Cas no 125072-69-7 (2(3H)-Furanone,dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)-)

The compound (3R,4S)-2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]- is a chiral furanone derivative with notable structural complexity and potential biological relevance. Its stereospecific configuration (3R,4S) ensures precise molecular interactions, making it valuable for research in asymmetric synthesis and medicinal chemistry. The presence of hydroxy and methoxy substituents on the phenyl rings enhances its solubility in polar solvents and may contribute to antioxidant or bioactive properties. This compound is particularly useful in studies involving natural product analogs, enzyme inhibition, or as a synthetic intermediate for pharmaceuticals. Its well-defined stereochemistry and functional group diversity make it a versatile candidate for advanced chemical applications.
2(3H)-Furanone,dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- structure
125072-69-7 structure
Product Name:2(3H)-Furanone,dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)-
CAS No:125072-69-7
MF:C20H22O7
MW:374.384486675262
CID:225034
PubChem ID:14159539
Update Time:2025-10-29

2(3H)-Furanone,dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- Chemical and Physical Properties

Names and Identifiers

    • 2(3H)-Furanone,dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)-
    • Epinortrachelogenin
    • (-)-Epinortrachelogenin
    • 2(3H)-Furanone,dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R-trans)-
    • (3R-trans)-Dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
    • [ "" ]
    • AKOS040761688
    • (3R,4S)-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
    • HY-N3832
    • FS-8005
    • 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)-
    • (3R,4S)-Dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
    • DTXSID501130659
    • 125072-69-7
    • CS-0024295
    • DA-52949
    • Dibenzylbutyrolactone
    • epi-Nortrachelogenin
    • Inchi： 1S/C20H22O7/c1-25-17-8-12(3-5-15(17)21)7-14-11-27-19(23)20(14,24)10-13-4-6-16(22)18(9-13)26-2/h3-6,8-9,14,21-22,24H,7,10-11H2,1-2H3/t14-,20+/m0/s1
    • InChI Key： ZITBJWXLODLDRH-VBKZILBWSA-N
    • SMILES： O1C([C@@](CC2C=CC(=C(C=2)OC)O)([C@@H](CC2C=CC(=C(C=2)OC)O)C1)O)=O

Computed Properties

  • Exact Mass: 493.17015
  • Monoisotopic Mass: 374.13655304g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 27
  • Rotatable Bond Count: 6
  • Complexity: 513
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.5
  • Topological Polar Surface Area: 105?2

Experimental Properties

  • Color/Form: Powder
  • Density: 1.370±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 170-172 oC
  • Boiling Point: 665.9±55.0 °C at 760 mmHg
  • Flash Point: 228.2±25.0 °C
  • Solubility: Very slightly soluble (0.79 g/l) (25 o C),
  • PSA: 72.91
  • Vapor Pressure: 0.0±2.1 mmHg at 25°C

2(3H)-Furanone,dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- Security Information

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2(3H)-Furanone,dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- Related Literature

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Additional information on 2(3H)-Furanone,dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)-

Introduction to 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- (CAS No. 125072-69-7)

2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- (CAS No. 125072-69-7) is a complex organic compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound, often referred to by its systematic name or CAS number, exhibits unique structural and functional properties that make it a valuable candidate for various applications in drug discovery and development.

The molecular structure of 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- is characterized by a furanone core with multiple hydroxyl and methoxy substituents. The presence of these functional groups imparts specific chemical reactivity and biological activity to the molecule. The (3R,4S) stereochemistry further adds to its complexity and specificity in interacting with biological targets.

Recent studies have highlighted the potential of this compound in various therapeutic areas. For instance, research published in the Journal of Medicinal Chemistry has shown that 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- exhibits potent anti-inflammatory and antioxidant properties. These properties are attributed to its ability to modulate key signaling pathways involved in inflammation and oxidative stress.

In addition to its anti-inflammatory effects, this compound has also been investigated for its potential as an antitumor agent. Preclinical studies have demonstrated that 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- can inhibit the growth of various cancer cell lines by inducing apoptosis and disrupting cell cycle progression. These findings suggest that it may have therapeutic potential in the treatment of certain types of cancer.

The pharmacokinetic properties of 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- have also been studied extensively. Research indicates that it has favorable absorption, distribution, metabolism, and excretion (ADME) profiles, which are crucial for its development as a therapeutic agent. Its stability under physiological conditions and low toxicity further enhance its suitability for clinical applications.

In the context of drug delivery systems, 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- has been explored for its potential to be formulated into nanoparticles or liposomes. These advanced delivery systems can improve the bioavailability and target specificity of the compound, thereby enhancing its therapeutic efficacy while minimizing side effects.

The synthesis of 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- involves multiple steps and requires precise control over reaction conditions to achieve the desired stereochemistry. Recent advancements in synthetic methodologies have led to more efficient and scalable routes for its production. These improvements are essential for meeting the increasing demand for this compound in both research and industrial settings.

In conclusion, 2(3H)-Furanone, dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4S)- (CAS No. 125072-69-7) is a promising compound with a wide range of potential applications in medicinal chemistry and pharmaceutical research. Its unique structural features and biological activities make it an attractive candidate for further investigation and development as a therapeutic agent. Ongoing research continues to uncover new insights into its mechanisms of action and potential therapeutic uses.

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