• 1. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 2. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
• 3. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
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• 4. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Bromobenzenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Halobenzenes Bromobenzenes

1-(3-Bromophenyl)cyclopropane-1-carbonitrile: A Comprehensive Overview

1-(3-Bromophenyl)cyclopropane-1-carbonitrile, identified by the CAS registry number 124276-83-1, is a unique organic compound that has garnered significant attention in the fields of synthetic chemistry, pharmacology, and materials science. This compound is characterized by its cyclopropane ring fused with a cyano group and a bromophenyl substituent, making it a versatile building block for various chemical transformations. Recent studies have highlighted its potential in drug discovery, particularly in the development of bioactive molecules with tailored properties.

The structure of 1-(3-Bromophenyl)cyclopropane-1-carbonitrile consists of a cyclopropane ring, which is known for its high ring strain and reactivity. The cyano group attached to the cyclopropane ring introduces electron-withdrawing effects, enhancing the compound's reactivity in various chemical reactions. The bromophenyl group at the 3-position adds further complexity to the molecule, providing opportunities for regioselective substitution reactions. This combination of structural features makes it an attractive candidate for exploring novel synthetic pathways and applications.

Recent advancements in synthetic chemistry have enabled the efficient synthesis of 1-(3-Bromophenyl)cyclopropane-1-carbonitrile. One notable approach involves the use of transition metal catalysts to facilitate coupling reactions between aryl bromides and cyclopropane derivatives. These methods not only improve the yield but also allow for precise control over the stereochemistry of the product. The development of such strategies has significantly expanded the scope of this compound in both academic and industrial settings.

In terms of physical properties, 1-(3-Bromophenyl)cyclopropane-1-carbonitrile exhibits a melting point of approximately 85°C and a boiling point around 250°C under standard conditions. Its solubility in common organic solvents such as dichloromethane and acetonitrile makes it suitable for various laboratory applications. The compound's stability under thermal and oxidative conditions has also been extensively studied, revealing its potential for use in high-temperature chemical processes.

The application of 1-(3-Bromophenyl)cyclopropane-1-carbonitrile spans across multiple disciplines. In pharmacology, it serves as a valuable intermediate in the synthesis of bioactive compounds, particularly those targeting cancer and neurodegenerative diseases. Recent research has demonstrated its ability to modulate key cellular pathways, making it a promising lead compound for drug development. Additionally, its unique electronic properties make it an ideal candidate for applications in organic electronics, such as in the fabrication of semiconducting materials.

In conclusion, 1-(3-Bromophenyl)cyclopropane-1-carbonitrile, with its distinctive structure and versatile reactivity, continues to be a focal point in contemporary chemical research. Its role as a building block in organic synthesis, coupled with its potential applications in pharmacology and materials science, underscores its significance in advancing scientific knowledge and technological innovation.

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• 99057-81-5(2-(4-Bromophenyl)butanenitrile)
• 124276-67-1(1-(4-bromophenyl)cyclopropane-1-carbonitrile)
• 1236193-08-0(1-(3,5-dibromophenyl)cyclopropane-1-carbonitrile)
• 118255-97-3(3-(3-bromophenyl)-2,2-dimethylpropanenitrile)
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• 676138-32-2(1-(3-broMophenyl)cyclohexanecarbonitrile)
• 99677-54-0(Cyclobutanecarbonitrile, 4-(3-bromophenyl)-2,2,3,3-tetramethyl-, trans-)