Cas no 1249253-32-4 (2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide)

2-Amino-3-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-2-methylpropanamide is a brominated pyrazole derivative with a substituted propanamide backbone. This compound is of interest in medicinal chemistry and pharmaceutical research due to its structural features, which include a brominated heterocyclic core and a chiral amino-propanamide moiety. The presence of the bromine atom enhances its potential as a synthetic intermediate for further functionalization, while the pyrazole ring contributes to its stability and binding affinity in biological systems. Its unique structure makes it a candidate for the development of enzyme inhibitors or receptor modulators. The compound is typically handled under controlled conditions due to its reactive functional groups.
2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide structure
1249253-32-4 structure
Product Name:2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide
CAS No:1249253-32-4
MF:C9H15BrN4O
MW:275.145600557327
CID:5692297
PubChem ID:62130941
Update Time:2025-06-07

2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide Chemical and Physical Properties

Names and Identifiers

    • 1H-Pyrazole-1-propanamide, α-amino-4-bromo-α,3,5-trimethyl-
    • 2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide
    • Inchi: 1S/C9H15BrN4O/c1-5-7(10)6(2)14(13-5)4-9(3,12)8(11)15/h4,12H2,1-3H3,(H2,11,15)
    • InChI Key: QUUZLXLMNYPJNO-UHFFFAOYSA-N
    • SMILES: BrC1C(C)=NN(C=1C)CC(C(N)=O)(C)N

Computed Properties

  • Exact Mass: 274.04292g/mol
  • Monoisotopic Mass: 274.04292g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 3
  • Complexity: 263
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.1
  • Topological Polar Surface Area: 86.9?2

Experimental Properties

  • Density: 1.61±0.1 g/cm3(Predicted)
  • Boiling Point: 429.8±45.0 °C(Predicted)
  • pka: 15.54±0.50(Predicted)

2-Amino-3-(4-bromo-3,5-dimethyl-1h-pyrazol-1-yl)-2-methylpropanamide Pricemore >>

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