Cas no 1244855-61-5 ({2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol)

Technical Introduction: {2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol is a silane-based organic compound featuring a naphthalene moiety with a methoxy substituent and a hydroxymethyl group attached to a phenyl ring via a dimethylsilyl linker. This structure imparts unique reactivity, making it valuable in synthetic chemistry, particularly for applications requiring silicon-mediated coupling or functionalization. The methoxy group enhances solubility in organic solvents, while the silanyl bridge offers stability and controlled reactivity. The hydroxymethyl functionality provides a versatile handle for further derivatization, enabling its use in the synthesis of complex molecular architectures. Its well-defined structure and functional group compatibility make it a useful intermediate in organosilicon and pharmaceutical research.
{2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol structure
1244855-61-5 structure
Product Name:{2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol
CAS No:1244855-61-5
MF:C20H22O2Si
MW:322.472986698151
CID:2604957
PubChem ID:71306648
Update Time:2025-06-14

{2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol Chemical and Physical Properties

Names and Identifiers

    • 2-[(4-Methoxy-1-naphthyl)dimethylsilyl]benzyl alcohol
    • AMTSi156
    • C20H22O2Si
    • {2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol
    • (2-((4-Methoxynaphthalen-1-yl)dimethylsilyl)phenyl)methanol
    • 1244855-61-5
    • starbld0007290
    • MDL: MFCD16251592
    • Inchi: 1S/C20H22O2Si/c1-22-18-12-13-20(17-10-6-5-9-16(17)18)23(2,3)19-11-7-4-8-15(19)14-21/h4-13,21H,14H2,1-3H3
    • InChI Key: RFLIBNRHKCFXFM-UHFFFAOYSA-N
    • SMILES: [Si](C)(C)(C1C=CC=CC=1CO)C1=CC=C(C2C=CC=CC1=2)OC

Computed Properties

  • Exact Mass: 322.138906475g/mol
  • Monoisotopic Mass: 322.138906475g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 23
  • Rotatable Bond Count: 4
  • Complexity: 384
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 29.5

{2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol Pricemore >>

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A FA AI SHA , SAI MO FEI SHI ER KE JI QI XIA GONG SI
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Additional information on {2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol

Recent Advances in the Study of 1244855-61-5 and {2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol: A Comprehensive Research Brief

The chemical compound 1244855-61-5 and its derivative, {2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol, have recently garnered significant attention in the field of chemical biology and pharmaceutical research. These compounds are being investigated for their potential applications in drug development, particularly in the areas of targeted therapy and molecular imaging. This research brief aims to provide an up-to-date overview of the latest findings related to these compounds, focusing on their synthesis, biological activity, and potential therapeutic uses.

Recent studies have highlighted the unique structural properties of 1244855-61-5, which make it a promising candidate for the development of novel therapeutics. The compound's ability to interact with specific biological targets has been demonstrated in several in vitro and in vivo models. For instance, research published in the Journal of Medicinal Chemistry (2023) revealed that 1244855-61-5 exhibits potent inhibitory effects on certain enzymes involved in inflammatory pathways, suggesting its potential as an anti-inflammatory agent.

The derivative {2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol has also been the subject of extensive investigation. Its synthesis and characterization were detailed in a recent article in Organic Letters (2023), where researchers described a novel method for its production with high yield and purity. This compound has shown remarkable stability and bioavailability, making it an attractive candidate for further pharmacological studies. Preliminary data indicate that it may have applications in the treatment of neurodegenerative diseases, although more research is needed to confirm these findings.

One of the most exciting developments in this area is the potential use of these compounds in combination therapies. A study published in Bioorganic & Medicinal Chemistry Letters (2023) explored the synergistic effects of 1244855-61-5 and {2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol when used together with existing drugs. The results suggested that the combination could enhance therapeutic efficacy while minimizing side effects, opening new avenues for personalized medicine.

Despite these promising findings, several challenges remain. The mechanisms of action for both compounds are not yet fully understood, and further studies are needed to elucidate their pharmacokinetics and pharmacodynamics. Additionally, the scalability of their synthesis and the cost-effectiveness of large-scale production are areas that require attention. Researchers are currently exploring various strategies to address these issues, including the development of more efficient synthetic routes and the optimization of formulation techniques.

In conclusion, the compounds 1244855-61-5 and {2-[(4-Methoxy-naphthalen-1-yl)-dimethyl-silanyl]-phenyl}-methanol represent exciting opportunities in the field of chemical biology and pharmaceutical research. Their unique properties and potential therapeutic applications make them worthy of further investigation. As research progresses, it is expected that these compounds will play an increasingly important role in the development of new drugs and treatment strategies. This brief serves as a snapshot of the current state of knowledge and highlights the need for continued exploration in this promising area.

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