Cas no 123855-25-4 (Benzenamine,3,5-difluoro-N,N-dimethyl-)

Benzenamine, 3,5-difluoro-N,N-dimethyl-, is a fluorinated aromatic amine derivative characterized by its dimethylamino and difluoro substituents on the benzene ring. This compound is of interest in synthetic organic chemistry due to its electron-rich amine group and the electronic effects imparted by the fluorine atoms, which can influence reactivity and stability. The presence of fluorine enhances lipophilicity and metabolic stability, making it a potential intermediate in pharmaceuticals and agrochemicals. Its structural features allow for further functionalization, enabling applications in cross-coupling reactions and as a building block for more complex molecules. The compound is typically handled under controlled conditions due to its amine functionality.

Benzenamine,3,5-difluoro-N,N-dimethyl- structure

123855-25-4 structure

Product Name:Benzenamine,3,5-difluoro-N,N-dimethyl-

CAS No:123855-25-4

MF:C₈H₉F₂N

MW:157.16056895256

CID:103978

PubChem ID:10702072

Update Time:2025-06-07

Benzenamine,3,5-difluoro-N,N-dimethyl- Chemical and Physical Properties

Names and Identifiers

- Benzenamine,3,5-difluoro-N,N-dimethyl-
- 3,5-Difluoro-N,N-dimethylaniline
- Benzenamine, 3,5-difluoro-N,N-dimethyl- (9CI)
- N,N-dimethyl-3,5-difluoroaniline
- FS-4994
- 123855-25-4
- AKOS006346688
- SB75752
- SCHEMBL6225564
- LSFWPIDPPNCVHV-UHFFFAOYSA-N
- BENZENAMINE, 3,5-DIFLUORO-N,N-DIMETHYL-
- DTXSID10443641
- MDL： MFCD15530342
- Inchi： 1S/C8H9F2N/c1-11(2)8-4-6(9)3-7(10)5-8/h3-5H,1-2H3
- InChI Key： LSFWPIDPPNCVHV-UHFFFAOYSA-N
- SMILES： FC1C=C(C=C(C=1)N(C)C)F

Computed Properties

Exact Mass: 157.07037
Monoisotopic Mass: 157.07030562g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Heavy Atom Count: 11
Rotatable Bond Count: 1
Complexity: 117
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 2.2
Topological Polar Surface Area: 3.2?2

Experimental Properties

PSA: 3.24

Benzenamine,3,5-difluoro-N,N-dimethyl- Pricemore >>

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Fluorochem	043426-1g	3,5-Difluoro-N,N-dimethylaniline	123855-25-4	98%	1g	￡24.00	2022-02-28
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eNovation Chemicals LLC	Y1250577-25g	Benzenamine, 3,5-difluoro-N,N-dimethyl-	123855-25-4	98%	25g	$1995	2024-06-08
eNovation Chemicals LLC	Y1250577-100g	Benzenamine, 3,5-difluoro-N,N-dimethyl-	123855-25-4	98%	100g	$4895	2024-06-08
1PlusChem	1P000LN7-250mg	Benzenamine, 3,5-difluoro-N,N-dimethyl-	123855-25-4	98%	250mg	$69.00	2025-02-18
1PlusChem	1P000LN7-1g	Benzenamine, 3,5-difluoro-N,N-dimethyl-	123855-25-4	98%	1g	$110.00	2025-02-18
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Benzenamine,3,5-difluoro-N,N-dimethyl- Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:123855-25-4)3,5-Difluoro-N,N-dimethylaniline

Order Number:LE7878

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 11:58

Price ($):discuss personally

Email:[email protected]

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Related Categories

Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Amines Tertiary amines

Additional information on Benzenamine,3,5-difluoro-N,N-dimethyl-

Comprehensive Overview of Benzenamine,3,5-difluoro-N,N-dimethyl- (CAS No. 123855-25-4): Properties, Applications, and Industry Insights

Benzenamine,3,5-difluoro-N,N-dimethyl- (CAS No. 123855-25-4) is a fluorinated aromatic amine derivative with significant relevance in pharmaceutical and agrochemical research. This compound, characterized by its dimethylamino and difluoro substituents, exhibits unique electronic properties that make it valuable for designing advanced materials and bioactive molecules. Its molecular structure (C₈H₁₀F₂N) enables applications in drug discovery, catalysis, and organic electronics, aligning with current trends in sustainable chemistry and precision synthesis.

In recent years, the demand for fluorinated compounds like 3,5-difluoro-N,N-dimethylaniline has surged due to their role in developing FDA-approved drugs and crop protection agents. Researchers frequently search for "CAS 123855-25-4 solubility" or "synthesis of difluorinated anilines," reflecting its technical importance. The compound’s lipophilicity and metabolic stability—enhanced by fluorine atoms—are critical for optimizing bioavailability in medicinal chemistry, a topic dominating 2024’s pharma R&D discussions.

From an industrial perspective, Benzenamine,3,5-difluoro-N,N-dimethyl- serves as a key intermediate in cross-coupling reactions, particularly in palladium-catalyzed processes. Its compatibility with green chemistry protocols (e.g., solvent-free reactions) addresses environmental concerns, a priority for modern manufacturers. Analytical data shows peaks at δ 2.85 ppm (N-CH₃) and δ 6.45–6.70 ppm (aromatic protons) in ¹H-NMR, aiding quality control—a detail often queried in patent literature and academic databases.

Emerging applications include its use in OLED materials, where the electron-donating dimethylamino group improves charge transport efficiency. This aligns with global interest in energy-efficient displays, as evidenced by search trends for "fluorinated amines in optoelectronics." Regulatory agencies classify it as non-hazardous under standard handling conditions, though proper PPE is recommended during synthesis—a point emphasized in SDS documentation.

Future prospects for CAS 123855-25-4 involve AI-driven molecular design, where its scaffold is optimized via machine learning algorithms—a hot topic in cheminformatics forums. Suppliers should note the compound’s stability under inert atmospheres (storage queries rank high in procurement searches), while researchers value its ≥98% HPLC purity for reproducible results. As industries shift toward halogenated building blocks, this compound’s versatility ensures sustained demand across life sciences and material engineering sectors.

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