoside B Chemical and Physical Properties

Names and Identifiers

    • Asiaticoside B
    • Terminoloside
    • (2alpha,3beta,4alpha,6beta)-2,3,6,23-Tetrahydroxy-olean-12-en-28-oic acid O-6-deoxy-alpha-L-mannopyranosyl-(1→4)-O-beta-D-glucopyranosyl-(1→6)-beta-D-glucopyranosyl ester
    • AKOS040760100
    • A929162
    • UNII-17E01H280E
    • HY-N5052
    • (2alpha,3beta,4alpha,6beta)-2,3,6,23-Tetrahydroxy-olean-12-en-28-oic acid O-6-deoxy-alpha-L-mannopyranosyl-(1-->4)-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester
    • Olean-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-o-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester, (2alpha,3beta,4alpha,6beta)-
    • 125265-68-1
    • ASIATICOSIDE B (CONSTITUENT OF CENTELLA ASIATICA) [DSC]
    • OLEAN-12-EN-28-OIC ACID, 2,3,6,23-TETRAHYDROXY-, O-6-DEOXY-.ALPHA.-L-MANNOPYRANOSYL-(1->4)-O-.BETA.-D-GLUCOPYRANOSYL-(1->6)-.BETA.-D-GLUCOPYRANOSYL ESTER, (2.ALPHA.,3.BETA.,4.ALPHA.,6.BETA.)-
    • D85110
    • DTXSID101317354
    • CHEBI:187486
    • MS-31826
    • CS-0032200
    • 17E01H280E
    • Q27251906
    • FT-0775992
    • DA-61257
    • ASIATICOSIDE B (CONSTITUENT OF CENTELLA ASIATICA)
    • MDL: MFCD32197362
    • Inchi: InChI=1S/C48H78O20/c1-20-28(53)30(55)33(58)40(64-20)67-36-25(17-49)65-39(35(60)32(36)57)63-18-26-29(54)31(56)34(59)41(66-26)68-42(62)48-12-10-43(2,3)14-22(48)21-8-9-27-44(4)15-24(52)38(61)45(5,19-50)37(44)23(51)16-47(27,7)46(21,6)11-13-48/h8,20,22-41,49-61H,9-19H2,1-7H3/t20-,22-,23+,24+,25+,26+,27+,28-,29+,30+,31-,32+,33+,34+,35+,36+,37+,38-,39+,40-,41-,44+,45-,46+,47+,48-/m0/s1
    • InChI Key: NNWMHSNRRWMMBI-PJISEHJASA-N
    • SMILES: CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OCC3C(C(C(C(O3)OC(=O)C45CCC(CC4C6=CCC7C8(CC(C(C(C8C(CC7(C6(CC5)C)C)O)(C)CO)O)O)C)(C)C)O)O)O)CO)O)O)O

Computed Properties

  • Exact Mass: 974.50864487 g/mol
  • Monoisotopic Mass: 974.50864487 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 13
  • Hydrogen Bond Acceptor Count: 20
  • Heavy Atom Count: 68
  • Rotatable Bond Count: 10
  • Complexity: 1870
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 26
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 975.1
  • XLogP3: -1.1
  • Topological Polar Surface Area: 335?2

Experimental Properties

  • Color/Form: No data available
  • Density: 1.47±0.1 g/cm3 (20 oC 760 Torr),
  • Melting Point: No data available
  • Boiling Point: 1040.5±65.0 °C at 760 mmHg
  • Flash Point: 294.8±27.8 °C
  • Solubility: Insuluble (4.9E-3 g/L) (25 oC),

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Asiaticoside B Suppliers

Amadis Chemical Company Limited
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(CAS:125265-68-1)Asiaticoside B
Order Number:A929162
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Quantity:10mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 14:56
Price ($):156.0
Hubei Cuiyuan Biotechnology Co.,Ltd
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Purity:≥98%
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Additional information on Asiaticoside B

Asiaticoside B (CAS No. 125265-68-1): A Comprehensive Overview of Its Properties and Applications

Asiaticoside B (CAS No. 125265-68-1) is a bioactive triterpenoid saponin derived from Centella asiatica, commonly known as Gotu Kola. This compound has garnered significant attention in recent years due to its potential therapeutic benefits, particularly in skincare, wound healing, and neuroprotection. With the growing interest in natural and plant-derived compounds, Asiaticoside B has become a focal point for researchers and industries alike.

The chemical structure of Asiaticoside B features a triterpene aglycone core attached to sugar moieties, which contributes to its unique biological activities. Studies have shown that this compound exhibits anti-inflammatory, antioxidant, and collagen-stimulating properties, making it a valuable ingredient in cosmetic and pharmaceutical formulations. Its ability to promote wound healing and skin regeneration has been particularly well-documented, aligning with the current consumer demand for natural skincare solutions.

In the realm of skincare, Asiaticoside B is often compared to its more well-known counterpart, Asiaticoside. However, recent research suggests that Asiaticoside B may offer distinct advantages, such as enhanced stability and bioavailability. This has led to its inclusion in high-end anti-aging creams, serums, and wound care products. The rise of "clean beauty" trends has further propelled the demand for plant-based actives like Asiaticoside B, as consumers seek safer and more sustainable alternatives to synthetic ingredients.

Beyond skincare, Asiaticoside B has shown promise in supporting cognitive health. Preliminary studies indicate that it may help protect neurons from oxidative stress and improve memory function, which aligns with the growing interest in nootropics and brain health supplements. While more research is needed, these findings have sparked curiosity among both scientists and health-conscious consumers.

The market for Asiaticoside B is expected to grow steadily, driven by the expanding cosmeceutical and nutraceutical industries. Manufacturers are increasingly focusing on sustainable extraction methods to meet the demand for high-purity Asiaticoside B while minimizing environmental impact. This reflects the broader shift toward eco-friendly and ethical sourcing practices in the botanical extract sector.

Quality control remains a critical consideration when working with Asiaticoside B. Advanced analytical techniques, such as HPLC and mass spectrometry, are employed to ensure the purity and consistency of this compound. These measures are essential for maintaining the efficacy and safety of products containing Asiaticoside B, especially in regulated markets.

For researchers and product developers, understanding the optimal conditions for Asiaticoside B stability is crucial. Factors such as pH, temperature, and light exposure can influence its performance in formulations. Recent innovations in encapsulation technologies have helped address these challenges, enabling more effective delivery of Asiaticoside B in various applications.

As interest in natural therapeutics continues to rise, Asiaticoside B stands out as a compound with multifaceted potential. Its applications span from dermatology to neurology, offering exciting opportunities for innovation. Future research will likely explore its mechanisms of action in greater depth, potentially uncovering new therapeutic avenues for this remarkable plant-derived molecule.

In conclusion, Asiaticoside B (CAS No. 125265-68-1) represents a fascinating intersection of traditional herbal medicine and modern scientific discovery. Its diverse biological activities and growing commercial relevance make it a compound worth watching in the coming years. As consumer preferences continue to evolve toward natural, evidence-based solutions, Asiaticoside B is poised to play an increasingly important role in health and wellness products worldwide.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:125265-68-1)Asiaticoside B
A929162
Purity:99%
Quantity:10mg
Price ($):156.0
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Hubei Cuiyuan Biotechnology Co.,Ltd
(CAS:125265-68-1)AsiaticosideB
CRN0550
Purity:≥98%
Quantity:5mg/20mg/50mg
Price ($):Inquiry
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