Cas no 1220616-44-3 (Rebaudioside M)

Rebaudioside M (Reb M) is a high-intensity, non-caloric sweetener derived from the leaves of the Stevia rebaudiana plant. As a steviol glycoside, it exhibits superior sweetness potency—approximately 200–350 times sweeter than sucrose—while maintaining a clean, sugar-like taste profile with minimal bitterness or aftertaste compared to other stevia extracts. Reb M is heat-stable and pH-stable, making it suitable for a wide range of food and beverage applications. Its low glycemic impact and non-cariogenic properties align with dietary and health-conscious formulations. The compound is typically produced via enzymatic bioconversion or fermentation, ensuring scalability and purity for industrial use. Regulatory approvals in key markets further support its commercial viability.
Rebaudioside M structure
Rebaudioside M structure
Product Name:Rebaudioside M
CAS No:1220616-44-3
MF:C56H90O33
MW:1291.29402208328
CID:1078784
Update Time:2025-10-28

Rebaudioside M Chemical and Physical Properties

Names and Identifiers

    • REBAUDIOSIDE M(P)
    • Rebaudioside M
    • (4alpha)-13-[(O-beta-D-Glucopyranosyl-(1→2)-O-[beta-D-glucopyranosyl-(1→3)]-beta-D-glucopyranosyl)oxy]-kaur-16-en-18-oic acid O-beta-D-glucopyranosyl-(1→2)-O-[beta-D-glucopyranosyl-(1→3)]-beta-D-glucopyranosyl ester
    • Rebaudioside X
    • [5-Hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxan-2-yl
    • FQA8XMC4XJ
    • Q63393666
    • Reb M
    • Reb X
    • Reb-M
    • Reb-X
    • Fema No. 4895
    • Fema No. 4922
    • s3282
    • Inchi: 1S/C56H90O33/c1-19-11-55-9-5-26-53(2,7-4-8-54(26,3)52(77)88-50-44(86-48-40(75)36(71)30(65)22(14-59)80-48)42(32(67)24(16-61)82-50)84-46-38(73)34(69)28(63)20(12-57)78-46)27(55)6-10-56(19,18-55)89-51-45(87-49-41(76)37(72)31(66)23(15-60)81-49)43(33(68)25(17-62)83-51)85-47-39(74)35(70)29(64)21(13-58)79-47/h20-51,57-76H,1,4-18H2,2-3H3
    • InChI Key: GSGVXNMGMKBGQU-UHFFFAOYSA-N
    • SMILES: C1(C(O)C(O)C(O)C(CO)O1)OC1C(OC2C(O)C(O)C(O)C(CO)O2)C(OC(C2(C3CCC45CC(CCC4C3(C)CCC2)(OC2C(OC3C(O)C(O)C(O)C(CO)O3)C(OC3C(O)C(O)C(O)C(CO)O3)C(O)C(CO)O2)C(=C)C5)C)=O)OC(CO)C1O

Computed Properties

  • Exact Mass: 1290.5364353 g/mol
  • Monoisotopic Mass: 1290.5364353 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 20
  • Hydrogen Bond Acceptor Count: 33
  • Heavy Atom Count: 89
  • Rotatable Bond Count: 19
  • Complexity: 2400
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 36
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -6
  • Topological Polar Surface Area: 532
  • Molecular Weight: 1291.3

Experimental Properties

  • Density: 1.67±0.1 g/cm3 (20 oC 760 Torr),
  • Solubility: Almost insoluble (0.036 g/l) (25 o C),

Rebaudioside M Security Information

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Rebaudioside M Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
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(CAS:1220616-44-3)Rebaudioside M
Order Number:sfd9604
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
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(CAS:1220616-44-3)Rebaudioside M
Order Number:LE12542
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:07
Price ($):discuss personally

Additional information on Rebaudioside M

Rebaudioside M (CAS No. 1220616-44-3): A Comprehensive Overview

Rebaudioside M (CAS No. 1220616-44-3) is a high-potency sweetener derived from the leaves of the Stevia rebaudiana plant. This compound has gained significant attention in recent years due to its exceptional sweetness and low caloric content, making it an attractive alternative to traditional sugar and artificial sweeteners. This article provides a detailed overview of Rebaudioside M, including its chemical structure, biological properties, applications, and recent research developments.

Chemical Structure and Properties

Rebaudioside M is a glycoside composed of a steviol backbone and several glucose units. Its molecular formula is C36H60O18, and it has a molecular weight of 788.85 g/mol. The compound is highly soluble in water and exhibits excellent stability under various conditions, including heat, pH, and storage. These properties make it suitable for a wide range of food and beverage applications.

Biological Properties and Safety

Rebaudioside M is known for its intense sweetness, which is approximately 300-400 times that of sucrose. Unlike other steviol glycosides, Rebaudioside M has a more favorable taste profile with minimal bitterness or aftertaste. Extensive studies have demonstrated its safety for human consumption. The Joint FAO/WHO Expert Committee on Food Additives (JECFA) has established an Acceptable Daily Intake (ADI) of 4 mg/kg body weight for steviol glycosides, including Rebaudioside M.

Applications in Food and Beverage Industry

The unique properties of Rebaudioside M have led to its widespread use in the food and beverage industry. It is commonly used as a sugar substitute in products such as beverages, confectionery, baked goods, and dairy products. The compound's high sweetness and low caloric content make it an ideal choice for developing reduced-calorie and sugar-free products that meet consumer demands for healthier options.

Clinical Studies and Health Benefits

Recent clinical studies have explored the potential health benefits of Rebaudioside M. Research has shown that it may have beneficial effects on blood glucose levels, making it a suitable ingredient for individuals with diabetes or those at risk of developing the condition. Additionally, studies have indicated that steviol glycosides, including Rebaudioside M, may have anti-inflammatory and antioxidant properties, contributing to overall health and well-being.

Sustainability and Environmental Impact

The production of Rebaudioside M from the Stevia rebaudiana plant is considered more sustainable compared to traditional sugar production methods. The cultivation of stevia requires less land, water, and pesticides than sugar cane or beet crops. This makes it an environmentally friendly alternative that aligns with growing consumer preferences for sustainable products.

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Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:1220616-44-3)Rebaudioside M
sfd9604
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:1220616-44-3)Rebaudioside M
LE12542
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email