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• 2. Dilithiation of arenetricarbonylchromium(0) complexes with enantioselective quench: application to chiral biaryl synthesis
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• 3. Weak intermolecular interactions and molecular aggregation in isostructural dihaloperfluoroethanes,
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  Anna Olejniczak,Andrzej Katrusiak,Ashwani Vij CrystEngComm 2009 11 1073
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Recent Advances in the Study of 1,2-Dibromotetrafluoroethane (CAS: 124-73-2) in Chemical and Biomedical Applications

1,2-Dibromotetrafluoroethane (CAS: 124-73-2) is a halogenated hydrocarbon with significant applications in chemical synthesis, material science, and biomedical research. Recent studies have explored its unique physicochemical properties, including its high stability, low toxicity, and reactivity, which make it a valuable compound for various industrial and scientific purposes. This research brief synthesizes the latest findings on 1,2-dibromotetrafluoroethane, focusing on its synthesis, applications, and potential implications for the chemical and biomedical fields.

One of the key areas of recent research has been the optimization of synthetic routes for 1,2-dibromotetrafluoroethane. A 2023 study published in the Journal of Fluorine Chemistry demonstrated a novel catalytic method for its production, which significantly reduces energy consumption and byproduct formation. The study highlighted the use of palladium-based catalysts to achieve higher yields and purity, addressing previous challenges in large-scale synthesis. This advancement is particularly relevant for industries requiring high-purity halogenated compounds for specialized applications.

In the biomedical field, 1,2-dibromotetrafluoroethane has garnered attention for its potential as a contrast agent in medical imaging. A recent preprint on bioRxiv explored its use in X-ray imaging, where its high electron density and biocompatibility were leveraged to enhance image contrast. Preliminary results indicated superior performance compared to traditional iodine-based agents, with reduced side effects and improved patient tolerance. Further clinical trials are underway to validate these findings and assess long-term safety profiles.

Environmental and toxicological studies have also been a focus, given the compound's persistence in ecosystems. A 2024 report by the Environmental Protection Agency (EPA) evaluated the biodegradability and ecotoxicity of 1,2-dibromotetrafluoroethane. The findings suggested that while the compound exhibits low acute toxicity, its long-term environmental impact warrants careful monitoring. Researchers recommended the development of degradation protocols to mitigate potential risks, particularly in industrial settings where accidental releases may occur.

Looking ahead, interdisciplinary collaborations are expected to drive further innovations involving 1,2-dibromotetrafluoroethane. Its versatility in chemical reactions and compatibility with biomedical systems positions it as a promising candidate for emerging technologies, such as drug delivery systems and advanced materials. However, challenges remain in balancing its industrial utility with environmental and health considerations, necessitating ongoing research and regulatory oversight.

• 430-90-0(1-bromo-1,2,2-trifluoroethane)
• 354-04-1(1,2-Dibromo-1,1,2-trifluoroethane)
• 52434-78-3(Ethyl, 2-bromo-1,1,2,2-tetrafluoro-)
• 354-07-4(Ethane,1-bromo-1,1,2,2-tetrafluoro-)
• 511228-62-9(ETHYLIUM, 2-BROMO-1,1,2,2-TETRAFLUORO-)
• 420-92-8(ETHANE, 1-BROMO-1,1,2-TRIFLUORO-)
• 75-82-1(1,2-Dibromo-1,1-difluoroethane)
• 354-55-2(1-bromo-1,1,2,2,2-pentafluoroethane)
• 31392-96-8(Ethane,dibromodifluoro- (7CI,9CI))
• 509101-43-3(OXONIUM, COMPD. WITH 1,2-DIBROMO-1,1,2,2-TETRAFLUOROETHANE (1:1))