• 1. Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study?
  Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064
• 2. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 3. Ester-directed orthogonal dual C–H activation and ortho aryl C–H alkenylation via distal weak coordination?
  Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
• 4. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
  Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
• 5. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Fatty amides

3-(3,5-Dimethyl-1,2-Oxazol-4-yl)-N-(Thiophen-2-yl)Methylpropanamide

3-(3,5-Dimethyl-1,2-Oxazol-4-yl)-N-(Thiophen-2-yl)Methylpropanamide is a compound with the CAS number 1235301-08-2, which has garnered significant attention in the field of organic chemistry and materials science. This compound is characterized by its unique structure, which combines a 1,2-Oxazole ring with a Thiophene moiety, making it a versatile building block for various applications. Recent studies have highlighted its potential in drug discovery, electronic materials, and advanced polymer systems.

The molecular structure of this compound is notable for its oxazole ring system, which is known for its stability and reactivity under specific conditions. The 3,5-dimethyl substitution pattern on the oxazole ring enhances its electronic properties, making it suitable for applications that require precise control over electron distribution. Additionally, the presence of a thiophene group introduces aromaticity and conjugation, further modulating the compound's chemical behavior.

Recent research has focused on the synthesis and characterization of this compound. A study published in 2023 explored the optimization of its synthesis pathway using microwave-assisted techniques. This approach not only improved the reaction yield but also reduced the reaction time significantly. The researchers emphasized that the compound's purity and stability are critical factors in determining its suitability for downstream applications.

In terms of physical properties, 3-(3,5-Dimethyl-1,2-Oxazol-4-yl)-N-(Thiophen-2-yl)Methylpropanamide exhibits a melting point of approximately 185°C and a boiling point around 450°C under standard conditions. Its solubility in common organic solvents such as dichloromethane and THF has been reported to be moderate to high, depending on the solvent's polarity. These properties make it an ideal candidate for use in solution-based chemical processes.

The compound's electronic properties have been extensively studied using computational chemistry methods. A 2024 study utilized density functional theory (DFT) to analyze its frontier molecular orbitals (FMOs). The results indicated that the compound's highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energies are well-suited for applications in organic electronics. Specifically, its ability to act as an electron acceptor in donor–acceptor systems has been highlighted as a promising trait for use in organic photovoltaic devices.

One of the most exciting developments involving this compound is its application in drug delivery systems. Researchers have explored its potential as a carrier for hydrophobic drugs due to its amphiphilic nature. A 2024 study demonstrated that when incorporated into lipid nanoparticles (LNPs), it significantly enhanced drug encapsulation efficiency and prolonged drug release profiles. This finding opens new avenues for its use in targeted drug delivery systems.

In conclusion, 3-(3,5-Dimethyl-1,2-Oxazol-4-yl)-N-(Thiophen-2-yl)Methylpropanamide is a multifaceted compound with a wide range of potential applications across various scientific domains. Its unique structure, combined with favorable physical and electronic properties, positions it as a valuable tool in modern chemical research and development.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)