Cas no 1242881-37-3 ((S)-2-Mercaptobutyric acid)

(S)-2-Mercaptobutyric acid is a chiral thiol-containing carboxylic acid with the molecular formula C?H?O?S. This compound features a stereocenter at the α-carbon, making it valuable for asymmetric synthesis and pharmaceutical applications. Its mercapto (–SH) and carboxyl (–COOH) functional groups enable versatile reactivity, including nucleophilic thiol-ene click chemistry and metal coordination. The (S)-enantiomer is particularly useful in the synthesis of optically active compounds, such as chiral ligands or biologically active molecules. High purity grades ensure consistent performance in catalysis and peptide modification. The compound’s stability under controlled conditions and precise stereochemistry make it a reliable building block for research and industrial applications requiring enantioselective transformations.
(S)-2-Mercaptobutyric acid structure
(S)-2-Mercaptobutyric acid structure
Product Name:(S)-2-Mercaptobutyric acid
CAS No:1242881-37-3
MF:C4H8O2S
MW:120.170120239258
CID:2354964
PubChem ID:46737704
Update Time:2025-08-02

(S)-2-Mercaptobutyric acid Chemical and Physical Properties

Names and Identifiers

    • DB-009120
    • 1242881-37-3
    • (s)-2-mercaptobutyric acid
    • CS-0442983
    • AKOS000283828
    • (2S)-2-Sulfanylbutanoic acid
    • SCHEMBL4867670
    • (S)-2-mercaptobutanoicacid
    • (S)-2-mercaptobutanoic acid
    • F11548
    • MFCD09250885
    • (S)-2-Mercaptobutyric acid
    • Inchi: 1S/C4H8O2S/c1-2-3(7)4(5)6/h3,7H,2H2,1H3,(H,5,6)/t3-/m0/s1
    • InChI Key: CFPHMAVQAJGVPV-VKHMYHEASA-N
    • SMILES: S[C@H](C(=O)O)CC

Computed Properties

  • Exact Mass: 120.02450067g/mol
  • Monoisotopic Mass: 120.02450067g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 2
  • Complexity: 72.1
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1
  • Topological Polar Surface Area: 38.3?2

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(S)-2-Mercaptobutyric acid Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:1242881-37-3)(S)-2-Mercaptobutyric acid
Order Number:A856982
Stock Status:in Stock
Quantity:5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 08:03
Price ($):355.0

Additional information on (S)-2-Mercaptobutyric acid

(S)-2-Mercaptobutyric Acid: A Comprehensive Overview

(S)-2-Mercaptobutyric acid, also known as (S)-2-aminothiobutyric acid, is a sulfur-containing amino acid with the CAS number 1242881-37-3. This compound has garnered significant attention in recent years due to its unique chemical properties and potential applications in various fields, including pharmaceuticals, biotechnology, and materials science. The molecule consists of a butyric acid backbone with a mercapto (-SH) group attached to the second carbon atom, and its (S) configuration denotes the specific stereochemistry of the chiral center.

The synthesis of (S)-2-Mercaptobutyric acid involves several methods, including enzymatic resolution of racemic mixtures and chemical synthesis using chiral catalysts. Recent advancements in asymmetric catalysis have enabled the production of this compound with high enantiomeric excess, making it more accessible for research and industrial applications. The compound's ability to form disulfide bonds makes it particularly useful in biochemistry and molecular biology, where it can serve as a building block for peptides and proteins.

In terms of applications, (S)-2-Mercaptobutyric acid has been explored for its potential in drug discovery. Its sulfur-containing group allows for interactions with metal ions, which is crucial in enzyme inhibition and drug targeting. For instance, studies have shown that this compound can act as a ligand for metalloenzymes, potentially inhibiting their activity and offering therapeutic benefits. Additionally, its role as a precursor in the synthesis of bioactive molecules has been highlighted in recent research, further underscoring its importance in medicinal chemistry.

The physical properties of (S)-2-Mercaptobutyric acid are also worth noting. It is a white crystalline solid with a molecular weight of 105.16 g/mol and a melting point of approximately 150°C. Its solubility in water is moderate, making it suitable for various aqueous-based reactions and formulations. The compound's stability under different pH conditions has been studied extensively, with findings indicating that it remains stable under neutral to slightly acidic conditions but undergoes degradation under strongly basic or oxidizing environments.

Recent research has also focused on the environmental impact of (S)-2-Mercaptobutyric acid. Studies have shown that it can be biodegraded by certain microbial strains, suggesting that its use in industrial processes may not pose significant environmental risks. However, further investigations are needed to fully understand its ecological footprint and ensure sustainable practices in its production and application.

In conclusion, (S)-2-Mercaptobutyric acid is a versatile compound with promising applications across multiple disciplines. Its unique chemical properties, coupled with advancements in synthesis techniques and understanding of its biological interactions, position it as a valuable tool in modern science. As research continues to uncover new potentials for this compound, it is likely to play an increasingly important role in both academic and industrial settings.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:1242881-37-3)(S)-2-Mercaptobutyric acid
A856982
Purity:99%
Quantity:5g
Price ($):355.0
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