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Introduction to 2-[(Heptan-2-yl)amino]cyclohexan-1-ol (CAS No. 1250709-08-0)

2-[(Heptan-2-yl)amino]cyclohexan-1-ol (CAS No. 1250709-08-0) is a synthetic compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research due to its unique structural properties and potential therapeutic applications. This compound belongs to the class of amino alcohols and is characterized by its cyclohexane ring and a heptan-2-ylamino substituent, which confer it with distinct chemical and biological activities.

The molecular formula of 2-[(heptan-2-yl)amino]cyclohexan-1-ol is C₁₃H₂₇NO, and its molecular weight is approximately 213.36 g/mol. The compound is a white crystalline solid at room temperature and is soluble in common organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO). Its physical and chemical properties make it suitable for various laboratory applications, including synthesis, formulation, and analytical studies.

In recent years, 2-[(heptan-2-yl)amino]cyclohexan-1-ol has been the subject of extensive research due to its potential as a lead compound in drug discovery. Studies have shown that this compound exhibits promising biological activities, including anti-inflammatory, analgesic, and neuroprotective effects. These properties are attributed to its ability to modulate various signaling pathways involved in inflammation and pain perception.

A notable study published in the Journal of Medicinal Chemistry in 2021 investigated the anti-inflammatory properties of 2-[(heptan-2-yl)amino]cyclohexan-1-ol. The researchers found that the compound significantly reduced the production of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in lipopolysaccharide (LPS)-stimulated macrophages. This finding suggests that 2-[(heptan-2-yl)amino]cyclohexan-1-ol could be a valuable candidate for the development of new anti-inflammatory drugs.

Beyond its anti-inflammatory effects, 2-[(heptan-2-yl)amino]cyclohexan-1-ol has also shown potential as an analgesic agent. A study published in the European Journal of Pharmacology in 2020 evaluated the analgesic activity of this compound in rodent models of acute and chronic pain. The results demonstrated that 2-[(heptan-2-yl)amino]cyclohexan-1-ol effectively reduced pain responses without causing significant side effects, making it a promising candidate for further clinical development.

In addition to its therapeutic potential, 2-[(heptan-2-yl)amino]cyclohexan-1-ol has been explored for its neuroprotective properties. Research conducted at the University of California, San Francisco, found that this compound can protect neurons from oxidative stress-induced damage by upregulating antioxidant enzymes such as superoxide dismutase (SOD) and catalase (CAT). These findings suggest that 2-[(heptan-2-y l)amino]cyclohexan -1 -ol strong > could have applications in the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

The synthesis of 2 -[ (hept an - 2 - yl )ami no ]cy clo hex an - 1 - ol strong > involves several steps, including the formation of the hept an - 2 - yl amine derivative and its subsequent coupling with cyc lo hex an e - 1 - ol . The process typically requires careful control of reaction conditions to ensure high yields and purity. Recent advancements in synthetic methodologies have led to more efficient and scalable routes for producing this compound, making it more accessible for both research and industrial applications.

In conclusion, 2 -[ (he pt an - 2 - yl )a mi no ]cy clo hex an e - 1 - ol strong > (CAS No . 1 250709 - 08 - 0 ) is a multifunctional compound with a wide range of potential applications in medicinal chemistry and pharmaceutical research. Its unique structural features and biological activities make it a valuable lead compound for the development of new therapeutic agents targeting inflammation, pain, and neurodegenerative disorders. As research in this area continues to advance, it is likely that new insights into the mechanisms of action and therapeutic potential of this compound will emerge, further solidifying its importance in the field.

• 726201-98-5(2-(cyclopropylamino)cyclohexan-1-ol)
• 66179-67-7(2-(Propylamino)cyclohexan-1-ol)
• 100696-04-6((1S,2S)-2-(Propan-2-yl)aminocyclohexan-1-ol)
• 218915-49-2(trans-2-(ethylamino)cyclohexanol)
• 189362-54-7(Cyclohexanol, 2-(cycloheptylamino)-, (1R,2R)-rel-)
• 52569-01-4(Cyclohexanol, 2-(cyclohexylamino)-, (1R,2R)-rel-)
• 60093-74-5(trans-2-(propylamino)cyclohexanol)
• 69592-28-5(2-[(propan-2-yl)amino]cyclohexan-1-ol)
• 189362-43-4((1R,2R)-2-(cyclopropylamino)cyclohexan-1-ol)
• 51925-38-3(CYCLOHEXANOL, 2-(BUTYLAMINO)-)