Cas no 122-59-8 (Phenoxyacetic acid)

Phenoxyacetic acid is a versatile chemical intermediate that offers several key advantages in various industrial applications. Its high reactivity and solubility make it an effective component in the production of pesticides, herbicides, and pharmaceuticals, allowing for efficient synthesis and reaction processes.
Phenoxyacetic acid structure
Phenoxyacetic acid structure
Product Name:Phenoxyacetic acid
CAS No:122-59-8
MF:C8H8O3
MW:152.147322654724
MDL:MFCD00004296
CID:36043
PubChem ID:19188
Update Time:2026-05-14

Phenoxyacetic acid Chemical and Physical Properties

Names and Identifiers

    • 2-Phenoxyacetic acid
    • FEMA 2872
    • Glycolic acid phenyl ether
    • O-PHENYLGLYCOLIC ACID
    • PHENOXYETHANOIC ACID
    • PHENYL ETHER GLYCOLIC ACID
    • PHENYLIUM(R)
    • PHENYLIUM(TM)
    • PHENYLOXYL ACETIC ACID
    • RARECHEM AL BO 0458
    • Acide phenoxyacetique
    • Glycollic acid phenyl ether
    • phenoxyacetic
    • PHENOXYACETIC ACID FREE ACID
    • Phenoxyacetic acid, purum
    • Phenoxyacetic acid
    • Phenoxyaceticacid Solution
    • 1-bromo-2-phenoxyethane
    • 1-bromo-2-phenyloxyethane
    • 1-phenoxy-2-bromoethane
    • 2-bromoethyl phenyl ether
    • 2-Phenoxy-acetic acid
    • 2-phenoxy-ethyl bromide
    • B-BROMOPHENETOLE
    • phenoxy-acetic acid
    • PHENOXYETHYLBROMIDE
    • PhO-CH2COOH
    • Phenylium
    • phenoxyacetc acid
    • Phenxoyacetic acid
    • AKOS BBS-00003724
    • Acetic acid, phenoxy-
    • Phenoxy acetic acid
    • Glycol acid phenyl ether
    • Phenoxyacetate
    • Acetic acid, 2-phenoxy-
    • Glycolic acid, phenyl ether
    • Phenoxyessigsaeure
    • Phenylglycolic acid, O-
    • Acide phenoxyacetique [French]
    • POA
    • phenoxacetic acid
    • FEMA No
    • Phenoxymethylpenicillin Potassium Imp. B: Phenoxyacetic Acid
    • MDL: MFCD00004296
    • Inchi: 1S/C8H8O3/c9-8(10)6-11-7-4-2-1-3-5-7/h1-5H,6H2,(H,9,10)
    • InChI Key: LCPDWSOZIOUXRV-UHFFFAOYSA-N
    • SMILES: O(C([H])([H])C(=O)O[H])C1C([H])=C([H])C([H])=C([H])C=1[H]
    • BRN: 907949

Computed Properties

  • Exact Mass: 152.04700
  • Monoisotopic Mass: 152.047344
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 3
  • Complexity: 127
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 1.3
  • Topological Polar Surface Area: 46.5

Experimental Properties

  • Color/Form: Not available
  • Density: 1.2143 (rough estimate)
  • Melting Point: 98-100?°C (lit.)
  • Boiling Point: 285°C(lit.)
  • Flash Point: 165 oC
  • Refractive Index: 1.4447 (estimate)
  • Solubility: ethanol: soluble10%, clear, colorless
  • Water Partition Coefficient: 0.1-0.5 g/100 mL at 17 oC
  • Stability/Shelf Life: Stable. Substances to be avoided include strong bases, strong oxidizing agents. Combustible.
  • PSA: 46.53000
  • LogP: 1.15000
  • Solubility: Not available
  • pka: 3.17(at 25℃)
  • FEMA: 2872
  • Merck: 7254

Phenoxyacetic acid Security Information

  • Symbol: GHS07
  • Prompt:warning
  • Signal Word:Warning
  • Hazard Statement: H302,H315,H319,H335
  • Warning Statement: P261,P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 22-36/37/38
  • Safety Instruction: S26-S36-S37/39
  • RTECS:AJ2230000
  • Hazardous Material Identification: Xn
  • TSCA:Yes
  • Storage Condition:Store at room temperature
  • Risk Phrases:R22; R36/37/38
  • Safety Term:S26;S37/39

Phenoxyacetic acid Customs Data

  • HS CODE:2942000000
  • Customs Data:

    China Customs Code:

    2918990090

    Overview:

    2918990090. Other additional oxy carboxylic acids(Including anhydrides\Acyl halide\Peroxides, peroxyacids and derivatives of this tax number). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Phenoxyacetic acid Pricemore >>

