Cas no 1225462-33-8 ((R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride)
(R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride Chemical and Physical Properties
Names and Identifiers
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- (R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride
- (1R)-1-[6-(trifluoromethyl)pyridin-3-yl]etanamine hydrochloride salt
- (1r)-1-[6-(trifluoromethyl)pyridin-3-yl]ethanamine hydrochloride salt
- (R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethan-1-amine xhydrochloride
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- Inchi: 1S/C8H9F3N2.ClH/c1-5(12)6-2-3-7(13-4-6)8(9,10)11;/h2-5H,12H2,1H3;1H/t5-;/m1./s1
- InChI Key: ZBMTZZVOKNNAIC-NUBCRITNSA-N
- SMILES: Cl.FC(C1=CC=C(C=N1)[C@@H](C)N)(F)F
Computed Properties
- Exact Mass: 226.0484605 g/mol
- Monoisotopic Mass: 226.0484605 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 14
- Rotatable Bond Count: 1
- Complexity: 169
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 38.9
- Molecular Weight: 226.62
(R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FD02030-5g |
(1R)-1-[6-(trifluoromethyl)pyridin-3-yl]ethanamine.HCl |
1225462-33-8 | 95% | 5g |
$2989 | 2023-09-07 |
(R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride Related Literature
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
Additional information on (R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride
Compound CAS No. 1225462-33-8: (R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine Hydrochloride
The compound (R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride with CAS No. 1225462-33-8 is a highly specialized chemical entity that has garnered significant attention in the fields of pharmaceutical chemistry and materials science. This compound is characterized by its unique structure, which combines a pyridine ring substituted with a trifluoromethyl group and an ethanamine moiety, all under the influence of an (R)-configuration. The hydrochloride salt form further enhances its stability and solubility properties, making it a valuable compound for various applications.
Recent studies have highlighted the potential of (R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride in drug discovery, particularly in the development of novel therapeutic agents targeting specific biological pathways. The trifluoromethyl group attached to the pyridine ring imparts unique electronic and steric properties, which are crucial for optimizing the compound's bioavailability and pharmacokinetics. Researchers have demonstrated that this compound exhibits promising activity in preclinical models, suggesting its potential as a lead molecule for treating conditions such as neurodegenerative diseases and inflammatory disorders.
The synthesis of (R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride involves a multi-step process that combines principles from organic synthesis and asymmetric catalysis. The key steps include the construction of the pyridine ring with precise substitution patterns, followed by the introduction of the trifluoromethyl group and the ethanamine side chain. The use of chiral catalysts ensures the high enantiomeric excess required for obtaining the (R)-configuration, which is critical for the compound's biological activity.
In terms of applications, (R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride has shown versatility across multiple domains. In pharmaceuticals, it serves as a building block for constructing more complex molecules with enhanced therapeutic profiles. Additionally, its electronic properties make it a candidate for use in advanced materials, such as organic semiconductors and sensors. Recent advancements in nanotechnology have also explored its potential as a stabilizing agent in nanoparticle formulations.
The latest research on (R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride has focused on understanding its interaction with biological systems at the molecular level. Computational studies have provided insights into its binding affinities with key proteins, while experimental studies have validated these findings through in vitro assays. These efforts have underscored the compound's potential as a modulator of cellular signaling pathways, offering new avenues for therapeutic intervention.
In conclusion, (R)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine hydrochloride represents a cutting-edge chemical entity with diverse applications across multiple scientific disciplines. Its unique structure, combined with advanced synthetic methodologies and promising biological activity, positions it as a valuable tool for researchers in academia and industry alike. As ongoing studies continue to unravel its full potential, this compound is poised to make significant contributions to the advancement of science and technology.
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