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Comprehensive Guide to Cyclopentanecarboxylic acid, 2-hydroxy-, methyl ester, (1R-cis)- (9CI) (CAS No. 122331-02-6)

Cyclopentanecarboxylic acid, 2-hydroxy-, methyl ester, (1R-cis)- (9CI) is a specialized organic compound with significant applications in pharmaceuticals, fragrances, and fine chemicals. This compound, identified by CAS No. 122331-02-6, is a chiral ester derivative of cyclopentanecarboxylic acid, featuring a hydroxyl group at the 2-position and a methyl ester functionality. Its unique stereochemistry, denoted by the (1R-cis) configuration, makes it a valuable intermediate in asymmetric synthesis and drug development.

The molecular structure of Cyclopentanecarboxylic acid, 2-hydroxy-, methyl ester, (1R-cis)- (9CI) contributes to its versatility in chemical reactions. The presence of both hydroxyl and ester groups allows for further functionalization, making it a key building block in organic synthesis. Researchers and manufacturers often seek this compound for its ability to introduce cyclopentane rings into complex molecules, a feature highly valued in medicinal chemistry.

In the pharmaceutical industry, CAS No. 122331-02-6 has gained attention as a precursor for bioactive molecules. Its chiral nature aligns with the growing demand for enantiomerically pure drugs, a trend driven by stricter regulatory requirements and the need for safer medications. The compound's potential in developing antiviral and anti-inflammatory agents is currently under investigation, reflecting the industry's focus on novel therapeutic solutions.

The fragrance and flavor sector also utilizes Cyclopentanecarboxylic acid, 2-hydroxy-, methyl ester, (1R-cis)- (9CI) due to its ability to contribute unique olfactory characteristics. As consumers increasingly seek distinctive and sustainable scent profiles, this compound offers formulators a tool to create innovative fragrance compositions. Its biodegradability and potential natural origin (through synthetic biology approaches) make it particularly interesting for eco-conscious product development.

From a synthetic chemistry perspective, the (1R-cis) configuration of this molecule presents interesting challenges and opportunities. Recent advances in enzymatic synthesis and biocatalysis have improved production efficiency, addressing common queries about sustainable manufacturing processes for chiral compounds. These developments align with the chemical industry's broader shift toward green chemistry principles.

Market analysis indicates growing interest in Cyclopentanecarboxylic acid derivatives, with CAS No. 122331-02-6 being no exception. The compound's applications in high-value sectors have driven research into more cost-effective production methods. Suppliers are increasingly offering custom synthesis services for this material, responding to demand from pharmaceutical companies and research institutions.

Quality control for Cyclopentanecarboxylic acid, 2-hydroxy-, methyl ester, (1R-cis)- (9CI) typically involves chiral HPLC analysis to ensure enantiomeric purity, a critical parameter for most applications. Analytical methods development for this compound remains an active area of research, as evidenced by numerous recent publications. These technical aspects frequently appear in search queries from quality assurance professionals and researchers.

The stability profile of CAS No. 122331-02-6 under various storage conditions is another common topic of inquiry. Proper handling recommendations include protection from moisture and storage at controlled temperatures to maintain the compound's integrity. Such practical information is highly sought after by laboratory technicians and process chemists working with this material.

In academic circles, Cyclopentanecarboxylic acid, 2-hydroxy-, methyl ester, (1R-cis)- (9CI) serves as an excellent case study for teaching stereochemistry and retrosynthetic analysis. Its structure provides multiple learning points about conformational analysis, functional group interconversion, and asymmetric synthesis strategies. Educational applications contribute to steady demand from universities and research institutes.

Looking forward, the applications of Cyclopentanecarboxylic acid derivatives are expected to expand further. Emerging research explores their potential in materials science, particularly in the development of specialty polymers with unique properties. This diversification aligns with the compound's inherent structural flexibility and functional group compatibility.

For researchers considering CAS No. 122331-02-6 for their projects, thorough literature review is recommended. The compound's synthetic utility has been documented in various contexts, offering valuable insights for new applications. Recent patent activity suggests growing commercial interest, particularly in pharmaceutical applications where its chiral properties provide competitive advantages.

Safety considerations for Cyclopentanecarboxylic acid, 2-hydroxy-, methyl ester, (1R-cis)- (9CI) follow standard laboratory protocols for organic compounds. While not classified as hazardous under normal handling conditions, proper personal protective equipment and ventilation are advised when working with this material. These precautions address common safety-related search queries about the compound.

The global supply chain for Cyclopentanecarboxylic acid derivatives has become more robust in recent years, with multiple suppliers now offering CAS No. 122331-02-6 at various purity grades. This availability supports research and development activities across different industries, from small-scale academic investigations to industrial-scale production.

In conclusion, Cyclopentanecarboxylic acid, 2-hydroxy-, methyl ester, (1R-cis)- (9CI) represents a versatile chiral building block with growing importance across multiple scientific and industrial domains. Its unique structural features and synthetic utility continue to attract research interest, while commercial applications expand in response to market needs. As synthetic methodologies advance and new applications emerge, this compound is poised to maintain its relevance in chemical research and development.

• 182683-23-4(Cyclopentanecarboxylicacid, 2-hydroxy-5-methyl-, methyl ester, (1R,2S,5S)-rel-)
• 172825-21-7(Cyclopentanecarboxylic acid, 2-hydroxy-1-methyl-, methyl ester, (1R-trans)-)
• 124150-22-7(Cyclopentanecarboxylicacid, 2-hydroxy-, methyl ester, (1R,2R)-)
• 933-92-6(Methyl 2-hydroxycyclopentanecarboxylate)
• 124150-23-8(Cyclopentanecarboxylicacid, 2-hydroxy-, methyl ester, (1S,2R)-)
• 170234-09-0(Cyclopentanecarboxylic acid, 2-hydroxy-3-methyl-, methyl ester, (1alpha,2beta,3alpha)-)
• 122332-63-2(Cyclopentanecarboxylicacid, 2-hydroxy-, methyl ester, (1S,2S)-)
• 172825-20-6(Cyclopentanecarboxylic acid, 2-hydroxy-1-methyl-, methyl ester, (1S-trans)-)
• 820236-45-1(Cyclopentanecarboxylic acid, 3-(1,1-dimethylethyl)-2-hydroxy-, methylester)
• 63358-33-8(Cyclopentanecarboxylic acid, 2,3-dihydroxy-, methyl ester, (1-alpha-,2-alpha-,3-alpha-)- (9CI))