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Phenoxyacetic acid Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:122-59-8)2-cyclohexyloxyacetate
Order Number:LE6989;LE9310;LE2463864
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:50
Price ($):discuss personally
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:122-59-8)Phenoxyacetic acid
Order Number:sfd8168
Stock Status:in Stock
Quantity:200KG
Purity:99%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally

Phenoxyacetic acid Spectrogram

13C NMR
13C NMR
1H NMR 300 MHz DMSO
1H NMR

Phenoxyacetic acid Related Literature

Additional information on Phenoxyacetic acid

Phenoxyacetic acid (CAS No. 122-59-8): A Comprehensive Overview of Its Applications and Recent Research Developments

Phenoxyacetic acid, with the chemical formula C7H6O3, is a versatile organic compound widely recognized for its significant role in various chemical and pharmaceutical applications. Its molecular structure, featuring a phenyl group and an acetic acid moiety, endows it with unique reactivity and functional properties that make it invaluable in synthetic chemistry, agrochemicals, and medicinal research.

The compound is formally known by the CAS number 122-59-8, which distinguishes it from other isomers and derivatives. This numbering system ensures precise identification and classification within the scientific community, facilitating accurate documentation and communication in research papers, patents, and industrial applications.

Phenoxyacetic acid is primarily utilized as an intermediate in the synthesis of various agrochemicals, including herbicides and plant growth regulators. Its phenolic group allows for easy modification, enabling the development of compounds with tailored biological activities. For instance, derivatives of phenoxyacetic acid have been extensively studied for their efficacy in controlling unwanted vegetation without harming crops.

In the realm of pharmaceutical research, phenoxyacetic acid has garnered attention due to its potential as a precursor for bioactive molecules. Recent studies have explored its role in developing novel therapeutic agents targeting metabolic disorders and inflammatory conditions. The compound's ability to interact with biological targets at the molecular level has opened new avenues for drug discovery.

A notable derivative of phenoxyacetic acid, often referred to as its long-tail keyword p-hydroxyphenoxyacetic acid, has been investigated for its anti-inflammatory properties. Research published in recent years indicates that this derivative can modulate key signaling pathways involved in inflammation, suggesting its potential as a lead compound for developing anti-inflammatory drugs.

The synthesis of phenoxyacetic acid typically involves the reaction of phenol with chloroacetic acid under controlled conditions. This process highlights its importance as a building block in organic synthesis. Advances in synthetic methodologies have improved the efficiency and scalability of its production, making it more accessible for industrial applications.

In addition to its agrochemical and pharmaceutical uses, phenoxyacetic acid finds applications in material science and chemical research. Its reactivity with other compounds allows for the creation of polymers and specialty chemicals with specific properties. For example, it has been used to develop corrosion inhibitors and surface-active agents.

Recent research has also delved into the environmental impact of phenoxyacetic acid and its derivatives. Studies have examined their persistence in aquatic ecosystems and their potential effects on non-target organisms. These investigations are crucial for developing sustainable practices in agriculture and pharmaceutical manufacturing, ensuring minimal environmental footprint.

The development of new analytical techniques has enhanced our ability to study phenoxyacetic acid at the molecular level. Techniques such as nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry provide detailed insights into its structure and interactions with other molecules. This information is vital for optimizing its use in various applications.

P-hydroxyphenoxyacetic acid, a key derivative of phenoxyacetic acid, has been the focus of several innovative studies aimed at understanding its pharmacological properties. Research suggests that it may have neuroprotective effects, making it a candidate for treating neurodegenerative diseases. These findings underscore the importance of continued research into this compound class.

The industrial production of phenoxyacetic acid has seen significant advancements in recent years, driven by demand from multiple sectors. Manufacturers have adopted greener synthetic routes, reducing waste and energy consumption while maintaining high yields. Such innovations align with global efforts to promote sustainable chemistry practices.

The role of phenoxyacetic acid in drug development continues to expand as researchers uncover new therapeutic potentials. Its ability to modulate biological pathways makes it a valuable scaffold for designing drugs targeting a wide range of diseases. Collaborative efforts between academia and industry are essential to translate these findings into clinical applications.

In conclusion, phenoxyacetic acid (CAS No. 122-59-8) is a multifunctional compound with broad applications across multiple industries. Its unique chemical properties make it indispensable in synthetic chemistry, agrochemicals, pharmaceuticals, and material science. Ongoing research continues to uncover new uses and derivatives, reinforcing its significance in modern science and industry.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
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Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:122-59-8)Phenoxyacetic acid
sfd8168
Purity:99%
Quantity:200KG
Price ($):Inquiry
Email