Cas no 1249253-32-4 (2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide)
2-Amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide is a brominated pyrazole derivative with a substituted propanamide backbone. This compound is of interest in medicinal chemistry and pharmaceutical research due to its structural features, which include a brominated heterocyclic core and a chiral amino-propanamide moiety. The presence of the bromine atom enhances its potential as a synthetic intermediate for further functionalization, while the pyrazole ring contributes to its stability and binding affinity in biological systems. Its unique structure makes it a candidate for the development of enzyme inhibitors or receptor modulators. The compound is typically handled under controlled conditions due to its reactive functional groups.
1249253-32-4 structure
Product Name:2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide
CAS No:1249253-32-4
MF:C9H15BrN4O
MW:275.145600557327
CID:5692297
PubChem ID:62130941
Update Time:2025-06-07
2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide Chemical and Physical Properties
Names and Identifiers
-
- 1H-Pyrazole-1-propanamide, α-amino-4-bromo-α,3,5-trimethyl-
- 2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide
-
- Inchi: 1S/C9H15BrN4O/c1-5-7(10)6(2)14(13-5)4-9(3,12)8(11)15/h4,12H2,1-3H3,(H2,11,15)
- InChI Key: QUUZLXLMNYPJNO-UHFFFAOYSA-N
- SMILES: BrC1C(C)=NN(C=1C)CC(C(N)=O)(C)N
Computed Properties
- Exact Mass: 274.04292g/mol
- Monoisotopic Mass: 274.04292g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 15
- Rotatable Bond Count: 3
- Complexity: 263
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: -0.1
- Topological Polar Surface Area: 86.9?2
Experimental Properties
- Density: 1.61±0.1 g/cm3(Predicted)
- Boiling Point: 429.8±45.0 °C(Predicted)
- pka: 15.54±0.50(Predicted)
2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-1123533-0.05g |
2-amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide |
1249253-32-4 | 95% | 0.05g |
$768.0 | 2023-10-26 | |
| Enamine | EN300-1123533-0.1g |
2-amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide |
1249253-32-4 | 95% | 0.1g |
$804.0 | 2023-10-26 | |
| Enamine | EN300-1123533-0.25g |
2-amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide |
1249253-32-4 | 95% | 0.25g |
$840.0 | 2023-10-26 | |
| Enamine | EN300-1123533-0.5g |
2-amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide |
1249253-32-4 | 95% | 0.5g |
$877.0 | 2023-10-26 | |
| Enamine | EN300-1123533-1.0g |
2-amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide |
1249253-32-4 | 1g |
$986.0 | 2023-06-09 | ||
| Enamine | EN300-1123533-2.5g |
2-amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide |
1249253-32-4 | 95% | 2.5g |
$1791.0 | 2023-10-26 | |
| Enamine | EN300-1123533-5.0g |
2-amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide |
1249253-32-4 | 5g |
$2858.0 | 2023-06-09 | ||
| Enamine | EN300-1123533-10.0g |
2-amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide |
1249253-32-4 | 10g |
$4236.0 | 2023-06-09 | ||
| Enamine | EN300-1123533-1g |
2-amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide |
1249253-32-4 | 95% | 1g |
$914.0 | 2023-10-26 | |
| Enamine | EN300-1123533-5g |
2-amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide |
1249253-32-4 | 95% | 5g |
$2650.0 | 2023-10-26 |
2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide Related Literature
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Hyejin Moon,Aaron R. Wheeler,Robin L. Garrell,Chang-Jin “CJ” Kim Lab Chip, 2006,6, 1213-1219
-
Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
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Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699
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Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
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