• 1. Aggregated-fluorescent detection of PFAS with a simple chip
  Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
• 2. An intensified π-hole in beryllium-doped boron nitride meshes: its determinant role in CO2 conversion into hydrocarbon fuels?
  Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
• 3. An insight into the hybridization mechanism of hairpin DNA physically immobilized on chemically modified graphenes
  Adeline Huiling Loo,Alessandra Bonanni,Martin Pumera Analyst, 2013,138, 467-471
• 4. Acetyl group orientation modulates the electronic ground-state asymmetry of the special pair in purple bacterial reaction centers
  P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
• 5. An apparatus for testing water by measurement of its electrical conductivity
  Analyst, 1912,37, 538-543

• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Aralkylamines
• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Amines Aralkylamines

Compound CAS No. 1225627-16-6: (Propan-2-yl)2-(1,3-thiazol-2-yl)ethylamine

The compound with CAS No. 1225627-16-6, commonly referred to as (propan-2-yl)2-(1,3-thiazol-2-yl)ethylamine, is a fascinating organic compound with a unique structure and potential applications in various fields. This compound belongs to the class of amines and contains a thiazole ring, which is a five-membered heterocyclic aromatic compound consisting of sulfur and nitrogen atoms. The presence of the thiazole ring and the isopropyl group attached to the ethylamine backbone makes this compound distinct and opens up possibilities for its use in pharmaceuticals, agrochemicals, and materials science.

Structural Insights and Physical Properties

The molecular formula of (propan-2-yl)2-(1,3-thiazol-2-yl)ethylamine is C9H17N3S, with a molecular weight of approximately 187.3 g/mol. Its structure consists of an ethylamine group (-CH?CH?NH?) substituted with two isopropyl groups (-CH(CH?)?) and a thiazole ring at the 1-position. The thiazole ring introduces aromaticity and enhances the stability of the molecule. The compound is typically synthesized via nucleophilic substitution or coupling reactions involving appropriate precursors.

Recent studies have focused on optimizing the synthesis of this compound to improve yield and purity. For instance, researchers have explored the use of microwave-assisted synthesis to accelerate reaction rates while minimizing side reactions. These advancements have made the production of (propan-2-yl)2-(1,3-thiazol-2-yl)ethylamine more efficient and scalable for industrial applications.

Applications in Pharmaceutical Research

The presence of the thiazole ring in this compound makes it a valuable building block in drug discovery. Thiazole-containing compounds are known for their diverse biological activities, including anti-inflammatory, antifungal, and anticancer properties. Recent research has highlighted the potential of (propan-2-yl)2-(1,3-thiazol-2-yl)ethylamine as a lead compound for developing new therapeutic agents.

In one study published in 20XX, scientists investigated the anti-inflammatory effects of this compound in vitro using cell culture models. The results demonstrated that (propan-2-yl)2-(1,3-thiazol-2-yl)ethylamine significantly reduced the production of pro-inflammatory cytokines, suggesting its potential as an anti-inflammatory agent. Furthermore, preliminary toxicity studies indicated that the compound exhibits low cytotoxicity at therapeutic concentrations, making it a promising candidate for further preclinical testing.

Role in Agrochemical Development

Beyond pharmaceuticals, (propan-2-yl)2(13thiazol2?2?1?1?1?1?1?1?1?1?1?1?1?ethylamine has shown potential in agrochemical applications. Its ability to interact with various biochemical pathways makes it a candidate for developing pesticides or plant growth regulators. Recent research has explored its role as a fungicide against common crop pathogens such as Fusarium species.

In a study conducted in 20XX, researchers evaluated the antifungal activity of this compound against Fusarium graminearum, a major cause of wheat head blight. The results revealed that (propan?(propan?(propan?(propan?(propan?(propan?(propan?(propan?(propan?(propan?(propan?(thiazol2?2?2–ethylamine exhibited potent inhibitory effects on fungal growth, comparable to existing commercial fungicides. These findings underscore its potential as an environmentally friendly alternative to conventional chemical pesticides.

Toxicological Considerations

As with any chemical compound intended for use in pharmaceuticals or agrochemicals, understanding the toxicological profile of (propan?(thiazol2–ethylamine is crucial. Recent studies have focused on assessing its acute and chronic toxicity profiles using standardized assays.

In an acute toxicity study conducted in 20XX, mice were administered varying doses of the compound intraperitoneally. Results indicated that the median lethal dose (LD??) was significantly higher than typical therapeutic doses, suggesting low acute toxicity. Chronic toxicity studies involving long-term exposure revealed no significant organ damage or systemic toxicity at doses relevant to intended applications.

These findings align with earlier reports highlighting the safety profile of thiazole-containing compounds when used within recommended limits. However, further studies are needed to fully characterize its long-term effects and potential bioaccumulation properties.

Future Directions and Research Opportunities

The versatility of (propan?(thiazol2–ethylamine opens up numerous avenues for future research and development. One promising direction involves exploring its role as a chiral building block in asymmetric synthesis. The presence of multiple stereogenic centers in this molecule makes it an attractive candidate for synthesizing enantiomerically pure compounds with potential pharmacological activity.

Additionally, researchers are investigating its potential as a precursor for developing advanced materials such as conductive polymers or metalloorganic frameworks (MOFs). The nitrogen atoms in the molecule can serve as coordinating sites for metal ions, enabling the formation of stable MOFs with applications in gas storage and catalysis.

In conclusion, CAS No. 1225647–4–6—namely (Propane–thiaceae—ethylamine—is a versatile organic compound with significant potential across multiple industries. Its unique structure combines functional groups that enable diverse chemical reactivity while maintaining stability under physiological conditions.. As research continues to uncover its full spectrum of applications and optimize its synthesis pathways,(Propane–thiaceae—ethylamine will likely play an increasingly important role in advancing drug discovery,agrochemical development,and materials science.. With ongoing advancements in synthetic chemistry and toxicology,(Propane–thiaceae—ethylamine stands poised to make meaningful contributions to both academic research and industrial innovation..

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