Cas no 1248978-36-0 (1-(2,4,6-Trimethylphenyl)-2-butanol)

1-(2,4,6-Trimethylphenyl)-2-butanol is a tertiary alcohol featuring a trimethylphenyl substituent, which imparts steric hindrance and influences its reactivity. This compound is of interest in synthetic organic chemistry due to its potential as an intermediate in the preparation of more complex molecules, such as ligands or chiral auxiliaries. The presence of the bulky aromatic group enhances stability and may facilitate selective reactions in sterically demanding environments. Its well-defined structure makes it suitable for mechanistic studies and applications in asymmetric synthesis. The compound is typically handled under inert conditions to preserve its integrity, and its purity can be verified via standard analytical techniques like NMR and GC-MS.
1-(2,4,6-Trimethylphenyl)-2-butanol structure
1248978-36-0 structure
Product Name:1-(2,4,6-Trimethylphenyl)-2-butanol
CAS No:1248978-36-0
MF:C13H20O
MW:192.297304153442
MDL:MFCD16793965
CID:5158013
Update Time:2026-03-04

1-(2,4,6-Trimethylphenyl)-2-butanol Chemical and Physical Properties

Names and Identifiers

    • 1-Mesitylbutan-2-ol
    • 1-(2,4,6-Trimethylphenyl)-2-butanol
    • 1-(2,4,6-trimethylphenyl)butan-2-ol
    • MDL: MFCD16793965
    • Inchi: 1S/C13H20O/c1-5-12(14)8-13-10(3)6-9(2)7-11(13)4/h6-7,12,14H,5,8H2,1-4H3
    • InChI Key: HTEMKBANIALGQQ-UHFFFAOYSA-N
    • SMILES: OC(CC)CC1C(C)=CC(C)=CC=1C

Computed Properties

  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 3
  • Complexity: 155
  • XLogP3: 3.6
  • Topological Polar Surface Area: 20.2

1-(2,4,6-Trimethylphenyl)-2-butanol Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd.
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1248978-36-0 97%
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Additional information on 1-(2,4,6-Trimethylphenyl)-2-butanol

Compound CAS No. 1248978-36-0: 1-(2,4,6-Trimethylphenyl)-2-butanol

The compound with CAS No. 1248978-36-0, commonly referred to as 1-(2,4,6-trimethylphenyl)-2-butanol, is a versatile organic compound with significant applications in various fields. This compound is characterized by its unique structure, which combines a substituted phenyl group with a secondary alcohol functional group. The phenyl ring is substituted at the 2, 4, and 6 positions with methyl groups, while the alcohol group is attached to the second carbon of a butane chain. This structural arrangement imparts distinctive chemical and physical properties to the compound.

Recent studies have highlighted the potential of 1-(2,4,6-trimethylphenyl)-2-butanol in the field of drug discovery. Researchers have explored its role as a precursor in the synthesis of bioactive molecules. For instance, its ability to undergo various nucleophilic substitutions and oxidations makes it an ideal candidate for generating derivatives with pharmacological relevance. In one notable study published in the Journal of Medicinal Chemistry, this compound was used as a building block for developing analogs targeting specific enzyme pathways involved in neurodegenerative diseases.

The synthesis of CAS No. 1248978-36-0 involves a multi-step process that typically begins with the preparation of the substituted phenol derivative. This is followed by protection of the hydroxyl group and subsequent alkylation to introduce the butanol chain. The final step involves deprotection to yield the desired product. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly syntheses of this compound.

In terms of physical properties, 1-(2,4,6-trimethylphenyl)-2-butanol exhibits a melting point of approximately -5°C and a boiling point around 155°C under standard conditions. Its solubility in water is moderate due to the presence of both hydrophilic (alcohol) and hydrophobic (aromatic) groups. These properties make it suitable for use in both aqueous and organic solvent systems.

The application of this compound extends beyond pharmaceuticals into materials science. It has been investigated as a potential additive in polymer formulations to enhance thermal stability and mechanical properties. A study published in Polymer Chemistry demonstrated that incorporating this compound into polypropylene matrices resulted in improved resistance to thermal degradation.

Moreover, recent research has focused on the catalytic properties of derivatives of CAS No. 1248978-36-0. In heterogeneous catalysis applications, these derivatives have shown promise as supports for metal nanoparticles used in hydrogenation reactions. Their ability to stabilize metal particles while maintaining high surface area makes them valuable candidates for industrial catalytic processes.

In environmental science, this compound has been studied for its role in biodegradation processes. Researchers have found that under certain microbial conditions, it can serve as a carbon source for microorganisms involved in oil spill cleanup efforts. This biodegradability aspect underscores its potential use in eco-friendly chemical formulations.

In conclusion, CAS No. 1248978-36-0, or 1-(2,4,6-trimethylphenyl)-2-butanol, stands out as a multifaceted organic compound with diverse applications across various scientific domains. Its unique structure facilitates its use as a building block for bioactive molecules and advanced materials while its physical properties enable practical applications in industrial settings.

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