• 1. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?
  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
• 2. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
• 3. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
• 4. Evidence of pre-micellar aggregates in aqueous solution of amphiphilic PDMS–PEO block copolymer?
  Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
• 5. Emerging 2D hybrid nanomaterials: towards enhanced sensitive and selective conductometric gas sensors at room temperature
  Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenoxyacetic acid derivatives

Ethyl 2-(3,5-Dichloroquinolin-8-yloxy)acetate: A Comprehensive Overview

Ethyl 2-(3,5-Dichloroquinolin-8-yloxy)acetate, with CAS No. 1246819-05-5, is a highly specialized organic compound that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound is notable for its unique structure, which combines a quinoline ring system with ethoxy and acetate functionalities. The quinoline moiety, a heterocyclic aromatic compound, forms the core of this molecule, while the dichloro substitution pattern at positions 3 and 5 adds to its chemical complexity and potential biological activity.

The synthesis of Ethyl 2-(3,5-Dichloroquinolin-8-yloxy)acetate involves a series of precise chemical reactions, including nucleophilic substitution and esterification processes. The compound's structure is characterized by the presence of a chlorine atom at positions 3 and 5 of the quinoline ring, which contributes to its stability and reactivity. The ethoxy group attached to the quinoline ring further enhances its solubility in organic solvents, making it suitable for various applications in research and development.

Recent studies have highlighted the potential of Ethyl 2-(3,5-Dichloroquinolin-8-yloxy)acetate as a precursor for the development of novel pharmaceutical agents. Its biological activity has been explored in several in vitro assays, where it has shown promising results in inhibiting key enzymes associated with inflammatory diseases. The compound's ability to modulate cellular signaling pathways makes it a valuable tool in drug discovery efforts targeting conditions such as arthritis and neurodegenerative disorders.

In addition to its pharmacological applications, Ethyl 2-(3,5-Dichloroquinolin-8-yloxy)acetate has also found utility in materials science. Researchers have investigated its use as a building block for constructing advanced materials with tailored electronic properties. The compound's aromaticity and substituent effects make it an ideal candidate for designing molecules with specific photophysical properties, which could be exploited in optoelectronic devices.

The latest advancements in computational chemistry have further deepened our understanding of Ethyl 2-(3,5-Dichloroquinolin-8-yloxy)acetate's molecular behavior. Quantum mechanical calculations have revealed insights into its electronic structure and reactivity patterns, providing a foundation for rational drug design strategies. These studies underscore the importance of this compound as a versatile building block in modern chemical research.

In conclusion, Ethyl 2-(3,5-Dichloroquinolin-8-yloxy)acetate represents a fascinating example of how structural complexity can lead to diverse functional applications. Its unique combination of quinaldic acid derivatives, chlorine substitution, and ester functionalities positions it as a key molecule in both academic and industrial settings. As research continues to uncover new dimensions of its potential, this compound is poised to play an increasingly significant role in advancing scientific knowledge and technological innovation.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)