Cas no 1227599-35-0 ((6-Bromo-2-chloropyridin-3-yl)methanol)

(6-Bromo-2-chloropyridin-3-yl)methanol is a halogenated pyridine derivative with a hydroxymethyl functional group at the 3-position, making it a versatile intermediate in organic synthesis and pharmaceutical applications. The presence of both bromo and chloro substituents enhances its reactivity, enabling selective cross-coupling reactions such as Suzuki or Buchwald-Hartwig amination. The hydroxymethyl group offers further derivatization potential, facilitating esterification, oxidation, or etherification. This compound is particularly valuable in the development of agrochemicals, pharmaceuticals, and functional materials due to its balanced reactivity and stability. High purity grades ensure consistent performance in demanding synthetic pathways. Proper handling under inert conditions is recommended to preserve its integrity.
(6-Bromo-2-chloropyridin-3-yl)methanol structure
1227599-35-0 structure
Product Name:(6-Bromo-2-chloropyridin-3-yl)methanol
CAS No:1227599-35-0
MF:C6H5BrClNO
MW:222.466999769211
MDL:MFCD16606991
CID:1038518
PubChem ID:70701001
Update Time:2025-10-28

(6-Bromo-2-chloropyridin-3-yl)methanol Chemical and Physical Properties

Names and Identifiers

    • (6-Bromo-2-chloropyridin-3-yl)methanol
    • EN300-2163967
    • AT21654
    • MFCD16606991
    • A890981
    • CS-0192628
    • GTAIWEUPYUVFOX-UHFFFAOYSA-N
    • DTXSID20743780
    • 3-Pyridinemethanol, 6-bromo-2-chloro-
    • 1227599-35-0
    • SCHEMBL15940510
    • MDL: MFCD16606991
    • Inchi: 1S/C6H5BrClNO/c7-5-2-1-4(3-10)6(8)9-5/h1-2,10H,3H2
    • InChI Key: GTAIWEUPYUVFOX-UHFFFAOYSA-N
    • SMILES: BrC1=CC=C(C(=N1)Cl)CO

Computed Properties

  • Exact Mass: 220.92400
  • Monoisotopic Mass: 220.92430g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 114
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2
  • Topological Polar Surface Area: 33.1?2

Experimental Properties

  • PSA: 33.12000
  • LogP: 1.98980

(6-Bromo-2-chloropyridin-3-yl)methanol Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Additional information on (6-Bromo-2-chloropyridin-3-yl)methanol

Introduction to (6-Bromo-2-chloropyridin-3-yl)methanol (CAS No: 1227599-35-0)

The compound (6-Bromo-2-chloropyridin-3-yl)methanol, identified by the CAS number 1227599-35-0, is a highly specialized organic molecule with significant applications in various fields, particularly in the pharmaceutical and agricultural industries. This compound is characterized by its unique structure, which includes a pyridine ring substituted with bromine and chlorine atoms at positions 6 and 2, respectively, along with a hydroxymethyl group at position 3.

Recent advancements in synthetic chemistry have enabled the efficient synthesis of (6-Bromo-2-chloropyridin-3-yl)methanol through a variety of methods, including multi-component reactions and catalytic processes. These methods have not only improved the yield but also enhanced the purity of the compound, making it more suitable for high-value applications.

The structural uniqueness of (6-Bromo-2-chloropyridin-3-yl)methanol contributes to its remarkable biological activity, particularly in inhibiting certain enzymes and receptors that are critical in disease pathways. For instance, studies have shown that this compound exhibits potent anti-inflammatory and antioxidant properties, which are being explored for potential use in treating chronic diseases such as arthritis and neurodegenerative disorders.

In the agricultural sector, (6-Bromo-2-chloropyridin-3-yl)methanol has gained attention for its role as a precursor in the synthesis of novel pesticides and herbicides. Its ability to target specific pests without adversely affecting non-target species has made it a valuable asset in sustainable agriculture practices.

Moreover, recent research has focused on the environmental impact of (6-Bromo-2-chloropyridin-3-yL)methanol and its degradation products. Studies indicate that under certain conditions, the compound can degrade into non-toxic byproducts, reducing its environmental footprint.

In conclusion, (6-Bromo-2-chloropyridin-XL)methanol (CAS No: 1227599-XL-X) is a versatile compound with promising applications across multiple industries. Its unique structure, coupled with advancements in synthetic methods and biological studies, positions it as a key player in future innovations in medicine and agriculture.

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